Zobrazeno 1 - 10
of 53
pro vyhledávání: '"MESH : Insulin-Like Growth Factor I"'
Autor:
Noëlle Remoué, Juliana C. Lago, Romain Debret, Jennifer Molinari, Carine Mainzer, Patricia Rousselle, Dominique Sigaudo-Roussel, Carla Barricchello, Pascal Sommer
Publikováno v:
Experimental Dermatology
Experimental Dermatology, Wiley, 2018, 27 (5), pp.537-543. ⟨10.1111/exd.13547⟩
Experimental Dermatology, Wiley, 2018, 27 (5), pp.537-543. ⟨10.1111/exd.13547⟩
International audience; Ageing is a complex multifaceted process affecting skin functionality and structure. Several 3D organotypic skin culture models have reproduced ageing by inducing replicative senescence, glycation or oxidative stress. Yet, ver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996ab4d92699ba4207d91cc15d0ccf11
https://pubmed.ncbi.nlm.nih.gov/29603432
https://pubmed.ncbi.nlm.nih.gov/29603432
Autor:
Christian Brambilla, Patrick Auberger, Marie-Christine Favrot, Jean-Luc Coll, Amandine Hurbin, Laurence Dubrez-Daloz, Bernard Mari
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2005, 280 (20), pp.19757-67. 〈10.1074/jbc.M413516200〉
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2005, 280 (20), pp.19757-67. ⟨10.1074/jbc.M413516200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2005, 280 (20), pp.19757-67. 〈10.1074/jbc.M413516200〉
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2005, 280 (20), pp.19757-67. ⟨10.1074/jbc.M413516200⟩
International audience; Amphiregulin (AR) and insulin-like growth factor-1 (IGF1) are growth factors known to promote non-small cell lung cancer (NSCLC) survival. We have previously published that 1) AR and IGF1, secreted by H358 NSCLC cells, coopera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24c2c294a6eb4bbf90991a764bd80f2
https://doi.org/10.1074/jbc.m413516200
https://doi.org/10.1074/jbc.m413516200
Autor:
Luana Toniolo, L. Barberi, Astrid Y. Bijlsma, Antonio L. Serrano, Carel G. M. Meskers, Lars Larsson, Mario Pende, Rosario Rizzuto, Marco Sandri, Kenneth A. Dyar, Cristina Mammucari, Andrea B. Maier, Giorgia Pallafacchina, M. Roceri, Pura Muñoz-Cánoves, Stefano Schiaffino, Antonio Paoli, D. Pion, Giulia Milan, Bert Blaauw, Antonio Musarò, Carlo Reggiani, Vanina Romanello
Publikováno v:
Biogerontology, 14(3), 303-23. Springer Netherlands
Biogerontology
Biogerontology, Springer Verlag, 2013, 14 (3), pp.303-23. ⟨10.1007/s10522-013-9432-9⟩
Biogerontology; Vol 14
Sandri, M, Barberi, L, Bijlsma, A Y, Blaauw, B, Dyar, K A, Milan, G, Mammucari, C, Meskers, C G M, Pallafacchina, G, Paoli, A, Pion, D, Roceri, M, Romanello, V, Serrano, A L, Toniolo, L, Larsson, L, Maier, A B, Munoz-Canoves, P, Musaro, A, Pende, M, Reggiani, C, Rizzuto, R & Schiaffino, S 2013, ' Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway ', Biogerontology, vol. 14, no. 3, pp. 303-323 . https://doi.org/10.1007/s10522-013-9432-9
Biogerontology, 2013, 14 (3), pp.303-23. ⟨10.1007/s10522-013-9432-9⟩
Biogerontology, 14(3), 303-323. Springer Netherlands
Biogerontology, 14(3), 303-323
Sandri, M, Barberi, L, Bijlsma, A Y, Blaauw, B, Dyar, K A, Milan, G, Mammucari, C, Meskers, C G M, Pallafacchina, G, Paoli, A, Pion, D, Roceri, M, Romanello, V, Serrano, A L, Toniolo, L, Larsson, L, Maier, A B, Muñoz-Cánoves, P, Musarò, A, Pende, M, Reggiani, C, Rizzuto, R & Schiaffino, S 2013, ' Signalling pathways regulating muscle mass in ageing skeletal muscle : the role of the IGF1-Akt-mTOR-FoxO pathway ', Biogerontology, vol. 14, no. 3, pp. 303-23 . https://doi.org/10.1007/s10522-013-9432-9
Biogerontology
Biogerontology, Springer Verlag, 2013, 14 (3), pp.303-23. ⟨10.1007/s10522-013-9432-9⟩
Biogerontology; Vol 14
Sandri, M, Barberi, L, Bijlsma, A Y, Blaauw, B, Dyar, K A, Milan, G, Mammucari, C, Meskers, C G M, Pallafacchina, G, Paoli, A, Pion, D, Roceri, M, Romanello, V, Serrano, A L, Toniolo, L, Larsson, L, Maier, A B, Munoz-Canoves, P, Musaro, A, Pende, M, Reggiani, C, Rizzuto, R & Schiaffino, S 2013, ' Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway ', Biogerontology, vol. 14, no. 3, pp. 303-323 . https://doi.org/10.1007/s10522-013-9432-9
Biogerontology, 2013, 14 (3), pp.303-23. ⟨10.1007/s10522-013-9432-9⟩
Biogerontology, 14(3), 303-323. Springer Netherlands
Biogerontology, 14(3), 303-323
Sandri, M, Barberi, L, Bijlsma, A Y, Blaauw, B, Dyar, K A, Milan, G, Mammucari, C, Meskers, C G M, Pallafacchina, G, Paoli, A, Pion, D, Roceri, M, Romanello, V, Serrano, A L, Toniolo, L, Larsson, L, Maier, A B, Muñoz-Cánoves, P, Musarò, A, Pende, M, Reggiani, C, Rizzuto, R & Schiaffino, S 2013, ' Signalling pathways regulating muscle mass in ageing skeletal muscle : the role of the IGF1-Akt-mTOR-FoxO pathway ', Biogerontology, vol. 14, no. 3, pp. 303-23 . https://doi.org/10.1007/s10522-013-9432-9
International audience; During ageing skeletal muscles undergo a process of structural and functional remodelling that leads to sarcopenia, a syndrome characterized by loss of muscle mass and force and a major cause of physical frailty. To determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f4a5d65f36ee74ba4de2ecd531c858
https://hdl.handle.net/1871.1/c3edf814-3c90-4667-8713-c3a120aff07a
https://hdl.handle.net/1871.1/c3edf814-3c90-4667-8713-c3a120aff07a
Autor:
Mireille Dardenne, Wilson Savino
Publikováno v:
Current Opinion in Pharmacology
Current Opinion in Pharmacology, Elsevier, 2010, 10, pp.434-442. ⟨10.1016/j.coph.2010.04.002⟩
Current Opinion in Pharmacology, Elsevier, 2010, 10, pp.434-442. ⟨10.1016/j.coph.2010.04.002⟩
International audience; In the context of the cross-talk between the neuroendocrine and immune systems, it is well known that growth hormone (GH) exerts physiological effects in central as well as peripheral compartments of the immune system. GH modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6447974134648c1232f2030838f02a3d
https://doi.org/10.1016/j.coph.2010.04.002
https://doi.org/10.1016/j.coph.2010.04.002
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2009, 106 (24), pp.9902-7. ⟨10.1073/pnas.0811321106⟩
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (24), pp.9902-7. ⟨10.1073/pnas.0811321106⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2009, 106 (24), pp.9902-7. ⟨10.1073/pnas.0811321106⟩
Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (24), pp.9902-7. ⟨10.1073/pnas.0811321106⟩
Mammalian target of rapamycin (mTOR), a highly conserved protein kinase that controls cell growth and metabolism in response to nutrients and growth factors, is found in 2 structurally and functionally distinct multiprotein complexes termed mTOR comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73dfaafc5957185d67228b0e9199f474
https://doi.org/10.1073/pnas.0811321106
https://doi.org/10.1073/pnas.0811321106
Autor:
Teumer, Alexander, Qi, Qibin, Nethander, Maria, Aschard, Hugues, Bandinelli, Stefania, Beekman, Marian, Berndt, Sonja, Bidlingmaier, Martin, Broer, Linda, Cappola, Anne, Ceda, Gian Paolo, Chanock, Stephen, Chen, Ming-Huei, Chen, Tai, Chen, Yii-Der Ida, Chung, Jonathan, Del Greco Miglianico, Fabiola, Eriksson, Joel, Ferrucci, Luigi, Friedrich, Nele, Gnewuch, Carsten, Goodarzi, Mark, Grarup, Niels, Guo, Tingwei, Hammer, Elke, Hayes, Richard, Hicks, Andrew, Hofman, Albert, Houwing-Duistermaat, Jeanine, Hu, Frank, Hunter, David, Husemoen, Lise, Isaacs, Aaron, Jacobs, Kevin, Janssen, Joop, Jansson, John-Olov, Jehmlich, Nico, Johnson, Simon, Juul, Anders, Karlsson, Magnus, Kilpelainen, Tuomas, Kovacs, Peter, Kraft, Peter, Li, Chao, Linneberg, Allan, Liu, Yongmei, Loos, Ruth, Lorentzon, Mattias, Lu, Yingchang, Maggio, Marcello, Magi, Reedik, Meigs, James, Mellström, Dan, Nauck, Matthias, Newman, Anne, Pollak, Michael, Pramstaller, Peter, Prokopenko, Inga, Psaty, Bruce, Reincke, Martin, Rimm, Eric, Rotter, Jerome, Saint Pierre, Aude, Schurmann, Claudia, Seshadri, Sudha, Sjögren, Klara, Slagboom, P Eline, Strickler, Howard, Stumvoll, Michael, Suh, Yousin, Sun, Qi, Zhang, Cuilin, Svensson, Johan, Tanaka, Toshiko, Tare, Archana, Tönjes, Anke, Uh, Hae-Won, Van Duijn, Cornelia, van Heemst, Diana, Vandenput, Liesbeth, Vasan, Ramachandran, Völker, Uwe, Willems, Sara, Ohlsson, Claes, Wallaschofski, Henri, Kaplan, Robert, Chen, Ming‐Huei, Chen, Yii‐Der Ida, Houwing‐Duistermaat, Jeanine, Jansson, John‐Olov, Slagboom, P. Eline, Uh, Hae‐Won, Heemst, Diana
Publikováno v:
Aging Cell
Aging Cell, 15(5), 811-824
Aging cell, vol 15, iss 5
Aging Cell, Wiley Open Access, 2016, 15 (5), pp.811-824. ⟨10.1111/acel.12490⟩
Aging Cell, 15(5), 811-824. Wiley-Blackwell
Aging Cell, 15(5), 811-824. Wiley-Blackwell Publishing Ltd
Aging Cell, 15(5), 811-824
Aging cell, vol 15, iss 5
Aging Cell, Wiley Open Access, 2016, 15 (5), pp.811-824. ⟨10.1111/acel.12490⟩
Aging Cell, 15(5), 811-824. Wiley-Blackwell
Aging Cell, 15(5), 811-824. Wiley-Blackwell Publishing Ltd
The growth hormone/insulin-like growth factor (IGF) axis can be manipulated in animal models to promote longevity, and IGF-related proteins including IGF-I and IGF-binding protein-3 (IGFBP-3) have also been implicated in risk of human diseases includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c71dde8374929bb179f43c80584539
Autor:
Marie-Lise Maddelein, Virginie Garcia, Dimitri Pchejetski, Leyre Brizuela, Marie-Bernadette Delisle, Marie-Françoise Altié, A. Gomez-Brouchet, Olivier Cuvillier
Publikováno v:
Molecular Pharmacology
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2007, 72 (2), pp.341-349. ⟨10.1124/mol.106.033738⟩
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2007, 72 (2), pp.341-349. ⟨10.1124/mol.106.033738⟩
International audience; We examined the role of sphingosine kinase-1 (SphK1), a critical regulator of the ceramide/sphingosine 1-phosphate (S1P) biostat, in the regulation of death and survival of SH-SY5Y neuroblastoma cells in response to amyloid be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c72271c782e53f1330cbd1c98a5136
https://doi.org/10.1124/mol.106.033738
https://doi.org/10.1124/mol.106.033738
Autor:
Thierry Raclot, Fabrice Bertile
Publikováno v:
Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2004, 1683 (1-3), pp.101-109. ⟨10.1016/j.bbalip.2004.05.001⟩
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2004, 1683 (1-3), pp.101-109. ⟨10.1016/j.bbalip.2004.05.001⟩
International audience; The present study examines whether and to what extent the profiles of adipose-derived factors are altered in epididymal and subcutaneous adipose tissues of long-term fasted/refed and of fasted rats treated by recombinant lepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc7223c7b925b59b2ab67534b65c4ea
https://doi.org/10.1016/j.bbalip.2004.05.001
https://doi.org/10.1016/j.bbalip.2004.05.001
Autor:
Aurélie Dutour, Sana Intidhar Labidi-Galy, Pierre Heudel, Pierre Meeus, Jean-Yves Blay, Maria Chelghoum, Isabelle Ray-Coquard, Philippe A. Cassier, Laurent Alberti
Publikováno v:
Expert Opinion on Pharmacotherapy
Expert Opinion on Pharmacotherapy, Taylor & Francis, 2011, 12 (16), pp.2479-91. ⟨10.1517/14656566.2011.604633⟩
Expert Opinion on Pharmacotherapy, Taylor & Francis, 2011, 12 (16), pp.2479-91. 〈10.1517/14656566.2011.604633〉
Expert Opinion on Pharmacotherapy, Taylor & Francis, 2011, 12 (16), pp.2479-91. ⟨10.1517/14656566.2011.604633⟩
Expert Opinion on Pharmacotherapy, Taylor & Francis, 2011, 12 (16), pp.2479-91. 〈10.1517/14656566.2011.604633〉
International audience; INTRODUCTION: Soft-tissue sarcomas (STS) represent a heterogeneous group of malignant tumors originating from connective tissues. Over recent years, this heterogeneity has led to a molecular breakdown of STS and subsequent use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61087d817ff564d7c6569a79b35b8b9d
https://hal.archives-ouvertes.fr/hal-00787990
https://hal.archives-ouvertes.fr/hal-00787990
Publikováno v:
Experimental Gerontology
Experimental Gerontology, Elsevier, 2011, 46 (9), pp.747-754. ⟨10.1016/j.exger.2011.05.007⟩
Exp Gerontol
Exp Gerontol, 2011, 46 (9), pp.747-754. 〈10.1016/j.exger.2011.05.007〉
Experimental Gerontology, 2011, 46 (9), pp.747-754. ⟨10.1016/j.exger.2011.05.007⟩
Experimental Gerontology, Elsevier, 2011, 46 (9), pp.747-754. ⟨10.1016/j.exger.2011.05.007⟩
Exp Gerontol
Exp Gerontol, 2011, 46 (9), pp.747-754. 〈10.1016/j.exger.2011.05.007〉
Experimental Gerontology, 2011, 46 (9), pp.747-754. ⟨10.1016/j.exger.2011.05.007⟩
International audience; Epidemiological evidence related to increased death from hyperthermia suggests higher frailty in the elderly when exposed to high ambient temperatures. Despite the recent awareness of such public health problems, integrative s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256925c03b804df9560c8a769cb66d71
https://pubmed.ncbi.nlm.nih.gov/21620941
https://pubmed.ncbi.nlm.nih.gov/21620941