Zobrazeno 1 - 10
of 16
pro vyhledávání: '"MESH : P-Glycoprotein"'
Publikováno v:
Brain Research
Brain Research, Elsevier, 2007, 1134 (1), pp.1-11. ⟨10.1016/j.brainres.2006.11.089⟩
Brain Research, 2007, 1134 (1), pp.1-11. ⟨10.1016/j.brainres.2006.11.089⟩
Brain Research, Elsevier, 2007, 1134 (1), pp.1-11. 〈10.1016/j.brainres.2006.11.089〉
Brain Research, Elsevier, 2007, 1134 (1), pp.1-11. ⟨10.1016/j.brainres.2006.11.089⟩
Brain Research, 2007, 1134 (1), pp.1-11. ⟨10.1016/j.brainres.2006.11.089⟩
Brain Research, Elsevier, 2007, 1134 (1), pp.1-11. 〈10.1016/j.brainres.2006.11.089〉
International audience; Quantitative RT-PCR (qRT-PCR) and Western blotting studies on transporters at the blood-brain barrier (BBB) of isolated brain microvessels have produced conflicting data on their cellular distribution. A major problem is ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eaace5284001a83b084f17b47d20cf3
https://doi.org/10.1016/j.brainres.2006.11.089
https://doi.org/10.1016/j.brainres.2006.11.089
Autor:
Marie-Françoise Belin, Ian D. Clarke, Nicole Assard, Jacques Baudier, Laurent Balenci, François Ducray, Peter B. Dirks, Anne Jouvet, Jérôme Honnorat
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2006, 66 (18), pp.9074-82. ⟨10.1158/0008-5472.CAN-06-0761⟩
Cancer Research, 2006, 66 (18), pp.9074-82. ⟨10.1158/0008-5472.CAN-06-0761⟩
Cancer Research, American Association for Cancer Research, 2006, 66 (18), pp.9074-82. ⟨10.1158/0008-5472.CAN-06-0761⟩
Cancer Research, 2006, 66 (18), pp.9074-82. ⟨10.1158/0008-5472.CAN-06-0761⟩
The accurate identification and thorough characterization of tumorigenic cells in glioblastomas are essential to enhance our understanding of their malignant behavior and for the design of strategies that target this important cell population. We rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ac70e10d4f8400ad09804de0e04d42
https://doi.org/10.1158/0008-5472.can-06-0761
https://doi.org/10.1158/0008-5472.can-06-0761
Autor:
Désiré Challuau, Benoît Hosten, Michel Perricaudet, Céline Bouquet, Sylvie Marion, Sophie Gil, Robert Farinotti, Mario Di Palma, Laurence Bonhomme-Faivre
Publikováno v:
Anti-Cancer Drugs
Anti-Cancer Drugs, Lippincott, Williams & Wilkins, 2006, 17 (2), pp.195-9
Anti-Cancer Drugs, Lippincott, Williams & Wilkins, 2006, 17 (2), pp.195-9
International audience; The aim of the present study was to examine modifications of anti-tumor activity and toxicity of paclitaxel (PLX) when given p.o. after recombinant interleukin-2 (rIL-2) to Lewis lung carcinoma-bearing mice. PLX was given oral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce51685c97b1105e926891843995a73
https://doi.org/10.1097/00001813-200602000-00011
https://doi.org/10.1097/00001813-200602000-00011
Autor:
Yves Artur, Christine Belloir, Nicolas Thiebaud, Anne-Marie Le Bon, Jean-Marie Heydel, Franck Ménétrier, Anne-Laure Minn, Fabrice Neiers
Publikováno v:
Neuroscience Letters
Neuroscience Letters, Elsevier, 2011, 505 (2), pp.180-5. ⟨10.1016/j.neulet.2011.10.018⟩
Neuroscience Letters, Elsevier, 2011, 505 (2), pp.180-5. 〈10.1016/j.neulet.2011.10.018〉
Neuroscience Letters, Elsevier, 2011, 505 (2), pp.180-5. ⟨10.1016/j.neulet.2011.10.018⟩
Neuroscience Letters, Elsevier, 2011, 505 (2), pp.180-5. 〈10.1016/j.neulet.2011.10.018〉
International audience; Transporters, such as multidrug resistance P-glycoproteins (MDR), multidrug resistance-related proteins (MRP) and organic anion transporters (OATs), are involved in xenobiotic metabolism, particularly the cellular uptake or ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd293f26b76aae1bb02835f3e6270bb5
https://hal.archives-ouvertes.fr/hal-00755577
https://hal.archives-ouvertes.fr/hal-00755577
Autor:
Nassera Aouali, Lahcen Eddabra, Hassan El Btaouri, Claudie Madoulet, Hamid Morjani, Charles Dumontet, Sophie Malagarie-Cazenave
Publikováno v:
Oncology Reports
Oncology Reports, Spandidos Publications, 2011, 25 (4), pp.1161-7. 〈10.3892/or.2011.1180〉
Oncology Reports, Spandidos Publications, 2011, 25 (4), pp.1161-7. ⟨10.3892/or.2011.1180⟩
Oncology Reports, Spandidos Publications, 2011, 25 (4), pp.1161-7. 〈10.3892/or.2011.1180〉
Oncology Reports, Spandidos Publications, 2011, 25 (4), pp.1161-7. ⟨10.3892/or.2011.1180⟩
International audience; The selection pressure for resistance to chemotherapy is accompanied by the enhanced expression of ABC proteins and increased cellular glycosphingolipid content. Thus, a possible connection between glycosphingolipid metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3533101879df2b23e9d6bdd90421dc
https://hal.archives-ouvertes.fr/hal-00771766
https://hal.archives-ouvertes.fr/hal-00771766
Autor:
Lamoureux, Fabien, Picard, Nicolas, Boussera, Belkacem, Sauvage, François-Ludovic, Marquet, Pierre
Publikováno v:
Fundamental and Clinical Pharmacology
Fundamental and Clinical Pharmacology, Wiley, 2012, 26 (4), pp.463-72. ⟨10.1111/j.1472-8206.2011.00957.x⟩
Fundamental & Clinical Pharmacology
Fundamental & Clinical Pharmacology, Wiley, 2012, 26 (4), pp.463-72. ⟨10.1111/j.1472-8206.2011.00957.x⟩
Fundamental and Clinical Pharmacology, Wiley, 2012, 26 (4), pp.463-72. ⟨10.1111/j.1472-8206.2011.00957.x⟩
Fundamental & Clinical Pharmacology
Fundamental & Clinical Pharmacology, Wiley, 2012, 26 (4), pp.463-72. ⟨10.1111/j.1472-8206.2011.00957.x⟩
International audience; The mTOR inhibitors (ImTORs) sirolimus (SRL) and everolimus (EVR) have been increasingly used in renal transplantation as part of calcineurin inhibitor (CNI) sparing or avoidance regimens. Those drugs have low and variable ora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::014ce8f922462bf9e2c82a06f2e9d3ee
https://pubmed.ncbi.nlm.nih.gov/21631587
https://pubmed.ncbi.nlm.nih.gov/21631587
Autor:
Nicolas Picard, Pierre Marquet
Publikováno v:
Expert Opinion on Drug Metabolism and Toxicology
Expert Opinion on Drug Metabolism and Toxicology, Taylor & Francis, 2011, 7 (6), pp.731-43. ⟨10.1517/17425255.2011.570260⟩
Expert Opinion on Drug Metabolism and Toxicology, Taylor & Francis, 2011, 7 (6), pp.731-43. ⟨10.1517/17425255.2011.570260⟩
International audience; INTRODUCTION: Immunosuppressive drugs have a narrow therapeutic range and large inter-individual response variability. This has prompted pharmacogenetic studies, mostly with regard to their dose-concentration relationships, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff6bdbec013c84be1c6ebf26af4f4cc
https://www.hal.inserm.fr/inserm-00577136
https://www.hal.inserm.fr/inserm-00577136
Autor:
Monidarin Chou, Julie Bertrand, Olivier Segeral, Céline Verstuyft, Laurence Borand, Emmanuelle Comets, Clotilde Le Tiec, Laurent Becquemont, Vara Ouk, France Mentre, Anne-Marie Taburet
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2010, 54 (10), pp.4432-9. ⟨10.1128/AAC.00512-10⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2010, 54 (10), pp.4432-9. ⟨10.1128/AAC.00512-10⟩
The aims of this ANRS12154 open-label, single-center, multiple-dose pharmacokinetic study were to characterize nevirapine pharmacokinetics in a Cambodian population of HIV-infected patients and to identify environmental and genetic factors of variabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146c7e5b8fffdeedc5e0d1f61d364fe8
https://pubmed.ncbi.nlm.nih.gov/20696882
https://pubmed.ncbi.nlm.nih.gov/20696882
Autor:
François Lokiec, Jean-François Bernaudin, Pierre Saintigny, S. Hugonin, D. Avenin, Eric Levy, Pierre Levy, Karine Beerblock, Joseph Gligorov, Anne Fajac, Frédéric Selle, Keyvan Rezai
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2010, 103 (4), pp.560-6. ⟨10.1038/sj.bjc.6605789⟩
British Journal of Cancer, 2010, 103 (4), pp.560-6. ⟨10.1038/sj.bjc.6605789⟩
British Journal of Cancer, Cancer Research UK, 2010, 103 (4), pp.560-6. ⟨10.1038/sj.bjc.6605789⟩
British Journal of Cancer, 2010, 103 (4), pp.560-6. ⟨10.1038/sj.bjc.6605789⟩
International audience; BACKGROUND: It can be hypothesised that inherited polymorphisms in the drug-transporter ABCB1 gene may interfere with interindividual variations in drug response in breast cancer patients. Docetaxel is a substrate for ABCB1 wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23bb301379cb88c155becc23b6309a4
https://hal.sorbonne-universite.fr/hal-00597585
https://hal.sorbonne-universite.fr/hal-00597585
Autor:
Woillard, Jean-Baptiste, Rerolle, Jean-Philippe, Picard, Nicolas, Rousseau, Annick, Guillaudeau, A., Munteanu, Etienne, Essig, Marie, Drouet, M., Le Meur, Yann, Marquet, Pierre
Publikováno v:
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, American Society for Clinical Pharmacology and Therapeutics, 2010, 88 (1), pp.95-100. ⟨10.1038/clpt.2010.62⟩
Clinical Pharmacology and Therapeutics, American Society for Clinical Pharmacology and Therapeutics, 2010, 88 (1), pp.95-100. ⟨10.1038/clpt.2010.62⟩
International audience; Cyclosporin A (CsA) is a substrate for cytochrome P450 3A and the efflux transporter P-glycoprotein (P-gp; ABCB1), both abundantly expressed in the kidney. In a long-term follow-up of a cohort of patients who had received kidn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1398::20d2d85e4ef794145a8b5f73f4e1da74
https://www.hal.inserm.fr/inserm-00462541/document
https://www.hal.inserm.fr/inserm-00462541/document