Zobrazeno 1 - 10
of 230
pro vyhledávání: '"MESH : Genomics"'
Autor:
Antoine Claessens, Lindsay B. Stewart, Eleanor Drury, Ambroise D. Ahouidi, Alfred Amambua-Ngwa, Mahamadou Diakite, Dominic P. Kwiatkowski, Gordon A. Awandare, David J. Conway
Publikováno v:
Microbial Genomics
Microbial Genomics, 2023, 9 (5), ⟨10.1099/mgen.0.001009⟩
Microbial Genomics, 2023, 9 (5), ⟨10.1099/mgen.0.001009⟩
Experimental studies on the biology of malaria parasites have mostly been based on laboratory-adapted lines, but there is limited understanding of how these may differ from parasites in natural infections. Loss-of-function mutants have previously bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d414b1778d4f013870ca250056decb17
https://doi.org/10.1099/mgen.0.001009
https://doi.org/10.1099/mgen.0.001009
Autor:
Karina T. Shirakawa, Fernanda Angélica Sala, Mayara M. Miyachiro, Viviana Job, Daniel Maragno Trindade, Andréa Dessen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (21), pp.e2219540120. ⟨10.1073/pnas.2219540120⟩
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (21), pp.e2219540120. ⟨10.1073/pnas.2219540120⟩
Peptidoglycan (PG) is a central component of the bacterial cell wall, and the disruption of its biosynthetic pathway has been a successful antibacterial strategy for decades. PG biosynthesis is initiated in the cytoplasm through sequential reactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1792c9045acdf80ae2e52e4fcc61ba
https://doi.org/10.1073/pnas.2219540120
https://doi.org/10.1073/pnas.2219540120
Autor:
Lamy-Besnier, Quentin, Bignaud, Amaury, Garneau, Julian, Titecat, Marie, Conti, Devon, von Strempel, Alexandra, Monot, Marc, Stecher, Bärbel, Koszul, Romain, Debarbieux, Laurent, Marbouty, Martial
Publikováno v:
Microbiome
Microbiome, 2023, 11 (1), pp.111. ⟨10.1186/s40168-023-01541-x⟩
Microbiome, 2023, 11 (1), pp.111. ⟨10.1186/s40168-023-01541-x⟩
Background Bacteria and their viruses, bacteriophages, are the most abundant entities of the gut microbiota, a complex community of microorganisms associated with human health and disease. In this ecosystem, the interactions between these two key com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21138f129d1db50fcf53c07514c0a100
https://hal-pasteur.archives-ouvertes.fr/pasteur-04158849/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-04158849/document
Autor:
Thi Oanh Bui, Van Tu Dao, Van Tai Nguyen, Jean-Paul Feugeas, Frédéric Pamoukdjian, Guilhem Bousquet
Publikováno v:
European Urology
European Urology, 2022, 81 (4), pp.349-361. ⟨10.1016/j.eururo.2021.12.010⟩
European Urology, 2022, 81 (4), pp.349-361. ⟨10.1016/j.eururo.2021.12.010⟩
International audience; Context: Although antiangiogenic treatments and immunotherapies have significantly improved the prognosis of metastatic renal cell carcinoma (RCC), many patients will develop resistance, leading to treatment failure. Genetic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6954158ec20fd4196a0ef261a1d75c22
https://doi.org/10.1016/j.eururo.2021.12.010
https://doi.org/10.1016/j.eururo.2021.12.010
Autor:
Clara Apicella, Camino S. M. Ruano, Basky Thilaganathan, Asma Khalil, Veronica Giorgione, Géraldine Gascoin, Louis Marcellin, Cassandra Gaspar, Sébastien Jacques, Colin E. Murdoch, Francisco Miralles, Céline Méhats, Daniel Vaiman
Publikováno v:
Cells
Cells, 2023, 12 (4), pp.578. ⟨10.3390/cells12040578⟩
Volume 12
Issue 4
Pages: 578
Cells, 2023, 12 (4), pp.578. ⟨10.3390/cells12040578⟩
Volume 12
Issue 4
Pages: 578
International audience; In this study, we attempted to find genetic variants affecting gene expression (eQTL = expression Quantitative Trait Loci) in the human placenta in normal and pathological situations. The analysis of gene expression in placent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e37124424e7f0a7f13060051584b876
https://u-paris.hal.science/hal-04096063
https://u-paris.hal.science/hal-04096063
Autor:
Mark Stoneking, Leonardo Arias, Dang Liu, Sandra Oliveira, Irina Pugach, Jae Joseph Russell B. Rodriguez
Publikováno v:
Stoneking, Mark; Arias, Leonardo; Liu, Dang; Oliveira, Sandra; Pugach, Irina; Rodriguez, Jae Joseph Russell B (2023). Genomic perspectives on human dispersals during the Holocene. Proceedings of the National Academy of Sciences of the United States of America-PNAS, 120(4), e2209475119. National Academy of Sciences NAS 10.1073/pnas.2209475119
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (4), ⟨10.1073/pnas.2209475119⟩
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (4), ⟨10.1073/pnas.2209475119⟩
International audience; Nearly 20 y ago, Jared Diamond and Peter Bellwood reviewed the evidence for the associated spread of farming and large language families by the demographic expansions of farmers. Since then, advances in obtaining and analyzing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c51e638b67bc61b2c7454f64298a19
Autor:
Francois Edidi-Atani, Moussa Moïse Diagne, Meris Matondo-Kuamfumu, Junior Bulabula, Kristian G. Andersen, Bibiche Nsunda, Eric Delaporte, Bailey White, Amadou A. Sall, Trevor Bedford, Matthias Pauthner, Martine Peeters, Nella Bisento, Jean Jacques Muyembe Tamfum, Marceline Akonga, James Hadfield, Daniel Mukadi, Michael R. Wiley, Gustavo Palacios, Fabrice Mambu-Mbika, Amuri Aziza, Nicholas Di Paola, Steve Ahuka-Mundeke, Eddy Kinganda-Lusamaki, Catherine Pratt, Ousmane Faye, Martin Faye, Allison Black, Placide Mbala-Kingebeni
Publikováno v:
Nat Med
Nature Medicine
Nature Medicine, 2021, 27 (4), pp.710-716. ⟨10.1038/s41591-021-01302-z⟩
Nature Medicine
Nature Medicine, 2021, 27 (4), pp.710-716. ⟨10.1038/s41591-021-01302-z⟩
On 1 August 2018, the Democratic Republic of the Congo (DRC) declared its tenth Ebola virus disease (EVD) outbreak. To aid the epidemiologic response, the Institut National de Recherche Biomedicale (INRB) implemented an end-to-end genomic surveillanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227ccff0ce444d0fb27dd297b6dc0920
https://doi.org/10.1038/s41591-021-01302-z
https://doi.org/10.1038/s41591-021-01302-z
Autor:
Hennart Melanie, Guglielmini Julien, Bridel Sébastien, Maiden Martin C.J., Jolley Keith A., Criscuolo Alexis, Brisse Sylvain
Publikováno v:
Molecular Biology and Evolution
Molecular Biology and Evolution, 2022, 39 (7), pp.msac135. ⟨10.1093/molbev/msac135⟩
Molecular Biology and Evolution, 2022, 39 (7), pp.msac135. ⟨10.1093/molbev/msac135⟩
Sublineages within microbial species can differ widely in their ecology and pathogenicity, and their precise definition is important in basic research and industrial or public health applications. Whereas the classification and naming of prokaryotes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ffece0de86e719f45d3bec66fe61bf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03759200/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03759200/document
Autor:
Sébastien Bridel, Valérie Bouchez, Bryan Brancotte, Sofia Hauck, Nathalie Armatys, Annie Landier, Estelle Mühle, Sophie Guillot, Julie Toubiana, Martin C. J. Maiden, Keith A. Jolley, Sylvain Brisse
Publikováno v:
Nature Communications
Nature Communications, 2022, 13 (1), pp.3807. ⟨10.1038/s41467-022-31517-8⟩
Nature Communications, 2022, 13 (1), pp.3807. ⟨10.1038/s41467-022-31517-8⟩
The genus Bordetella includes bacteria that are found in the environment and/or associated with humans and other animals. A few closely related species, including Bordetella pertussis, are human pathogens that cause diseases such as whooping cough. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90703a9e549eafff7139105317da0089
https://doi.org/10.1038/s41467-022-31517-8
https://doi.org/10.1038/s41467-022-31517-8
Publikováno v:
PLoS Biology
PLoS Biology, 2022, 20 (11), pp.e3001893. ⟨10.1371/journal.pbio.3001893⟩
PLoS Biology, 2022, 20 (11), pp.e3001893. ⟨10.1371/journal.pbio.3001893⟩
Diatoms form a diverse and abundant group of photosynthetic protists that are essential players in marine ecosystems. However, the microevolutionary structure of their populations remains poorly understood, particularly in polar regions. Exploring ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdee47156aba9ee1c649df880d6b2bc6
https://pubmed.ncbi.nlm.nih.gov/36441816
https://pubmed.ncbi.nlm.nih.gov/36441816