MAX Mutations Cause Hereditary and Sporadic Pheochromocytoma and Paraganglioma

Autor: Patricia L. M. Dahia, Maurizio Castellano, Nicole Reisch, Carli M. J. Tops, N. Abermil, Marta Barontini, Graeme Eisenhofer, Sandra Bernaldo de Quirós, Salud Borrego, Álvaro Gómez-Graña, Nelly Burnichon, M. Giacchè, Mercedes Robledo, Emiliano Honrado, Giuseppe Opocher, Francesca Schiavi, Xavier Girerd, Elena Rapizzi, Lucía Inglada-Pérez, Esther Korpershoek, Henri J L M Timmers, Massimo Mannelli, Encarna B. Gomez-Garcia, Elisa Taschin, María-Dolores Chiara, Sara Bobisse, Alberto Cascón, Peggy Pierre, Carlos Suárez, Alexander P.A. Stegmann, Arjen R. Mensenkamp, Felix Beuschlein, Luigi Mori, Iñaki Comino-Méndez, Marinus J. Blok, Laurence Amar, Arnaud Murat, Macarena Ruiz-Ferrer, Ronald R. de Krijger, F Schillo, Frederik J. Hes, Karel Pacak, Nicole Paes Morales, Tonino Ercolino, Jacques W.M. Lenders, Rocío Letón, Miguel Urioste, Eleonora P M Corssmit, Isabelle Guilhem, Nan Qin, Anne-Paule Gimenez-Roqueplo, Giovanna Roncador, Pierre-François Plouin, Tamara Prodanov, Yves-Jean Bignon, Victoria M. Raymond, Jérôme Bertherat, Miguel Quesada-Charneco, Anna Merlo, Aguirre A. de Cubas, Philippe Chanson

Publikováno v: Clinical Cancer Research
Clinical Cancer Research, 2012, 18 (10), pp.2828-37. ⟨10.1158/1078-0432.CCR-12-0160⟩
Clinical Cancer Research, 18(10), 2828-2837. American Association for Cancer Research Inc.
Clinical Cancer Research, American Association for Cancer Research, 2012, 18 (10), pp.2828-37. ⟨10.1158/1078-0432.CCR-12-0160⟩
Clinical Cancer Research, 18, 10, pp. 2828-37
Digital.CSIC. Repositorio Institucional del CSIC
instname
Clinical Cancer Research, 18(10), 2828-2837
Clinical Cancer Research, American Association for Cancer Research, 2012, 18 (10), pp.2828-37. 〈10.1158/1078-0432.CCR-12-0160〉
Clinical Cancer Research; Vol 18
Clinical Cancer Research, 18, 2828-37

11 pages, 2 figures, 2 tables.-- Burnichón, Nelly et al.
Purpose: Pheochromocytomas (PCC) and paragangliomas (PGL) are genetically heterogeneous neural crest-derived neoplasms. Recently we identified germline mutations in a new tumor suppressor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741d2c9a7a3e90b407fce3123fe7e415
http://hdl.handle.net/11379/148720

First report of bilateral pheochromocytoma in the clinical spectrum of HIF2A-related polycythemia-paraganglioma syndrome

Autor: Blandine Delenne, Anne Barlier, Frederic Sebag, Zhengping Zhuang, Chunzhang Yang, Karel Pacak, David Taïeb

Publikováno v: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, 2013, 98 (5), pp.E908-13. ⟨10.1210/jc.2013-1217⟩
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2013, 98 (5), pp.E908-13. ⟨10.1210/jc.2013-1217⟩

International audience; CONTEXT: Molecular genetic research has so far resulted in the identification of 10 well-characterized susceptibility genes for hereditary pheochromocytoma (PHEO) or paraganglioma (PGL). Recently, a new syndrome characterized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155cef502f9d246581fd8bdc59491bfa
https://hal.science/hal-00966232

Prognostic value of Pheochromocytoma of the Adrenal Gland Scaled Score (Pass score) tests to separate benign from malignant neoplasms

Autor: Mlika, Mona, Kourda, Nadia, Zorgati, Mohamed Majdi, Bahri, Sonia, Ben Ammar, Slim, Zermani, Rachida

Publikováno v: Tunisie Medicale
Tunisie Medicale, Maghreb-Editions; 1999, 2013, 91 (3), pp.209-215

BACKGROUND: Differentiating malignant from benign pheochromocytoma has been challenging when based on histologic features. This is due to the definition of malignant pheochromocytoma which are defined by the presence of metastases. A PASS score was d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c456f1cd1a5cbcb276d2f6b21e4593bb
https://hal-riip.archives-ouvertes.fr/pasteur-02052091

Expression and processing of the neuroendocrine protein secretogranin II in benign and malignant pheochromocytomas

Autor: Marc Klein, Maité Montero-Hadjadje, Virginie Vallet-Erdtmann, Laure Barbier, Laurent Yon, Nabil G. Seidah, Hervé Lefebvre, Pierre-François Plouin, Erwan Thouënnon, Johann Guillemot, Hubert Vaudry, Mihaela Muresan, Youssef Anouar

Publikováno v: Annals of the New York Academy of Sciences
Annals of the New York Academy of Sciences, Wiley, 2006, 1073, pp.527-32. ⟨10.1196/annals.1353.056⟩
Annals of the New York Academy of Sciences, 2006, 1073, pp.527-32. ⟨10.1196/annals.1353.056⟩

International audience; The aim of the present study was to compare the expression levels of secretogranin II (SgII), prohormone convertases (PC)1 and PC2, and the proteolytic processing of SgII in benign versus malignant pheochromocytomas. Quantitat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad3f3f5c57a867b29cd82e221c0c9bf
https://pubmed.ncbi.nlm.nih.gov/17102121

Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase

Autor: Youssef Aissouni, Bertrand Tavitian, Domenico Libri, Carine Pestourie, Frédéric Ducongé, Laura Cerchia, Jocelyne Boulay, Karine Gombert, Vittorio de Franciscis

Publikováno v: PLoS Biology
PLoS Biology, 2005, 3 (4), pp.e123. ⟨10.1371/journal.pbio.0030123⟩
PLoS biology 3 (2005): 697–704. doi:10.1371/journal.pbio.0030123.g003
info:cnr-pdr/source/autori:Laura Cerchia 1; Frederic Duconge 2; Carine Pestourie 2; Jocelyne Boulay 3; Youssef Aissouni 3; Karine Gombert 2; Bertrand Tavitian 2; Vittorio de Franciscis 1; Domenico Libri 3/titolo:Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase/doi:10.1371%2Fjournal.pbio.0030123.g003/rivista:PLoS biology/anno:2005/pagina_da:697/pagina_a:704/intervallo_pagine:697–704/volume:3
PLoS Biology, Public Library of Science, 2005, 3 (4), pp.e123. ⟨10.1371/journal.pbio.0030123⟩
PLoS Biology, Vol 3, Iss 4, p e123 (2005)
Scopus-Elsevier

Targeting large transmembrane molecules, including receptor tyrosine kinases, is a major pharmacological challenge. Specific oligonucleotide ligands (aptamers) can be generated for a variety of targets through the iterative evolution of a random pool

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9603f14bcfb8b45f427f82d0c6a22966
https://hal-cea.archives-ouvertes.fr/cea-00161297/document