Výsledky vyhledávání - "MESH : Pluripotent Stem Cells"

Induction of Human Naïve Pluripotent Stem Cells from Somatic Cells

Autor: Constance Onfray, Jia Ping Tan, Stéphanie Kilens, Xiaodong Liu, Jose Polo, Laurent David

Publikováno v: Human Naïve Pluripotent Stem Cells
Human Naïve Pluripotent Stem Cells, 2416, Springer US, pp.39-51, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-1908-7_4⟩
Methods in Molecular Biology ISBN: 9781071619070

International audience; Generating patient-specific stem cells representing the onset of development has become possible since the discovery of somatic cell reprogramming into induced pluripotent stem cells. However, human pluripotent stem cells are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b786384ba408f82a9fe3fe75fa6250b
https://pubmed.ncbi.nlm.nih.gov/34870829

Zobrazit plný text záznamu

Dynamic extrinsic pacing of the HOX clock in human axial progenitors controls motor neuron subtype specification

Autor: Hynek Wichterle, Virginie Rouiller-Fabre, Nour Nicolas, Gist F. Croft, Vincent Mouilleau, Vanessa Ribes, Léa Lesueur, Célia Vaslin, Mathieu Daynac, Stéphane Nedelec, Angélique Terray, Margot Jarrige, Simona Gribaudo, Mackenzie W. Mathis, Cécile Martinat, Rémi Robert

Publikováno v: Development (Cambridge, England)
Development (Cambridge, England), 2021, 148 (6), ⟨10.1242/dev.194514⟩
Development

Rostro-caudal patterning of vertebrates depends on the temporally progressive activation of HOX genes within axial stem cells that fuel axial embryo elongation. Whether the pace of sequential activation of HOX genes, the 'HOX clock', is controlled by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e0481a9887cbd9be52c24e87935e7c
https://hal.science/hal-03550019

Zobrazit plný text záznamu

Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases

Publikováno v: Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2020, 22 (10), pp.1223-1238. ⟨10.1038/s41556-020-0573-1⟩
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Cell Biology, 2020, 22 (10), pp.1223-1238. ⟨10.1038/s41556-020-0573-1⟩
research@ua; Vol 11 (2020); 49
research@ua; vol. 11 (2020); 49
Digital.CSIC. Repositorio Institucional del CSIC
instname

Pluripotent stem cells (PSCs) transition between cell states in vitro, reflecting developmental changes in the early embryo. PSCs can be stabilized in the naive state by blocking extracellular differentiation stimuli, particularly FGF–MEK signallin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e6662dbd5d60ba17897bdaeae5b24d
https://hal.archives-ouvertes.fr/hal-03234133

Zobrazit plný text záznamu

Pipeline for the Generation and Characterization of Transgenic Human Pluripotent Stem Cells Using the CRISPR/Cas9 Technology

Autor: Chloé Bourguignon, John De Vos, Amel Nasri, Chloé Nguyen Van, Mathieu Fieldes, Joffrey Mianné, Said Assou

Publikováno v: Cells
Cells, MDPI, 2020, 9 (5), pp.1312. ⟨10.3390/cells9051312⟩
Cells, Vol 9, Iss 1312, p 1312 (2020)

International audience; Recent advances in genome engineering based on the CRISPR/Cas9 technology have revolutionized our ability to manipulate genomic DNA. Its use in human pluripotent stem cells (hPSCs) has allowed a wide range of mutant cell lines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e916c248fc17e1679cefe37516369cb
https://hal.umontpellier.fr/hal-03594394

Zobrazit plný text záznamu

GP130 signaling and the control of naïve pluripotency in humans, monkeys, and pigs

Autor: Laurent David, Claire Santamaria, Pierre-Yves Bourillot, Pierre Savatier

Publikováno v: Experimental Cell Research
Experimental Cell Research, 2020, 386 (1), pp.111712. ⟨10.1016/j.yexcr.2019.111712⟩
Experimental Cell Research, Elsevier, 2020, 386 (1), pp.111712. ⟨10.1016/j.yexcr.2019.111712⟩

International audience; The leukemia inhibitory factor (LIF)/glycoprotein (GP) 130/Janus kinase (JAK)/signal transducer and activator of transcription (STAT) 3 signaling pathway is a hallmark of naïve pluripotency in mice. In this review, we discuss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fcc86bed2c31a31a4900b49cd552fa0
https://hal.archives-ouvertes.fr/hal-02424459/file/S0014482719305919.pdf

Zobrazit plný text záznamu

Recurrent genetic abnormalities in human pluripotent stem cells: definition and routine detection in culture supernatant by targeted droplet digital PCR

Autor: Mathieu Fieldes, Thérèse Commes, Anthony Boureux, Julien Bouckenheimer, Chloé Bourguignon, Caroline Sansac, Joffrey Mianné, Said Assou, Engi Ahmed, Mathilde Plinet, Marion Combe, Nicolas Girault, Jean-Marc Lemaitre, John De Vos

Publikováno v: Stem Cell Reports
Stem Cell Reports, Elsevier, 2020, 14 (1), pp.1-8. ⟨10.1016/j.stemcr.2019.12.004⟩
Stem Cell Reports, Vol 14, Iss 1, Pp 1-8 (2020)

Summary Genomic integrity of human pluripotent stem cells (hPSCs) is essential for research and clinical applications. However, genetic abnormalities can accumulate during hPSC generation and routine culture and following gene editing. Their occurren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848c78fc7ab8ab04b613b8a4569e41ea

Zobrazit plný text záznamu

Establishment of a collection of human pluripotent stem cell lines (iPSC) from mesenchymal stem cells (MSC) from three healthy elderly donors

Autor: Fabienne Becker, P. Pastoureau, Christian Jorgensen, Danièle Noël, Lydiane Pichard, Frédéric De Ceuninck, Jean-Marc Lemaitre, Romain Desprat, Jean-Marc Brondello

Publikováno v: Stem Cell Research
Stem Cell Research, Elsevier, 2021, 53, pp.102297. ⟨10.1016/j.scr.2021.102297⟩
Stem Cell Research, Vol 53, Iss, Pp 102297-(2021)

International audience; The study of molecular mechanism driving osteoarticular diseases like osteoarthritis or osteoporosis is impaired by the low accessibility to mesenchymal stem cells (MSC) from healthy donors (HD) for differential multi-omics an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae20aa2f1ddfc08003a49a99ce34ca5d
https://doi.org/10.1016/j.scr.2021.102297

Zobrazit plný text záznamu

Human Pluripotent Stem-Cell-Derived Cortical Neurons Integrate Functionally into the Lesioned Adult Murine Visual Cortex in an Area-Specific Way

Autor: Pierre Vanderhaeghen, Adèle Herpoel, Sandra Acosta-Verdugo, Daniele Linaro, Afsaneh Gaillard, Angéline Bilheu, Ira Espuny-Camacho, Michele Giugliano, Kimmo A. Michelsen

Publikováno v: Cell reports
Cell Reports, Vol 23, Iss 9, Pp 2732-2743 (2018)
Cell Reports
Cell Reports, Elsevier Inc, 2018, 23 (9), pp.2732-2743. ⟨10.1016/j.celrep.2018.04.094⟩
Cell reports, 23 (9

Summary The transplantation of pluripotent stem-cell-derived neurons constitutes a promising avenue for the treatment of several brain diseases. However, their potential for the repair of the cerebral cortex remains unclear, given its complexity and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3634cc91c8b3f7edbdb3ed8ec7f4f30
https://lirias.kuleuven.be/handle/123456789/647822

Zobrazit plný text záznamu

Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro

Autor: Ziad Al Tanoury, Shahragim Tajbakhsh, Barbara Gayraud-Morel, Philippe Moncuquet, Jérome Chal, Jean-Marie Garnier, Olivier Pourquié, Olivier Tassy, Agata Bera, Olga Sumara, Masayuki Oginuma, Alexis Hubaud, Getzabel Guevara, Leif Kennedy, Marie Knockaert, Ayako Miyanari, Bénédicte Gobert

Publikováno v: Development (Cambridge, England)
Development (Cambridge, England), 2018, 145 (6), pp.dev157339. ⟨10.1242/dev.157339⟩
Development (Cambridge, England), Company of Biologists, 2018, 145 (6), pp.dev157339. ⟨10.1242/dev.157339⟩

The work described in this article is partially covered by patent application PCT/EP2012/066793 (publication number WO2013030243 A1). O.P., J.C. and M.K. are co-founders and shareholders of Anagenesis Biotechnologies, a start-up company specializing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c879a49492fae97230915caf68540b0
https://hal-pasteur.archives-ouvertes.fr/pasteur-03217358

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání