Výsledky vyhledávání - "MESH : HIV-1/immunology"

SAMHD1 Limits HIV-1 Antigen Presentation by Monocyte-Derived Dendritic Cells

Autor: Arnaud Moris, Françoise Porrot, Julia G. Prado, Timothée Bruel, Sylvain Cardinaud, Diana Ayinde, Olivier Schwartz

Publikováno v: Journal of Virology
Journal of Virology, 2015, 89 (14), pp.6994-7006. ⟨10.1128/JVI.00069-15⟩
Journal of Virology, American Society for Microbiology, 2015, 89 (14), pp.6994-7006. ⟨10.1128/JVI.00069-15⟩

Monocyte-derived dendritic cells (MDDC) stimulate CD8 + cytotoxic T lymphocytes (CTL) by presenting endogenous and exogenous viral peptides via major histocompatibility complex class I (MHC-I) molecules. MDDC are poorly susceptible to HIV-1, in part

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b482e90dd7b7429ef66a78fe4a510b57
https://doi.org/10.1128/jvi.00069-15

Zobrazit plný text záznamu

In Untreated HIV-1–Infected Children, PBMC-Associated HIV DNA Levels and Cell-Free HIV RNA Levels Are Correlated to Distinct T-lymphocyte Populations

Autor: Céline Didier, Christine Rouzioux, Stéphane Blanche, Marianne Burgard, Daniel Scott-Algara, Yves Rivière, Florence Buseyne

Publikováno v: Journal of Acquired Immune Deficiency Syndromes
Journal of Acquired Immune Deficiency Syndromes, Lippincott, Williams & Wilkins, 2010, 53 (5), pp.553-563. ⟨10.1097/QAI.0b013e3181cf060f⟩
Journal of Acquired Immune Deficiency Syndromes, 2010, 53 (5), pp.553-63. <10.1097/QAI.0b013e3181cf060f>
Journal of Acquired Immune Deficiency Syndromes, Lippincott, Williams & Wilkins, 2010, 53 (5), pp.553-563. 〈10.1097/QAI.0b013e3181cf060f〉
Journal of Acquired Immune Deficiency Syndromes-JAIDS
Journal of Acquired Immune Deficiency Syndromes-JAIDS, 2010, 53 (5), pp.553-563. ⟨10.1097/QAI.0b013e3181cf060f⟩

International audience; Background: Clinical studies support biologically independent roles of cell-free HIV particles and HIV-infected cells in disease progression. The associations between the level of infected cells and immune markers have been po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac44837a51de96786cecad033b47989
https://doi.org/10.1097/qai.0b013e3181cf060f

Zobrazit plný text záznamu

High proportion of PD-1-expressing CD4 + T cells in adipose tissue constitutes an immunomodulatory microenvironment that may support HIV persistence

Autor: Guillaume Pourcher, Abderaouf Damouche, Benoit Favier, Jean Jacques Lataillade, Bruno Vaslin, Valérie Pourcher, Christine Bourgeois, Elodie Busson, Olivier Lambotte, Mélanie Le Van, Stéphane Benoist, Thierry Lazure, Julien Adam, Michaela Müller-Trutwin

Publikováno v: European Journal of Immunology
European Journal of Immunology, 2017, 47 (12), pp.2113-2123. ⟨10.1002/eji.201747060⟩
European Journal of Immunology, Wiley-VCH Verlag, 2017, 47 (12), pp.2113-2123. ⟨10.1002/eji.201747060⟩

We and others have demonstrated that adipose tissue is a reservoir for HIV. Evaluation of the mechanisms responsible for viral persistence may lead to ways of reducing these reservoirs. Here, we evaluated the immune characteristics of adipose tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfca3eda57bdcf8b871126b640f92b28
https://doi.org/10.1002/eji.201747060

Zobrazit plný text záznamu

HIV-associated chronic immune activation

Autor: Michaela Müller-Trutwin, Mirko Paiardini

Publikováno v: Immunological Reviews
Immunological Reviews, 2013, 254 (1), pp.78-101. ⟨10.1111/imr.12079⟩
Immunological Reviews, Wiley, 2013, 254 (1), pp.78-101. ⟨10.1111/imr.12079⟩

International audience; Systemic chronic immune activation is considered today as the driving force of CD4(+) T-cell depletion and acquired immunodeficiency syndrome (AIDS). A residual chronic immune activation persists even in HIV-infected patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b122110966584d985efebb95a3e8aab
https://pubmed.ncbi.nlm.nih.gov/23772616

Zobrazit plný text záznamu

Immune responses against a new HIV-1 p24-gp41/pCAGGS-IL-12 DNA vaccine in Balb/c mice

Autor: Roodbari, Fatemeh, Sabahi, Farzaneh, Sarbolouki, Mohamad Nabi, Barkhordari, Farzaneh, Adeli, Ahmad, Jamedar, Amel, Mahboudi, Fereidoun

Publikováno v: Iranian Journal of Immunology
Iranian Journal of Immunology, Shiraz Institute for Cancer Research, 2012, 9 (2), pp.86-97

International audience; Background: Development of an effective vaccine is highly needed in order to restrict the AIDS pandemic. DNA vaccines initiate both arms of immunity without the potential of causing disease. HIV-1 p24 and gp41 (gag and env) pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3e1dbedd0fef6dbac541e88bc058c47e
https://pubmed.ncbi.nlm.nih.gov/22735796

Zobrazit plný text záznamu

Innate immunity in the control of HIV/AIDS

Autor: Ploquin, Mickaël J.-Y., Jacquelin, Béatrice, Jochems, Simon, Barré-Sinoussi, Françoise, Müller-Trutwin, Michaela

Publikováno v: AIDS
AIDS, Lippincott, Williams & Wilkins, 2012, 26 (10), pp.1269-1279. ⟨10.1097/QAD.0b013e328353e46b⟩
AIDS. Official journal of the international AIDS Society
AIDS. Official journal of the international AIDS Society, 2012, 26 (10), pp.1269-1279. ⟨10.1097/QAD.0b013e328353e46b⟩

International audience; From the publication of the first AIDS issue onwards, major advances have been made in the field of innate immunity during HIV infection. Innate immunity can be defined as the first and unspecific lines of defense constitutive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::939926d5c121b1b061837f738a2a6278
https://hal-pasteur.archives-ouvertes.fr/pasteur-02017960

Zobrazit plný text záznamu

Level of double negative T cells, which produce TGF-β and IL-10, predicts CD8 T-cell activation in primary HIV-1 infection

Autor: Laurence Weiss, Michaela Müller-Trutwin, Maria Elena Manea, Céline Didier, Gaël Petitjean, Anne-Sophie Liovat, Daniel Scott-Algara, Feriel Tibaoui, Pierre-Marie Girard, Laurence Meyer, Françoise Barré-Sinoussi, Mathieu F. Chevalier, Pauline Campa

Publikováno v: AIDS. Official journal of the international AIDS Society
AIDS. Official journal of the international AIDS Society, 2012, 26 (2), pp.139-148. ⟨10.1097/QAD.0b013e32834e1484⟩
AIDS
AIDS, Lippincott, Williams & Wilkins, 2012, 26 (2), pp.139-148. ⟨10.1097/QAD.0b013e32834e1484⟩

International audience; OBJECTIVE:Persistent immune activation plays a central role in the pathogenesis of HIV disease. Besides natural regulatory T cells (nTregs), 'double negative' T cells shown to exhibit regulatory properties could be involved in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62abd70daaa7192afcadea4ac47bdfed
https://hal-pasteur.archives-ouvertes.fr/pasteur-02006421

Zobrazit plný text záznamu

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

Autor: Christian Reinhard, Federico Santoni, Stéphane Hausmann, Matthew J Albert, Jessica Guerra, Aurélie Bisiaux, Caterina Strambio-De-Castillia, Thomas Pertel, Massimo Pizzato, Walther Mothes, Pradeep D. Uchil, Jeremy Luban, Josefina Lascano, Markus G. Grütter, Sara Züger, Laurence Chatel, Damien Morger

Publikováno v: Nature
Nature, Nature Publishing Group, 2011, 472 (7343), pp.361-5. ⟨10.1038/nature09976⟩
Nature, 2011, 472 (7343), pp.361-5. ⟨10.1038/nature09976⟩
Nature, Vol. 472, No 7343 (2011) pp. 361-365
Nature, vol. 472, no. 7343, pp. 361-5

International audience; TRIM5 is a RING domain-E3 ubiquitin ligase that restricts infection by human immunodeficiency virus (HIV)-1 and other retroviruses immediately following virus invasion of the target cell cytoplasm. Antiviral potency correlates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f87a4daed9097a6a6339041a9f7eb9
https://hal-pasteur.archives-ouvertes.fr/pasteur-01402086

Zobrazit plný text záznamu

Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity

Autor: Victor Appay, Jorge R. Almeida, Brigitte Autran, Daniel C. Douek, Gianfranco Pancino, Arnaud Moris, David Price, So Youn Shin, Martin Larsen, Delphine Sauce, Asier Sáez-Cirión, Laura Papagno

Publikováno v: Blood
Blood, American Society of Hematology, 2009, 113 (25), pp.6351-6360. ⟨10.1182/blood-2009-02-206557⟩
ResearcherID
Blood, 2009, 113 (25), pp.6351-6360. ⟨10.1182/blood-2009-02-206557⟩

CD8+ T cells are major players in the immune response against HIV. However, recent failures in the development of T cell–based vaccines against HIV-1 have emphasized the need to reassess our basic knowledge of T cell–mediated efficacy. CD8+ T cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277ef4f5b7f8025dc25aa5552091b4ef
https://hal.archives-ouvertes.fr/hal-02455368

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání