Výsledky vyhledávání - "MESH : Mesothelioma"

Five years update on relationships between malignant pleural mesothelioma and exposure to asbestos and other elongated mineral particles

Autor: Pascal Andujar, Marie-Claude Jaurand, Didier Jean, Patrick Brochard, Aude Lacourt, Jean-Claude Pairon

Publikováno v: Journal of Toxicology and Environmental Health, Part B: Critical Reviews
Journal of Toxicology and Environmental Health, Part B: Critical Reviews, Taylor & Francis, 2016, 19 (5-6), pp.151-172. ⟨10.1080/10937404.2016.1193361⟩

International audience; Despite the reduction of global asbestos consumption and production due to the ban or restriction of asbestos uses in more than 50 countries since the 1970s, malignant mesothelioma remains a disease of concern. Asbestos is sti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596dd84e6cb54b98dd404570be86013d
https://doi.org/10.1080/10937404.2016.1193361

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Assessment of signaling pathway inhibitors and identification of predictive biomarkers in malignant pleural mesothelioma

Autor: Marie-Claude Jaurand, Robin Tranchant, Jessica Zucman-Rossi, Clément Meiller, Didier Jean, Lisa Quetel, Julien de Wolf, Leanne de Koning, François Montagne, Françoise Le Pimpec-Barthes

Publikováno v: Lung Cancer
Lung Cancer, Elsevier, 2018, 126, pp.15-24. ⟨10.1016/j.lungcan.2018.10.015⟩
Lung Cancer, 2018, 126, pp.15-24. ⟨10.1016/j.lungcan.2018.10.015⟩

International audience; OBJECTIVES:Malignant pleural mesothelioma (MPM) is an aggressive tumor with limited therapeutic options, requiring the development of efficient targeted therapies based on molecular phenotype of the tumor and to identify predi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5907b192ad58c6401d8a73ec0a34452
https://www.hal.inserm.fr/inserm-02478609

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Mesotheliomas in Genetically Engineered Mice Unravel Mechanism of Mesothelial Carcinogenesis

Autor: Didier Jean, Marie-Claude Jaurand

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2018, 19 (8), pp.2191. ⟨10.3390/ijms19082191⟩
International Journal of Molecular Sciences, 2018, 19 (8), pp.2191. ⟨10.3390/ijms19082191⟩
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2191 (2018)

International audience; Malignant mesothelioma (MM), a rare and severe cancer, mainly caused as a result of past-asbestos exposure, is presently a public health concern. Current molecular studies aim to improve the outcome of the disease, providing e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f1d726e36e78ffef14c58f6b1b6899
https://www.hal.inserm.fr/inserm-02478607

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CLI-MAT. Matrice appliquée pour le clinicien dans l’aide au repérage de l’exposition professionnelle à l’amiante et à la silice cristalline des patients atteints de cancer pulmonaire ou de mésothéliome

Autor: Lorentz, Elise

Publikováno v: Médecine humaine et pathologie. 2018

Introduction: in a context where lung cancer is underreported as occupational diseases, the aim was to study the validity of an application based on silica and asbestos job-exposure matrices in screening occupational exposure. Methods: between novemb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2592::d4924a08d8c044d2f4ad1f410e2539ca
https://dumas.ccsd.cnrs.fr/dumas-01903595/document

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Hétérogénéité moléculaire des mésothéliomes pleuraux malins

Autor: Robin Tranchant, Didier Jean, Marie-Claude Jaurand, François Montagne

Publikováno v: Bulletin du Cancer
Bulletin du Cancer, John Libbey Eurotext, 2018, 105 (1), pp.35-45. ⟨10.1016/j.bulcan.2017.11.007⟩
Bulletin du Cancer, 2018, 105 (1), pp.35-45. ⟨10.1016/j.bulcan.2017.11.007⟩

Malignant pleural mesothelioma (MPM) is predominantly an occupational cancer, most often linked to asbestos exposure. Malignant pleural mesothelioma prognosis is poor with a short survival median, due to the aggressiveness of tumor cells and the weak

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac5afa9d872a0382a7f7505a9205abc
https://www.hal.inserm.fr/inserm-02478606

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Hétérogénéité moléculaire des mésothéliomes pleuraux malins

Autor: Robin, Tranchant, François, Montagne, Marie-Claude, Jaurand, Didier, Jean

Publikováno v: Bulletin du Cancer
Bulletin du Cancer, John Libbey Eurotext, 2018, 105 (1), pp.35-45. ⟨10.1016/j.bulcan.2017.11.007⟩

International audience; Malignant pleural mesothelioma (MPM) is predominantly an occupational cancer, most often linked to asbestos exposure. Malignant pleural mesothelioma prognosis is poor with a short survival median, due to the aggressiveness of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9b08b11e91ac037ee0bfb03a160b609f
https://www.hal.inserm.fr/inserm-02478606

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Co-occurring Mutations of Tumor Suppressor Genes, LATS2 and NF2 , in Malignant Pleural Mesothelioma

Autor: Françoise Le Pimpec-Barthes, Marie-Claude Jaurand, Jessica Zucman-Rossi, Leanne De Koning, Anne Tallet, Lisa Quetel, Clément Meiller, Aurélien de Reyniès, Annie Renier, Robin Tranchant, Didier Jean

Publikováno v: Clinical Cancer Research
Clinical Cancer Research, 2017, 23 (12), pp.3191-3202. ⟨10.1158/1078-0432.CCR-16-1971⟩
Clinical Cancer Research, American Association for Cancer Research, 2017, 23 (12), pp.3191-3202. ⟨10.1158/1078-0432.CCR-16-1971⟩

Purpose: To better define malignant pleural mesothelioma (MPM) heterogeneity and identify molecular subtypes of MPM, we focus on the tumor suppressor gene LATS2, a member of the Hippo signaling pathway, which plays a key role in mesothelial carcinoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84680edb50cc3830526188a96f3c5972
https://www.hal.inserm.fr/inserm-02478604/document

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Choice of rating method for assessing occupational asbestos exposure: study for compensation purposes in France.: Method for occupational exposure assessment

Autor: Celine, Gramond, Patrick, Rolland, Aude, Lacourt, Stephane, Ducamp, Soizick, Chamming's, Yvon, Creau, Michel, Hery, Jacques, Laureillard, Brahim, Mohammed-Brahim, Ewa, Orlowski, Christophe, Paris, Jean-Claude, Pairon, Marcel, Goldberg, Patrick, Brochard, S, Chamming's

Publikováno v: American Journal of Industrial Medicine
American Journal of Industrial Medicine, Wiley, 2012, 55 (5), pp.440-9. ⟨10.1002/ajim.22008⟩

Background In the course of setting up the National Mesothelioma Surveillance Program (PNSM), established in France in 1998, the question arose as to the most suitable method of assessing occupational exposure. The aim of this study was to define the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ccc1a19435ce1d1eb1302cb6926079
https://doi.org/10.1002/ajim.22008

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[Follow-up of subjects occupationally exposed to asbestos, what are the objectives, the benefits, and the possible risks?]

Autor: Dalphin, J.-C.

Publikováno v: Revue des Maladies Respiratoires
Revue des Maladies Respiratoires, Elsevier Masson, 2011, 28 (10), pp.1230-40. 〈10.1016/j.rmr.2011.06.015〉
Revue des Maladies Respiratoires, Elsevier Masson, 2011, 28 (10), pp.1230-40. ⟨10.1016/j.rmr.2011.06.015⟩

International audience; The follow-up of workers occupationally exposed to asbestos has two possible beneficial effects: (1) individually, both medical by screening for diseases related to asbestos and social by notification of occupational disease a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ac6880687e8c213de8b6dfbe4c0cd478
https://hal.archives-ouvertes.fr/hal-00759170

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