Zobrazeno 1 - 10
of 26
pro vyhledávání: '"MESH : Peptide Hormones"'
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (23), pp.9838-9859. ⟨10.1021/acs.jmedchem.7b01525⟩
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (23), pp.9838-9859. ⟨10.1021/acs.jmedchem.7b01525⟩
International audience; Benzotriazepin-2-ones were designed to mimic the suggested bioactive γ-turn conformation of the Bip-Lys-Tyr tripeptide in Urocontrin ([Bip4]URP), which modulates the urotensin II receptor (UT) and differentiates the effects o
Publikováno v:
Advances in Experimental Medicine and Biology
Advances in Experimental Medicine and Biology, Kluwer, 2012, 83 (5), pp.608-15. ⟨10.1016/j.bcp.2011.12.009⟩
Advances in Experimental Medicine and Biology, Kluwer, 2012, 83 (5), pp.608-15. ⟨10.1016/j.bcp.2011.12.009⟩
International audience; In recent years, several studies have demonstrated that urotensin II (UII) and urotensin II-related peptide (URP) can exhibit differential biological activity. So far, known antagonists of the urotensin II receptor (UT) are of
Autor:
Hubert Vaudry, David Chatenet, Daniel Davoust, Pierre Pacaud, Christophe Dubessy, Laure Guilhaudis, Alain Fournier, Bruno Pfeiffer, Hassan Oulyadi, Marie-Christine Tonon, Jérôme Leprince, Pierre Renard, Elizabeth Scalbert, Isabelle Ségalas-Milazzo
Publikováno v:
Peptides
Peptides, Elsevier, 2008, 29 (5), pp.658-673. ⟨10.1016/j.peptides.2007.08.014⟩
Peptides, Elsevier, 2008, 29 (5), pp.658-673. ⟨10.1016/j.peptides.2007.08.014⟩
International audience; Urotensin II (U-II) and urotensin II-related peptide (URP) are the endogenous ligands for the orphan G-protein-coupled receptor GPR14 now renamed UT. At the periphery, U-II and/or URP exert a wide range of biological effects o
Autor:
Eithne O’Grady, Maria Gueorguiev, Cécile Lecoeur, Charles A. Mein, Ashley B. Grossman, Philippe Froguel, Daniel Swan, Márta Korbonits, Jacques Weill
Publikováno v:
Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2002, 87 (8), pp.4005-8
Journal of Clinical Endocrinology and Metabolism, 2002, 87 (8), pp.4005-8
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2002, 87 (8), pp.4005-8
Journal of Clinical Endocrinology and Metabolism, 2002, 87 (8), pp.4005-8
Ghrelin is a recently recognized gut-brain peptide originally derived from the gastric mucosa. It stimulates growth hormone release, increases appetite and facilitates fat storage, and may interact with glucose metabolism. We studied the ghrelin gene
Autor:
Bucharles, Christine, Bizet, Patrice, Arthaud, Sébastien, Arabo, Arnaud, Leprince, Jérôme, Lefranc, Benjamin, Cartier, Dorthe, Anouar, Youssef, Lihrmann, Isabelle
Publikováno v:
Journal of Comparative Neurology
Journal of Comparative Neurology, John Wiley & Sons, 2014, 522 (11), pp.2634-2649. ⟨10.1002/cne.23553⟩
Journal of Comparative Neurology, John Wiley & Sons, 2014, 522 (11), pp.2634-2649. ⟨10.1002/cne.23553⟩
International audience; Urotensin II (UII) and Urotensin II-related peptide (URP) are structurally related paralog peptides that exert peripheral and central effects. UII binding sites have been partly described in brain, and those of URP have never
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::954f91a98057360078ae5c6f9306e4ad
https://hal.archives-ouvertes.fr/hal-01939220
https://hal.archives-ouvertes.fr/hal-01939220
Autor:
Philippe Saas, Daniel Wendling, Nhu Uyen Nguyen, Gilles Dumoulin, Eric Toussirot, Gérald Streit, Gaëlle Le Huédé
Publikováno v:
Metabolism
Metabolism, WB Saunders, 2007, 56 (10), pp.1383-9. 〈10.1016/j.metabol.2007.05.009〉
Metabolism, Elsevier, 2007, 56 (10), pp.1383-9. ⟨10.1016/j.metabol.2007.05.009⟩
Metabolism, WB Saunders, 2007, 56 (10), pp.1383-9. 〈10.1016/j.metabol.2007.05.009〉
Metabolism, Elsevier, 2007, 56 (10), pp.1383-9. ⟨10.1016/j.metabol.2007.05.009⟩
International audience; Adipokines such as leptin and adiponectin are involved in the regulation of inflammation. Ghrelin, a gastric peptide playing a role in the appetite regulation, possesses anti-inflammatory properties. In this study, we evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b985a5a2ac40761cc0e790c3995cfe
https://hal.archives-ouvertes.fr/hal-00465201
https://hal.archives-ouvertes.fr/hal-00465201
Autor:
Marie-Thérèse Bluet-Pajot, Rodrigo Alvear-Perez, Philippe Zizzari, Catherine Llorens-Cortes, Annabelle Réaux-Le Goazigo, Jacques Epelbaum
Publikováno v:
AJP-Endocrinology and Metabolism
AJP-Endocrinology and Metabolism, 2007, 292 (1), pp.E7-15. ⟨10.1152/ajpendo.00521.2005⟩
AJP-Endocrinology and Metabolism, American Physiological Society, 2007, 292 (1), pp.E7-15. ⟨10.1152/ajpendo.00521.2005⟩
AJP-Endocrinology and Metabolism, American Physiological Society, 2007, 292 (1), pp.E7-15. 〈10.1152/ajpendo.00521.2005〉
AJP-Endocrinology and Metabolism, 2007, 292 (1), pp.E7-15. ⟨10.1152/ajpendo.00521.2005⟩
AJP-Endocrinology and Metabolism, American Physiological Society, 2007, 292 (1), pp.E7-15. ⟨10.1152/ajpendo.00521.2005⟩
AJP-Endocrinology and Metabolism, American Physiological Society, 2007, 292 (1), pp.E7-15. 〈10.1152/ajpendo.00521.2005〉
Apelin is a bioactive peptide recently identified as the endogenous ligand of the human orphan G protein-coupled receptor APJ. The presence of apelin-immunoreactive nerve fibers, together with the detection of apelin receptor mRNA in the parvocellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b2e5f2363812a8fd750c2ac1c444af
https://www.hal.inserm.fr/inserm-00422910
https://www.hal.inserm.fr/inserm-00422910
Autor:
Jacques Epelbaum, Philippe Zizzari, Marie-Thérèse Bluet-Pajot, Laurent Kappeler, Josette Alliot
Publikováno v:
Neuroendocrinology
Neuroendocrinology, Karger, 2004, 80 (5), pp.273-83. 〈10.1159/000083610〉
Neuroendocrinology, 2004, 80 (5), pp.273-83. ⟨10.1159/000083610⟩
Neuroendocrinology, Karger, 2004, 80 (5), pp.273-83. ⟨10.1159/000083610⟩
Neuroendocrinology, Karger, 2004, 80 (5), pp.273-83. 〈10.1159/000083610〉
Neuroendocrinology, 2004, 80 (5), pp.273-83. ⟨10.1159/000083610⟩
Neuroendocrinology, Karger, 2004, 80 (5), pp.273-83. ⟨10.1159/000083610⟩
International audience; Since modifications in the growth hormone/insulin-like growth factor 1 (GH/IGF-1) axis and/or caloric restriction are involved in the ageing process, GH secretory profiles, total IGF-1, ghrelin, and leptin plasma levels and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56c897f08484f7de64818e165ec14ff
http://www.hal.inserm.fr/inserm-00117247/file/Kappeler2004.pdf
http://www.hal.inserm.fr/inserm-00117247/file/Kappeler2004.pdf
Publikováno v:
British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2012, 166 (1), pp.243-57. ⟨10.1111/j.1476-5381.2011.01710.x⟩
British Journal of Pharmacology, Wiley, 2012, 166 (1), pp.243-57. ⟨10.1111/j.1476-5381.2011.01710.x⟩
International audience; BACKGROUND AND PURPOSE During the past decade, a few GPCRs have been characterized at the nuclear membrane where they exert complementary physiological functions. In this study, we investigated (1) the presence of a functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e46490afcda66c16b7a632803773b9b7
https://europepmc.org/articles/PMC3415652/
https://europepmc.org/articles/PMC3415652/
Autor:
Chartrel, C, Alvear-Perez, P, Iturrioz, X., Reaux-Le Goazigo, A., Audinot, V., Chomarat, C, Coge, C, Nosjean, O., Rodriguez, M., Galizzi, J., Goazigo, R., Chomarat, P., Coge, F., Chartrel, Nicolas, Alonzeau, Jessy, Alexandre, David, Jeandel, Jean, Alvear-Perez, Rodrigo, Leprince, Jérôme, Boutin, Jean, Vaudry, Hubert, Anouar, Youssef, Llorens-Cortes, Catherine, Jeandel, Lydie
Publikováno v:
Frontiers in Neuroendocrinology
Frontiers in Neuroendocrinology, Elsevier, 2011, 32 (4), pp.387-397. ⟨10.1016/j.yfrne.2011.04.001⟩
Frontiers in Neuroendocrinology, 2011, 32 (4), pp.387-397. ⟨10.1016/j.yfrne.2011.04.001⟩
Frontiers in Neuroendocrinology, Elsevier, 2011, 32 (4), pp.387-397. ⟨10.1016/j.yfrne.2011.04.001⟩
Frontiers in Neuroendocrinology, 2011, 32 (4), pp.387-397. ⟨10.1016/j.yfrne.2011.04.001⟩
International audience; Identification of novel neuropeptides and their cognate G protein-coupled receptors is essential for a better understanding of neuroendocrine regulations. The RFamide peptides represent a family of regulatory peptides that all