Zobrazeno 1 - 10
of 161
pro vyhledávání: '"MESH : NF-kappa B"'
Autor:
Florence Jeny, Jean-François Bernaudin, Dominique Valeyre, Marianne Kambouchner, Marina Pretolani, Hilario Nunes, Carole Planès, Valérie Besnard
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology, 2021, 12, pp.719009. ⟨10.3389/fimmu.2021.719009⟩
Frontiers in Immunology, Frontiers, 2021, 12, pp.719009. ⟨10.3389/fimmu.2021.719009⟩
Frontiers in Immunology
Frontiers in Immunology, 2021, 12, pp.719009. ⟨10.3389/fimmu.2021.719009⟩
Frontiers in Immunology, Frontiers, 2021, 12, pp.719009. ⟨10.3389/fimmu.2021.719009⟩
BackgroundMacrophages are pivotal cells in sarcoidosis. Monocytes-derived (MD) macrophages have recently been demonstrated to play a major role especially in pulmonary sarcoidosis. From inflammatory tissues to granulomas, they may be exposed to low o
Autor:
Izabela A. Rodenhuis-Zybert, Vinit Upasani, Bram M. ter Ellen, Mariana Ruiz-Silva, Rithy Choeung, Jill Moser, Mindaugas Pauzuolis, Denis R. St. Laurent, Tineke Cantaert, Philippe Dussart, José Alberto Aguilar-Briseño, Sothy Heng, Jolanda M. Smit
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3177. ⟨10.1038/s41467-020-16849-7⟩
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 11(1):3177. Nature Publishing Group
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3177. ⟨10.1038/s41467-020-16849-7⟩
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 11(1):3177. Nature Publishing Group
Vascular permeability and plasma leakage are immune-pathologies of severe dengue virus (DENV) infection, but the mechanisms underlying the exacerbated inflammation during DENV pathogenesis are unclear. Here, we demonstrate that TLR2, together with it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208ffd5bdf01936c1e26cb9d9b748d7d
https://hal-riip.archives-ouvertes.fr/pasteur-03221719
https://hal-riip.archives-ouvertes.fr/pasteur-03221719
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2020, 80 (4), pp.555-557. ⟨10.1016/j.molcel.2020.11.005⟩
Molecular Cell, Elsevier, 2020, 80 (4), pp.555-557. ⟨10.1016/j.molcel.2020.11.005⟩
Refers toJun-Kyu Byun, Mihyang Park, Seunghyeong Lee, Jae Won Yun, Jaebon Lee, Jae Sun Kim, Sung Jin Cho, Hui-Jeon Jeon, In-Kyu Lee, Yeon-Kyung Choi, Keun-Gyu ParkInhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fd7e505bf6bfaccc379abfd5f31abe
https://hal.archives-ouvertes.fr/hal-03382740/document
https://hal.archives-ouvertes.fr/hal-03382740/document
Autor:
Normand, Sylvain, Waldschmitt, Nadine, Neerincx, Andreas, Martinez-Torres, Ruben Julio, Chauvin, Camille, Couturier-Maillard, Aurelie, Boulard, Olivier, Cobret, Laetitia, Awad, Fawaz, Huot, Ludovic, Ribeiro-Ribeiro, Andre, Lautz, Katja, Ruez, Richard, Delacre, Myriam, Bondu, Clovis, Guilliams, Martin, Scott, Charlotte, Segal, Anthony, Amselem, Serge, Hot, David, Karabina, Sonia, Bohn, Erwin, Ryffel, Bernhard, Poulin, Lionel F, Kufer, Thomas A, Chamaillard, Mathias
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications, 2018, 9, pp.5338. ⟨10.1038/s41467-018-07750-5⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-07750-5⟩
Nature Communications, Nature Publishing Group, 2018, 9, pp.5338. ⟨10.1038/s41467-018-07750-5⟩
NATURE COMMUNICATIONS
Nature Communications
Nature Communications, 2018, 9, pp.5338. ⟨10.1038/s41467-018-07750-5⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-07750-5⟩
Nature Communications, Nature Publishing Group, 2018, 9, pp.5338. ⟨10.1038/s41467-018-07750-5⟩
NATURE COMMUNICATIONS
Mutations in the nucleotide-binding oligomerization domain protein 12 (NLRP12) cause recurrent episodes of serosal inflammation. Here we show that NLRP12 efficiently sequesters HSP90 and promotes K48-linked ubiquitination and degradation of NOD2 in r
Autor:
James M. Billingsley, Erica H. Parrish, Frank Kirchhoff, Thalia Garcia-Tellez, Nicolas Huot, Guido Silvestri, Ulrike Sauermann, Berit Neumann, Christina M. Stürzel, Gerald H. Learn, Steven E. Bosinger, Christiane Stahl-Hennig, Daniel Sauter, Beatrice H. Hahn, Dietmar Fuchs, Clement W. Gnanadurai, Michaela Müller-Trutwin, Simone Joas, Dominik Hotter, Edina Lump, Cristian Apetrei, Nicholas F. Parrish, Kerstin Mätz Rensing
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications, 2018, 9 (1), pp.1371-1371. ⟨10.1038/s41467-018-03762-3⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1371-1371. ⟨10.1038/s41467-018-03762-3⟩
Nature Communications
Nature Communications, 2018, 9 (1), pp.1371-1371. ⟨10.1038/s41467-018-03762-3⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1371-1371. ⟨10.1038/s41467-018-03762-3⟩
HIV-1 causes chronic inflammation and AIDS in humans, whereas related simian immunodeficiency viruses (SIVs) replicate efficiently in their natural hosts without causing disease. It is currently unknown to what extent virus-specific properties are re
Autor:
Mindy Tsai, Nicolas Gaudenzio, Axel Roers, See-Ying Tam, Yuko Kawakami, Pierre Chambon, Philipp Starkl, Dimitri Pirottin, Stephen J. Galli, Sophie El Abbas, Jinah Kim, Nadine Antoine, Fabrice Bureau, Oliwia W Zurek, Laurent L. Reber, Toshiaki Kawakami, Thomas Marichal, Riccardo Sibilano
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, 2016, 126 (12), pp.4497-4515. ⟨10.1172/JCI86359⟩
Journal of Clinical Investigation, 2016, 126 (12), pp.4497-4515. ⟨10.1172/JCI86359⟩
International audience; Epidermal keratinocytes form a structural and immune barrier that is essential for skin homeostasis. However, the mechanisms that regulate epidermal barrier function are incompletely understood. Here we have found that keratin
Autor:
Souraya Sayegh, Oula El Atat, Katy Diallo, Benjamin Rauwel, Yannick Degboé, Etienne Cavaignac, Arnaud Constantin, Alain Cantagrel, Viviane Trak-Smayra, Nada Alaaeddine, Jean-Luc Davignon
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, 2019, 10, pp.1482. ⟨10.3389/fimmu.2019.01482⟩
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, 2019, 10, pp.1482. ⟨10.3389/fimmu.2019.01482⟩
International audience; Introduction: Adipose-derived mesenchymal stem cells (ADSC) have been shown to have remarkable immune-modulating effects. However, their efficacy in clinical trials has yet to be fully demonstrated. This could be due to a lack
Autor:
Marta Mastrogiovanni, Paola Grazioli, Antonio Francesco Campese, Loretta Tuosto, Balbino Alarcón, Silvana Caristi, Cédric Favre, Nicla Porciello, Francesca Spadaro, Jacques A. Nunès, Isabella Screpanti, Martina Kunkl, Michela Muscolini, Aldo Borroto
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
CD28 superagonistic antibodies (CD28SAb) can preferentially activate and expand immunosuppressive regulatory T cells (Treg) in mice. However, pre-clinical trials assessing CD28SAbs for the therapy of autoimmune diseases reveal severe systemic inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29edf0332e8787c555c9b6ff4b29196e
https://hal.archives-ouvertes.fr/hal-01772994
https://hal.archives-ouvertes.fr/hal-01772994
Autor:
John DiGiovanni, Gyu Song, Lars Mecklenburg, Alexsandra Espejo, Richard D. Wood, Jean Louis Guénet, Jean Jaubert, Marcela Del Rio, Donna F. Kusewitt, Claudio J. Conti, Fernando Benavides, Lucía Martínez-Santamaría, Sharon Y.R. Dent, Eleonora Napoli, Cecilia R Giulivi, Carlos J. Perez, Brian M. Iritani, Mark T. Bedford
Publikováno v:
Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2015, 135 (12), pp.3133-3143. ⟨10.1038/jid.2015.314⟩
The Journal of investigative dermatology
The Journal of investigative dermatology, vol 135, iss 12
Journal of Investigative Dermatology, 2015, 135 (12), pp.3133-3143. ⟨10.1038/jid.2015.314⟩
Journal of Investigative Dermatology, Nature Publishing Group, 2015, 135 (12), pp.3133-3143. ⟨10.1038/jid.2015.314⟩
The Journal of investigative dermatology
The Journal of investigative dermatology, vol 135, iss 12
Journal of Investigative Dermatology, 2015, 135 (12), pp.3133-3143. ⟨10.1038/jid.2015.314⟩
International audience; Here we describe a spontaneous mutation in the Zdhhc13 (zinc finger, DHHC domain containing 13) gene (also called Hip14l), one of 24 genes encoding palmitoyl acyltransferase (PAT) enzymes in the mouse. This mutation (Zdhhc13lu
Autor:
Narimane Al Kattani, Antoine Kimmoun, Chaojie Wei, Nicolas Dessales, Pierre-Yves Marie, Julie Delemazure, Bruno Levy, Huguette Louis, Khodor Issa
Publikováno v:
Critical Care Medicine
Critical Care Medicine, Lippincott, Williams & Wilkins, 2015, 43 (9), pp.e332-e340. ⟨10.1097/CCM.0000000000001078⟩
Critical Care Medicine, Lippincott, Williams & Wilkins, 2015, 43 (9), pp.e332-e340. ⟨10.1097/CCM.0000000000001078⟩
International audience; OBJECTIVE:Preliminary experimental data suggest that selective β1-blockers may improve ex vivo cardiac function in animal sepsis. Currently, the effects of esmolol on in vivo cardiac function and on vascular function are unkn