Zobrazeno 1 - 10
of 112
pro vyhledávání: '"MESH : Mice, Mutant Strains"'
Autor:
David Briand, Aurore Besnard, Fabrice Chrétien, Mylène Fefeu, David Hardy, Paméla Gasse, Pierre Rocheteau, Fernando Arenzana-Seisdedos
Publikováno v:
Skeletal Muscle
Skeletal Muscle, 2019, 9 (1), pp.25. ⟨10.1186/s13395-019-0210-5⟩
Skeletal Muscle, Vol 9, Iss 1, Pp 1-15 (2019)
Skeletal Muscle, BioMed Central, 2019, 9 (1), pp.25. ⟨10.1186/s13395-019-0210-5⟩
Skeletal Muscle, 2019, 9 (1), pp.25. ⟨10.1186/s13395-019-0210-5⟩
Skeletal Muscle, Vol 9, Iss 1, Pp 1-15 (2019)
Skeletal Muscle, BioMed Central, 2019, 9 (1), pp.25. ⟨10.1186/s13395-019-0210-5⟩
BackgroundDuring muscle regeneration, the chemokine CXCL12 (SDF-1) and the synthesis of some specific heparan sulfates (HS) have been shown to be critical. CXCL12 activity has been shown to be heavily influenced by its binding to extracellular glycos
Autor:
Vincent Muczynski, Valérie Proulle, Peter J. Lenting, François Moreau, Paulette Legendre, Charlotte Kawecki, Gabriel Aymé, Caterina Casari, Olivier D. Christophe, Cécile V. Denis
Publikováno v:
Blood
Blood, American Society of Hematology, 2018, 132 (11), pp.1193-1197. ⟨10.1182/blood-2018-01-829523⟩
Blood, American Society of Hematology, 2018, 132 (11), pp.1193-1197. ⟨10.1182/blood-2018-01-829523⟩
International audience; Von Willebrand factor (VWF) modulates factor VIII (FVIII) clearance and the anti-FVIII immune response. Despite the high affinity that defines the FVIII/VWF interaction, association/dissociation kinetics dictates 2% to 5% FVII
Autor:
Jérôme De Seze, Thomas Nury, Gérard Lizard, Mustapha Cherkaoui-Malki, Quentin Raas, Mohamed El-Ayeb, Meryam Debbabi, Mohammad Samadi, Anne Vejux, Maryem Bezine, Rym Ben-Khalifa, Thibault Moreau
Publikováno v:
Chemistry and Physics of Lipids
Chemistry and Physics of Lipids, Elsevier, 2017, 207 (Pt B), pp.135-150. ⟨10.1016/j.chemphyslip.2017.03.006⟩
Chemistry and Physics of Lipids, Elsevier, 2017, 207 (Pt B), pp.135-150. ⟨10.1016/j.chemphyslip.2017.03.006⟩
International audience; Imbalance in the homeostasis of K+ ions has been reported to contribute to the pathogenesis of neurodegenerative diseases. 7-ketocholesterol (7KC), 24S-hydroxycholesterol (24S-OHC), and tetracosanoic acid (C24:0), often found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bdcec9f601194a1c3ddf921e1b1830
https://hal-riip.archives-ouvertes.fr/pasteur-01964971
https://hal-riip.archives-ouvertes.fr/pasteur-01964971
Autor:
Céline Genton, Adrien Kissenpfennig, Michael Mingueneau, Hans Acha-Orbea, Marie Malissen, Sylvie Richelme, Ying Wang, Pierre Perrin, Stéphane Chevrier, Bruno Lucas, James P. DiSanto, Bernard Malissen
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 180 (3), pp.1565-75. ⟨10.4049/jimmunol.180.3.1565⟩
Journal of Immunology, 2008, 180 (3), pp.1565-75. ⟨10.4049/jimmunol.180.3.1565⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 180 (3), pp.1565-75. 〈10.4049/jimmunol.180.3.1565〉
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 180 (3), pp.1565-75. ⟨10.4049/jimmunol.180.3.1565⟩
Journal of Immunology, 2008, 180 (3), pp.1565-75. ⟨10.4049/jimmunol.180.3.1565⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 180 (3), pp.1565-75. 〈10.4049/jimmunol.180.3.1565〉
Mutant mice where tyrosine 136 of linker for activation of T cells (LAT) was replaced with a phenylalanine (LatY136F mice) develop a fast-onset lymphoproliferative disorder involving polyclonal CD4 T cells that produce massive amounts of Th2 cytokine
Autor:
Michel Cogné, Yves Denizot, Christelle Vincent-Fabert, Pauline Rouaud, Eric Pinaud, Rémi Fiancette
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (11), pp.8356-60. ⟨10.1074/jbc.M112.341024⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (11), pp.8356-60. ⟨10.1074/jbc.M112.341024⟩
International audience; V(D)J recombination occurs during the antigen-independent early steps of B-cell ontogeny. Multiple IgH cis-regulatory elements control B-cell ontogeny. IGCR1 (intergenic control region 1), the DQ52 promoter/enhancer, and the i
Autor:
Jacques Ohayon, Nicolas Mesnier, Jackub Toczek, Alexis Broisat, Laurent Riou, Philippe Tracqui
Publikováno v:
Journal of Structural Biology
Journal of Structural Biology, Elsevier, 2011, 174 (1), pp.115-23. ⟨10.1016/j.jsb.2011.01.010⟩
Journal of Structural Biology, Elsevier, 2011, 174 (1), pp.115-23. ⟨10.1016/j.jsb.2011.01.010⟩
International audience; Several studies have suggested that evolving mechanical stresses and strains drive atherosclerotic plaque development and vulnerability. Especially, stress distribution in the plaque fibrous capsule is an important determinant
Autor:
Vicente C. Quintanilla, Cecilia R Giulivi, Donna F. Kusewitt, Jimi L. Brandon, Fernando Benavides, Jean Jaubert, Kirstin F. Barnhart, Irma B. Gimenez-Conti, Nancy W. Otto, Catherine Ross-Inta, John DiGiovanni, Claudio J. Conti, Carlos J. Perez, Jean-Louis Guénet, Isabelle Aubin
Publikováno v:
American Journal of Pathology
American Journal of Pathology, 2010, 177 (4), pp.1958-1968. ⟨10.2353/ajpath.2010.100118⟩
American Journal of Pathology, American Society for Investigative Pathology, 2010, 177 (4), pp.1958-1968. ⟨10.2353/ajpath.2010.100118⟩
American Journal of Pathology, 2010, 177 (4), pp.1958-1968. ⟨10.2353/ajpath.2010.100118⟩
American Journal of Pathology, American Society for Investigative Pathology, 2010, 177 (4), pp.1958-1968. ⟨10.2353/ajpath.2010.100118⟩
International audience; Citrullinemia type I (CTLN1, OMIM# 215700) is an inherited urea cycle disorder that is caused by an argininosuccinate synthetase (ASS) enzyme deficiency. In this report, we describe two spontaneous hypomorphic alleles of the m
Autor:
Fred Sablitzky, Danièle Mathieu, Philippe Couttet, Christiane Dohet, Rawan El-Hajj, Valérie Pinet, Nelly Pirot, Virginie Deleuze
Publikováno v:
Blood
Blood, American Society of Hematology, 2010, 115 (25), pp.5270-9. ⟨10.1182/blood-2010-03-275651⟩
Blood, American Society of Hematology, 2010, 115 (25), pp.5270--9. ⟨10.1182/blood-2010-03-275651⟩
Blood, American Society of Hematology, 2010, 115 (25), pp.5270-9. ⟨10.1182/blood-2010-03-275651⟩
Blood, American Society of Hematology, 2010, 115 (25), pp.5270--9. ⟨10.1182/blood-2010-03-275651⟩
The 2 related basic helix loop helix genes, LYL1 and TAL-1 are active in hematopoietic and endothelial lineages. While Tal-1 is essential for both hematopoietic and vascular development, the role of Lyl1 appears to be distinct as deficient mice are v
Autor:
Elisa Caberlotto, Jean-Yves Tinevez, Christine Petit, Christophe Houbron, Guy P. Richardson, Emilie Bizard, Pascal Martin, Vincent Michel, Nicolas Michalski, Alexander F. J. van Aken, Gaelle M. Lefèvre, Jean-Pierre Hardelin, Corné J. Kros, Dominique Weil
Publikováno v:
Pflügers Archiv European Journal of Physiology
Pflügers Archiv European Journal of Physiology, Springer Verlag, 2009, 459 (1), pp.115-130. ⟨10.1007/s00424-009-0711-x⟩
Pflügers Archiv European Journal of Physiology, 2009, 459 (1), pp.115-130. ⟨10.1007/s00424-009-0711-x⟩
Pflugers Archiv
Pflügers Archiv European Journal of Physiology, Springer Verlag, 2009, 459 (1), pp.115-130. ⟨10.1007/s00424-009-0711-x⟩
Pflügers Archiv European Journal of Physiology, 2009, 459 (1), pp.115-130. ⟨10.1007/s00424-009-0711-x⟩
Pflugers Archiv
We assessed the involvement of harmonin-b, a submembranous protein containing PDZ domains, in the mechanoelectrical transduction machinery of inner ear hair cells. Harmonin-b is located in the region of the upper insertion point of the tip link that
Autor:
Enrique Aguado, Amandine Sansoni, Arkadiusz Miazek, Michael Mingueneau, Marie Malissen, Elodie Bertosio, Pierre Perrin, Bernard Malissen, Adrien Kissenpfennig, Cristel Archambaud, Sylvie Richelme, Romain Roncagalli, Claude Grégoire, Ying Wang, Richard M. Locksley
Publikováno v:
Immunity
Immunity, Elsevier, 2009, 31 (2), pp.197-208. ⟨10.1016/j.immuni.2009.05.013⟩
Immunity; Vol 31
Immunity, 2009, 31 (2), pp.197-208. ⟨10.1016/j.immuni.2009.05.013⟩
Mingueneau, M, Roncagalli, R, Grégoire, C, Kissenpfennig, A, Miazek, A, Archambaud, C, Wang, Y, Perrin, P, Bertosio, E, Sansoni, A, Richelme, S, Locksley, R M & Aguado, E 2009, ' Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. ', Immunity, vol. 31(2), no. 2, pp. 197-208 . https://doi.org/10.1016/j.immuni.2009.05.013
Immunity, Elsevier, 2009, 31 (2), pp.197-208. ⟨10.1016/j.immuni.2009.05.013⟩
Immunity; Vol 31
Immunity, 2009, 31 (2), pp.197-208. ⟨10.1016/j.immuni.2009.05.013⟩
Mingueneau, M, Roncagalli, R, Grégoire, C, Kissenpfennig, A, Miazek, A, Archambaud, C, Wang, Y, Perrin, P, Bertosio, E, Sansoni, A, Richelme, S, Locksley, R M & Aguado, E 2009, ' Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. ', Immunity, vol. 31(2), no. 2, pp. 197-208 . https://doi.org/10.1016/j.immuni.2009.05.013
International audience; Despite compromised T cell antigen receptor (TCR) signaling, mice in which tyrosine 136 of the adaptor linker for activation of T cells (LAT) was constitutively mutated (Lat(Y136F) mice) accumulate CD4(+) T cells that trigger