Zobrazeno 1 - 10 of 318 pro vyhledávání: '"MESH : Lymphocyte Activation"'
1
CD4+ T cells that help B cells – a proposal for uniform nomenclature
Autor: Stuart G. Tangye, Nicolas Fazilleau, Joe Craft, Stephanie C. Eisenbarth, Carola G. Vinuesa, Dirk Baumjohann, Cindy S. Ma, Michelle A. Linterman
Publikováno v: Trends Immunol
Trends in Immunology
Trends in Immunology, 2021, 42 (8), pp.658-669. ⟨10.1016/j.it.2021.06.003⟩
International audience; T follicular helper (Tfh) cells cognately guide differentiation of antigen-primed B cells in secondary lymphoid tissues. 'Tfh-like' populations not expressing the canonical Tfh cell transcription factor BCL6 have also been des
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d19aad2e8378d37dac5e6abecb1fe44
https://doi.org/10.1016/j.it.2021.06.003
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2
Fine Analysis of Lymphocyte Subpopulations in SARS-CoV-2 Infected Patients: Differential Profiling of Patients With Severe Outcome
Autor: Giovanna Clavarino, Corentin Leroy, Olivier Epaulard, Tatiana Raskovalova, Antoine Vilotitch, Martine Pernollet, Chantal Dumestre-Pérard, Federica Defendi, Marion Le Maréchal, Audrey Le Gouellec, Pierre Audoin, Jean-Luc Bosson, Pascal Poignard, Matthieu Roustit, Marie-Christine Jacob, Jean-Yves Cesbron
Publikováno v: Frontiers in Immunology
Frontiers in Immunology, 2022, 13, pp.889813. ⟨10.3389/fimmu.2022.889813⟩
COVID-19 is caused by the human pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has resulted in widespread morbidity and mortality. CD4+ T cells, CD8+ T cells and neutralizing antibodies all contribute to control SARS-CoV-2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d2e492b6939ee59d9cae1728affc94
https://pubmed.ncbi.nlm.nih.gov/35911748
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3
Cell-mediated immunity to NAGLU transgene following intracerebral gene therapy in children with Mucopolysaccharidosis type IIIB syndrome
Autor: Gougeon, Marie-Lise, Poirier-Beaudouin, Béatrice, Ausseil, Jérome, Zérah, Michel, Artaud, Cécile, Heard, Jean-Michel, Deiva, Kumaran, Tardieu, Marc
Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2021, 12, pp.655478. ⟨10.3389/fimmu.2021.655478⟩
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, 2021, 12, pp.655478. ⟨10.3389/fimmu.2021.655478⟩
International audience; Mucopolysaccharidosis type IIIB syndrome (Sanfilippo disease) is a rare autosomic recessif disorder caused by mutations in the α-N-acetylglucosaminidase (NAGLU) gene coding for a lysosomal enzyme, leading to neurodegeneration
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::264181ddb1d95ef2cdef9ef8f1850cc3
https://hal.sorbonne-universite.fr/hal-03241952/file/fimmu-12-655478.pdf
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4
Dichotomous metabolic networks govern human ILC2 proliferation and function
Autor: Carys A. Croft, James P. Di Santo, Antonia Cama, Solenne Marie, Carmen Buchrieser, Davide Topazio, Olimpia Musumeci, Valerie Dardalhon, Laura Surace, Naomi Taylor, Jean-Marc Doisne, Vincent Guillemot, Natalia Petrosemoli, Pedro Escoll, Ido Amit, Anna Thaller
Publikováno v: Nature Immunology
Nature Immunology, 2021, 22 (11), pp.1367-1374. ⟨10.1038/s41590-021-01043-8⟩
Nature Immunology, Nature Publishing Group, 2021, 22 (11), pp.1367-1374. ⟨10.1038/s41590-021-01043-8⟩
Group 2 innate lymphoid cells (ILC2s) represent innate homologs of type 2 helper T cells (TH2) that participate in immune defense and tissue homeostasis through production of type 2 cytokines. While T lymphocytes metabolically adapt to microenvironme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e072b6d889432eb5d0e60a3fe6f3aa3b
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5
The activation trajectory of plasmacytoid dendritic cells in vivo during a viral infection
Autor: Jean-Luc Davignon, Karima Naciri, Rabie Chelbi, Gilles Bessou, Chuang Dong, Nils Collinet, Michael Valente, Geoffray Brelurut, Pierre Milpied, Abdenour Abbas, Morgane Thomas-Chollier, Noudjoud Attaf, Thien-Phong Vu Manh, Inaki Cervera-Marzal, Alexandra-Chloé Villani, Benjamin Rauwel, Denis Thieffry, Marc Dalod, Elena Tomasello
Publikováno v: Nature Immunology
Nature Immunology, Nature Publishing Group, 2020, 21 (9), pp.983-997. ⟨10.1038/s41590-020-0731-4⟩
Nature Immunology, 2020, 21 (9), pp.983-997. ⟨10.1038/s41590-020-0731-4⟩
Nature immunology
International audience; Plasmacytoid dendritic cells (pDCs) are a major source of type I interferon (IFN-I). What other functions pDCs exert in vivo during viral infections is controversial, and more studies are needed to understand their orchestrati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd76519d3ec2c2f1de126656bc2665f9
https://hal.archives-ouvertes.fr/hal-02980944/file/2020_11_30_Abbas_et_al_2020_accepted_manuscript_for_HAL_small_size.pdf
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6
Les rétrovirus endogènes : un rôle clé dans la programmation des lymphocytes T CD4
Autor: Véronique Adoue, Olivier Joffre
Publikováno v: médecine/sciences
médecine/sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩
médecine/sciences, EDP Sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩
Upon priming by dendritic cells, naïve CD4 T lymphocytes are exposed to distinct molecular environments depending on the nature of the pathological stimulus. In response, they mobilize different gene networks that establish lineage-specific developm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d8bbf56b7f22d0ec282cc76e4db22f
https://doi.org/10.1051/medsci/2020022
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7
Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity
Autor: James M. Billingsley, Erica H. Parrish, Frank Kirchhoff, Thalia Garcia-Tellez, Nicolas Huot, Guido Silvestri, Ulrike Sauermann, Berit Neumann, Christina M. Stürzel, Gerald H. Learn, Steven E. Bosinger, Christiane Stahl-Hennig, Daniel Sauter, Beatrice H. Hahn, Dietmar Fuchs, Clement W. Gnanadurai, Michaela Müller-Trutwin, Simone Joas, Dominik Hotter, Edina Lump, Cristian Apetrei, Nicholas F. Parrish, Kerstin Mätz Rensing
Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications, 2018, 9 (1), pp.1371-1371. ⟨10.1038/s41467-018-03762-3⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1371-1371. ⟨10.1038/s41467-018-03762-3⟩
HIV-1 causes chronic inflammation and AIDS in humans, whereas related simian immunodeficiency viruses (SIVs) replicate efficiently in their natural hosts without causing disease. It is currently unknown to what extent virus-specific properties are re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1197f84a4b83f3d4c65fd5483900fedf
http://link.springer.com/article/10.1038/s41467-018-03762-3
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8
A non-conserved amino acid variant regulates differential signalling between human and mouse CD28
Autor: Marta Mastrogiovanni, Paola Grazioli, Antonio Francesco Campese, Loretta Tuosto, Balbino Alarcón, Silvana Caristi, Cédric Favre, Nicla Porciello, Francesca Spadaro, Jacques A. Nunès, Isabella Screpanti, Martina Kunkl, Michela Muscolini, Aldo Borroto
Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications, 2018, 9 (1), pp.1080. ⟨10.1038/s41467-018-03385-8⟩
Digital.CSIC. Repositorio Institucional del CSIC
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CD28 superagonistic antibodies (CD28SAb) can preferentially activate and expand immunosuppressive regulatory T cells (Treg) in mice. However, pre-clinical trials assessing CD28SAbs for the therapy of autoimmune diseases reveal severe systemic inflamm
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29edf0332e8787c555c9b6ff4b29196e
https://hal.archives-ouvertes.fr/hal-01772994
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9
The Juxtamembrane Domain of Butyrophilin BTN3A1 Controls Phosphoantigen-Mediated Activation of Human Vγ9Vδ2 T Cells
Autor: Peigné, Cassie-Marie, Léger, Alexandra, Gesnel, Marie-Claude, Konczak, Fabienne, Olive, Daniel, Bonneville, Marc, Breathnach, Richard, Scotet, Emmanuel, Leger, Alexandra
Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2017, 198 (11), pp.4228-4234. ⟨10.4049/jimmunol.1601910⟩
Journal of Immunology, 2017, 198 (11), pp.4228-4234. ⟨10.4049/jimmunol.1601910⟩
Vγ9Vδ2 T lymphocytes are the major human peripheral γδ T cell subset, with broad reactivity against stressed human cells, including tumor cells. Vγ9Vδ2 T cells are specifically activated by small phosphorylated metabolites called phosphoantigen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b7582d2331444f78a5f34be11f4fed
https://doi.org/10.4049/jimmunol.1601910
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10
Developmental options and functional plasticity of innate lymphoid cells
Autor: Christian A. J. Vosshenrich, Ai Ing Lim, Thomas Verrier, James P. Di Santo
Publikováno v: Current Opinion in Immunology
Current Opinion in Immunology, Elsevier, 2017, 44, pp.61-68. ⟨10.1016/j.coi.2017.03.010⟩
Current Opinion in Immunology, 2017, 44, pp.61-68. ⟨10.1016/j.coi.2017.03.010⟩
International audience; Innate lymphoid cells (ILCs) are lineage- and antigen receptor-negative lymphocytes including natural killer (NK) cells and at least three distinguishable cell subsets (ILC1, ILC2, ILC3) that rapidly produce cytokines (IFN-γ,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c35a89effa1835b561e736076b889a
https://doi.org/10.1016/j.coi.2017.03.010
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