Výsledky vyhledávání - "MESH : Jurkat Cells"

The fully synthetic glycopeptide MAG-Tn3 therapeutic vaccine induces tumor-specific cytotoxic antibodies in breast cancer patients

Autor: Cecile Artaud, Marie-Paule Sablin, Jacques Medioni, Pierre Rosenbaum, Sylvie Bay, Olivier Tredan, Christelle Ganneau, Suzette Delaloge, Delphine Loirat, Mario Campone, François Pein, Claude Leclerc, Andrea Varga, Carole Gourmelon

Publikováno v: Cancer Immunology, Immunotherapy
Cancer Immunology, Immunotherapy, Springer Verlag, 2020, 69 (5), pp.703-716. ⟨10.1007/s00262-020-02503-0⟩
Cancer Immunology, Immunotherapy, 2020, 69 (5), pp.703-716. ⟨10.1007/s00262-020-02503-0⟩

International audience; Cancer is one of the main causes of mortality worldwide and a major public health concern. Among various strategies, therapeutic vaccines have been developed to stimulate anti-tumoral immune responses. However, in spite of ext

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78818bcefd52ce7613a01537f7dfaf47
https://hal-pasteur.archives-ouvertes.fr/pasteur-03329313

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Characterization of neutralizing antibodies reacting with the 213-224 amino-acid segment of human galectin-9

Autor: Lhuillier, Claire, Barjon, Clément, Baloche, Valentin, Niki, Toshiro, Gelin, Aurore, Mustapha, Rami, Claër, Laetitia, Hoos, Sylviane, Chiba, Yoichi, Ueno, Masaki, Hirashima, Mitsuomi, Wei, Ming, Moralès, Olivier, Raynal, Bertrand, Delhem, Nadira, Dellis, Olivier, Busson, Pierre

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2018, 13 (9), pp.e0202512. ⟨10.1371/journal.pone.0202512⟩
PLoS ONE, 2018, 13 (9), pp.e0202512. ⟨10.1371/journal.pone.0202512⟩

International audience; Extra-cellular galectin-9 (gal-9) is an immuno-modulatory protein with predominant immuno-suppressive effects. Inappropriate production of gal-9 has been reported in several human malignancies and viral diseases like nasophary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::36aec931ee5240029bd568e3833ad99b
https://hal.archives-ouvertes.fr/hal-02414847

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Caractérisation d'anticorps neutralisants réagissant avec le segment des acides aminés 213-224 de la galectine-9 humaine

Autor: Claire Lhuillier, Clément Barjon, Valentin Baloche, Toshiro Niki, Aurore Gelin, Rami Mustapha, Laetitia Claër, Sylviane Hoos, Yoichi Chiba, Masaki Ueno, Mitsuomi Hirashima, Ming Wei, Olivier Morales, Bertrand Raynal, Nadira Delhem, Olivier Dellis, Pierre Busson

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2018, 13 (9), pp.e0202512. ⟨10.1371/journal.pone.0202512⟩
PLoS ONE, Vol 13, Iss 9, p e0202512 (2018)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cb53f9abe50394d89b97efe66af27424
https://pubmed.ncbi.nlm.nih.gov/30204750

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Cyclophilin A enables specific HIV-1 Tat palmitoylation and accumulation in uninfected cells

Autor: Chopard, Christophe, Tong, Phuoc Bao Viet, Toth, Petra, Schatz, Malvina, Yezdi, Hocine, Debaisieux, Solène, Mettling, Clément, Gross, Antoine, Pugniere, Martine, Tu, Annie, Strub, Jean Marc, Mesnard, Jean-Michel, Vitale, Nicolas, Beaumelle, Bruno

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications, 2018, 9 (1), pp.2251. ⟨10.1038/s41467-018-04674-y⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.2251. ⟨10.1038/s41467-018-04674-y⟩
Nature Communications, 2018, 9
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-04674-y⟩

Most HIV-1 Tat is unconventionally secreted by infected cells following Tat interaction with phosphatidylinositol (4,5) bisphosphate (PI(4,5)P2) at the plasma membrane. Extracellular Tat is endocytosed by uninfected cells before escaping from endosom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9ac8b602dd05d826b05f6c2a35180a46
https://hal.archives-ouvertes.fr/hal-02655916

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CD4+ T cell-mediated HLA class II cross-restriction in HIV controllers

Autor: Daniela Benati, Moran Galperin, Jamie Rossjohn, Lisa Ciacchi, Amandine Decroos, Lisa A. Chakrabarti, Hugh H. Reid, Dhilshan Jayasinghe, Stephanie Gras, Madhura Mukhopadhyay, Li Lynn Tan, C. Farenc

Publikováno v: Science Immunology
Science Immunology, American Association for the Advancement of Science, 2018, 3 (24), pp.eaat0687. ⟨10.1126/sciimmunol.aat0687⟩
Science Immunology, 2018, 3 (24), pp.eaat0687. ⟨10.1126/sciimmunol.aat0687⟩

International audience; Rare individuals, termed HIV controllers, spontaneously control HIV infection by mounting efficient T cell responses against the virus. Protective CD4+ T cell responses from HIV controllers involve high-affinity public T cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1364c6d98ab51af27681c72e4a2ec1
https://hdl.handle.net/11380/1169081

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Identification of novel substrates of Shigella T3SA through analysis of its virulence plasmid-encoded secretome

Autor: Laurie Pinaud, Philippe J. Sansonetti, Mariana L. Ferrari, Armelle Phalipon, Robin C. Friedman, Martin von Bergen, François-Xavier Campbell-Valois, Nico Jehmlich

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2017, 12 (10), pp.e0186920. ⟨10.1371/journal.pone.0186920⟩
PLoS ONE, 2017, 12 (10), pp.e0186920. ⟨10.1371/journal.pone.0186920⟩
PLoS ONE, Vol 12, Iss 10, p e0186920 (2017)

International audience; Many human Gram-negative bacterial pathogens express a Type Three Secretion Apparatus (T3SA), including among the most notorious Shigella spp., Salmonella enterica, Yersinia enterocolitica and enteropathogenic Escherichia coli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a283aaa40baee00b5e29db4e8884a449
https://hal-pasteur.archives-ouvertes.fr/pasteur-02874891/file/journal.pone.0186920.pdf

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IRX-2, a novel immunotherapeutic, protects human T cells from tumor-induced cell death

Autor: Theresa L. Whiteside, Marta Szajnik, H Brandwein, Miroslaw J. Szczepanski, J W Hadden, J Han, K Signorelli, K Quadrini, Malgorzata Czystowska

Publikováno v: Cell Death and Differentiation
Cell Death and Differentiation, 2009, 16 (5), pp.708-18. ⟨10.1038/cdd.2008.197⟩
Cell Death and Differentiation, Nature Publishing Group, 2009, 16 (5), pp.708-18. ⟨10.1038/cdd.2008.197⟩
Cell Death and Differentiation, Nature Publishing Group, 2009, 16 (5), pp.708-18. 〈10.1038/cdd.2008.197〉

International audience; IRX-2 is a cytokine-based biologic agent that has the potential to enhance antitumor immune responses. We investigated whether IRX-2 can protect T cells from tumor-induced apoptosis. Tumor-derived microvesicles (MV) expressing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4405aefc4179838cd033255d4555d7ba
https://doi.org/10.1038/cdd.2008.197

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Shaping mycolactone for therapeutic use against inflammatory disorders

Autor: Sophie Hidalgo-Lucas, Georges Bismuth, Jean-François Bisson, Laure Guenin-Macé, Sarah Saint-Auret, Cédric Tresse, Fabien Le Chevalier, Caroline Demangel, Pierre Bruhns, Ludivine Baron, Nicolas Blanchard, Friederike Jönsson, Anne-Caroline Chany

Publikováno v: Science Translational Medicine
Science Translational Medicine, 2015, 7 (289), pp.289ra85-289ra85. ⟨10.1126/scitranslmed.aab0458⟩
Science Translational Medicine, American Association for the Advancement of Science, 2015, 7 (289), pp.289ra85-289ra85. 〈10.1126/scitranslmed.aab0458〉
Science Translational Medicine, American Association for the Advancement of Science, 2015, 7 (289), pp.289ra85-289ra85. ⟨10.1126/scitranslmed.aab0458⟩

International audience; Inflammation adversely affects the health of millions of people worldwide, and there is an unmet medical need for better anti-inflammatory drugs. We evaluated the therapeutic interest of mycolactone, a polyketide-derived macro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515e3e0e604c57dc804f3e80b4b4c2c8
https://doi.org/10.1126/scitranslmed.aab0458

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HOX11L2/TLX3 is transcriptionally activated through T-cell regulatory elements downstream of BCL11B as a result of the t(5;14)(q35;q32)

Autor: Virginie Penard-Lacronique, Isabelle André-Schmutz, Xin-Ying Su, Roland Berger, Paola Ballerini, Claudie Lemercier, Véronique Della-Valle, Francine Mugneret, Serge Romana, Michel Lessard, Isabelle Radford-Weiss, Marina Lafage-Pochitaloff, Olivier Bernard

Publikováno v: Blood
Blood, American Society of Hematology, 2006, 108 (13), pp.4198-201. 〈10.1182/blood-2006-07-032953〉
Blood, 2006, 108 (13), pp.4198-201. ⟨10.1182/blood-2006-07-032953⟩
Blood, American Society of Hematology, 2006, 108 (13), pp.4198-201. ⟨10.1182/blood-2006-07-032953⟩

International audience; The t(5;14)(q35;q32) chromosomal translocation is specifically observed in up to 20% of childhood T-cell acute lymphoblastic leukemia (T-ALL). It affects the BCL11B/CTIP2 locus on chromosome 14 and the RANBP17-TLX3/HOX11L2 reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6adf14ef0ddfbe9642775c149090b90
https://doi.org/10.1182/blood-2006-07-032953

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