Výsledky vyhledávání - "MESH : Myocardial Ischemia"

Therapeutic Benefit and Gene Network Regulation by Combined Gene Transfer of Apelin, FGF2, and SERCA2a into Ischemic Heart

Autor: Philippe Valet, Benoit Lebas, Bernard Masri, Pierre Sicard, Barbara Garmy-Susini, Jerome Roncalli, Fransky Hantelys, Françoise Pujol, Oksana Kunduzova, Anne-Catherine Prats, Xavier Chaufour, Edith Renaud-Gabardos, Angelo Parini, Florence Tatin, Denis Calise

Publikováno v: Molecular Therapy
Molecular Therapy, Nature Publishing Group, 2018, 26 (3), pp.902-916. ⟨10.1016/j.ymthe.2017.11.007⟩
Molecular Therapy, Cell Press, 2018, 26 (3), pp.902-916. ⟨10.1016/j.ymthe.2017.11.007⟩
Molecular Therapy, 2018, 26 (3), pp.902-916. ⟨10.1016/j.ymthe.2017.11.007⟩

International audience; Despite considerable advances in cardiovascular disease treatment, heart failure remains a public health challenge. In this context, gene therapy appears as an attractive approach, but clinical trials using single therapeutic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff05544b5df3c872bf90d9754a0bbb3
https://hal-univ-evry.archives-ouvertes.fr/hal-02393129

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Tissue kallikrein is required for the cardioprotective effect of Cyclosporin A in myocardial ischemia in the mouse

Autor: C. Richer, M.-P. Vincent, G. Youcef, François Alhenc-Gelas, Anne Pizard, Elise Belaidi, M. Clemessy, L. Fazal, Ludovic Waeckel, G. Zadigue, Michel Ovize

Publikováno v: Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2015, 94 (1), pp.22-29. ⟨10.1016/j.bcp.2015.01.007⟩
Biochemical Pharmacology, 2015, 94 (1), pp.22-29. ⟨10.1016/j.bcp.2015.01.007⟩

International audience; Clinical and experimental studies suggest that pharmacological postconditioning with Cyclosporin A (CsA) reduces infarct size in cardiac ischemia and reperfusion. CsA interacts with Cyclophilin D (CypD) preventing opening of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db81b18cd655788987a4450d868fcf43
https://doi.org/10.1016/j.bcp.2015.01.007

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Complement and its implications in cardiac ischemia/reperfusion: strategies to inhibit complement

Autor: Marc Fontaine, Tiphaine Monsinjon, Vincent Richard

Publikováno v: Fundamental and Clinical Pharmacology
Fundamental and Clinical Pharmacology, Wiley, 2001, 15 (5), pp.293-306. ⟨10.1046/j.1472-8206.2001.00040.x⟩

International audience; Although reperfusion of the ischemic myocardium is an absolute necessity to salvage tissue from eventual death, it is also associated with pathologic changes that represent either an acceleration of processes initiated during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd130a3958b9b48bbbe2b9779da24072
https://doi.org/10.1046/j.1472-8206.2001.00040.x

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Benefits of Endocardial and Multisite Pacing Are Dependent on the Type of Left Ventricular Electric Activation Pattern and Presence of Ischemic Heart Disease

Autor: Gerald Carr-White, Julian Bostock, Matthew Ginks, Anoop Shetty, Cliff Bucknall, Simon G. Duckett, Jaswinder Gill, C. Aldo Rinaldi, Pier D. Lambiase, Kawal Rhode, Peter Taggart, Christophe Leclercq, Janet L. Peacock, Reza Razavi

Publikováno v: Circulation: Arrhythmia and Electrophysiology
Circulation: Arrhythmia and Electrophysiology, 2012, 5 (5), pp.889-97. ⟨10.1161/CIRCEP.111.967505⟩
Circulation. Arrhythmia and electrophysiology
Circulation. Arrhythmia and electrophysiology, 2012, 5 (5), pp.889-97. ⟨10.1161/CIRCEP.111.967505⟩

Background— There is considerable heterogeneity in the myocardial substrate of patients undergoing cardiac resynchronization therapy (CRT), in particular in the etiology of heart failure and in the location of conduction block within the heart. Thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a619c062811501cbec95f0424e39c3
https://doi.org/10.1161/circep.111.967505

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Early pre-diabetic state alters adaptation of myocardial glucose metabolism during ischemia in rats

Autor: Stéphane Tanguy, Catherine Ghezzi, Joël de Leiris, Corinne Berthonneche, Sandrine Morel, Marie-Claire Toufektsian, Pascale Perret, François Boucher

Publikováno v: Molecular and Cellular Biochemistry
Molecular and Cellular Biochemistry, Springer Verlag, 2005, 272 (1-2), pp.9-17. ⟨10.1007/s11010-005-4778-1⟩

International audience; Pre-diabetic subjects with high insulin secretory capacity have double risk of cardiovascular disease compared with subjects who do not develop insulin-resistance. It is well established that the ability of the myocardium to i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affe6d765b998293a7b3897451e8d85c
https://doi.org/10.1007/s11010-005-4778-1

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Dual cardiac contractile effects of the alpha2-AMPK deletion in low-flow ischemia and reperfusion. : Role of AMPKa2 in basal and ischemic heart function

Autor: Benoit Viollet, Philippe Mateo, Sophie Vaulont, Elham Zarrinpashneh, J. A. Hoerter, Karla Carvajal, Frederic Joubert, Ondrej Szárszoi, Yoni Athea, Luc Bertrand, Brigitte Gillet, Renée Ventura-Clapier, Xavier Bigard

Publikováno v: American journal of physiology. Heart and circulatory physiology, Vol. 292, no.6, p. H3136-47 (2007)
AJP-Heart and Circulatory Physiology
AJP-Heart and Circulatory Physiology, American Physiological Society, 2007, 292 (6), pp.H3136-47. ⟨10.1152/ajpheart.00683.2006⟩
AJP-Heart and Circulatory Physiology, American Physiological Society, 2007, 292 (6), pp.H3136-47. 〈10.1152/ajpheart.00683.2006〉

Because the question “is AMP-activated protein kinase (AMPK) α2-isoform a friend or a foe in the protection of the myocardium against ischemia-reperfusion injury?” is still in debate, we studied the functional consequence of its deletion on the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2bfd4647ae05a821cc24b5b5414d4f
https://hdl.handle.net/2078.1/146096

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Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury

Autor: Davani S, CATHERINE VERGELY, Royer B, Bouhaddi M, Reyssie H, Rochette L, Jp, Kantelip

Publikováno v: Cellular and Molecular Biology
Cellular and Molecular Biology, R. Wegmann, 2006, 52 Suppl, pp.OL868-73
Cellular and Molecular Biology, OMICS International, 2006, 52 Suppl, pp.OL868-73
Europe PubMed Central

International audience; Previous studies indicate that adenosine supplementation or nitric oxide synthase (NOS) inhibition during reperfusion exert protective effects against myocardial ischemia-reperfusion (I/R) injury. We wanted to test the hypothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ea2155cc6f2885b0357ea0e58c963f7d
https://hal.archives-ouvertes.fr/hal-00452099

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A non-rigid registration approach for quantifying myocardial contraction in tagged MRI using generalized information measures

Autor: Francoise Preteux, Nicolas Rougon, Philippe Grenier, Caroline Petitjean, Philippe Cluzel

Publikováno v: Medical Image Analysis
Medical Image Analysis, Elsevier, 2005, 9 (4), pp.353-75. 〈10.1016/j.media.2005.01.005〉
Medical Image Analysis, Elsevier, 2005, 9 (4), pp.353-75. ⟨10.1016/j.media.2005.01.005⟩

International audience; We address the problem of quantitatively assessing myocardial function from tagged MRI sequences. We develop a two-step method comprising (i) a motion estimation step using a novel variational non-rigid registration technique

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03735381ed7055774f76c02a0a61d296
https://hal.archives-ouvertes.fr/hal-00673418

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[Cardiotoxicity of chemotherapies]

Autor: Marion, Castel, Fabien, Despas, Anouchka, Modesto, Céline, Gales, Benjamin, Honton, Michel, Galinier, Jean-Michel, Senard, Atul, Pathak

Publikováno v: La Presse medicale
La Presse medicale, Paris, Masson et Cie, 2013, 42 (1), pp.26-39. ⟨10.1016/j.lpm.2012.04.014⟩
La Presse medicale, 2013, 42 (1), pp.26-39. ⟨10.1016/j.lpm.2012.04.014⟩

International audience; The spectrum of chemotherapy's cardiac side effect of chemotherapy has expanded with the new combinations of cytotoxic and targeted therapies over the past 10 years. Moreover, cancer therapy administrated to "new" populations,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::53f76d3e8935fc9a57413945206abd29
https://www.hal.inserm.fr/inserm-00755341

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TGFβ-dependent epithelial-to-mesenchymal transition is required to generate cardiospheres from human adult heart biopsies

Autor: Ann Zeuner, Mark Mercola, Alessandro Giacomello, Francesco Angelini, Fabio Miraldi, Isotta Chimenti, Elisa Messina, Elvira Forte

Publikováno v: Stem Cells and Development
Stem Cells and Development, Mary Ann Liebert, 2012, 21 (17), pp.3081-90. ⟨10.1089/scd.2012.0277⟩

International audience; Autologous cardiac progenitor cells (CPCs) isolated as cardiospheres (CSps) represent a promising candidate for cardiac regenerative therapy. A better understanding of the origin and mechanisms underlying human CSps formation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138f946af331f34f681163363b9ed600
https://hal-riip.archives-ouvertes.fr/pasteur-00956822

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