Zobrazeno 1 - 10
of 146
pro vyhledávání: '"MESH : Gene Expression Regulation, Enzymologic"'
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9226, p 9226 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (23), pp.9226. ⟨10.3390/ijms21239226⟩
International Journal of Molecular Sciences, 2020, 21 (23), pp.9226. ⟨10.3390/ijms21239226⟩
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (23), pp.9226. ⟨10.3390/ijms21239226⟩
International Journal of Molecular Sciences, 2020, 21 (23), pp.9226. ⟨10.3390/ijms21239226⟩
International audience; Cancer is the second leading cause of death with tens of millions of people diagnosed with cancer every year around the world. Most radio- and chemotherapies aim to eliminate cancer cells, notably by causing severe damage to t
Autor:
Camille Hallez, Cristina M. Dorobantu, Mohamed S Bouzidi, Valérie Thiers, Vincent Lucansky, Jean-Pierre Vartanian, Xiongxiong Li, Simon Wain-Hobson, Raphael Gaudin, Rodolphe Suspène
Publikováno v:
Nature Microbiology
Nature Microbiology, 2019, 4 (7), pp.1196-1207. ⟨10.1038/s41564-019-0405-x⟩
Nature Microbiology, Nature Publishing Group, 2019, 4 (7), pp.1196-1207. ⟨10.1038/s41564-019-0405-x⟩
Nature Microbiology, 2019, 4 (7), pp.1196-1207. ⟨10.1038/s41564-019-0405-x⟩
Nature Microbiology, Nature Publishing Group, 2019, 4 (7), pp.1196-1207. ⟨10.1038/s41564-019-0405-x⟩
International audience; Numerous human APOBEC3 cytidine deaminases have proven to be, inter alia, host cell restriction factors for retroviruses and hepadnaviruses. Although they can bind to genomic RNA and become encapsidated, they are only catalyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5b9df1192a8473ace5d62d1f522f99
https://hal-pasteur.archives-ouvertes.fr/pasteur-02424852
https://hal-pasteur.archives-ouvertes.fr/pasteur-02424852
Publikováno v:
International Journal of Developmental Biology
International Journal of Developmental Biology, University of the Basque Country Press, 2017, 61 (10-11-12), pp.733-747. ⟨10.1387/ijdb.170227ms⟩
International Journal of Developmental Biology, University of the Basque Country Press, 2017, 61 (10-11-12), pp.733-747. ⟨10.1387/ijdb.170227ms⟩
International audience; During development, morphogens, such as retinoic acid (RA), act as mediators of intercellular communication systems to control patterning and cell fate specification processes. In vertebrates, the tightly regulated production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a10f8f7db29d0e2a1a58a5ebe43967
https://hal.archives-ouvertes.fr/hal-02110617/document
https://hal.archives-ouvertes.fr/hal-02110617/document
Autor:
Claude Didierjean, Nicolas Rouhier, Thomas Roret, José M. Gualberto, Jean-Michel Girardet, Pascale Tsan, Pierre-Alexandre Lallement, Arnaud Hecker
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2016, 473 (6), pp.717-31. ⟨10.1042/BJ20151147⟩
Biochemical Journal, Portland Press, 2016, 473 (6), pp.717-31. ⟨10.1042/BJ20151147⟩
International audience; Dehydroascorbate reductases (DHARs), enzymes belonging to the GST superfamily, catalyse the GSH-dependent reduction of dehydroascorbate into ascorbate in plants. By maintaining a reduced ascorbate pool, they notably participat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bcb27224f7a75f8c6ede857d239411
https://hal.archives-ouvertes.fr/hal-01287772
https://hal.archives-ouvertes.fr/hal-01287772
Autor:
Cedric Moro, Steven R. Smith, Camille Loubière, Aline Mairal, Dominique Langin, Virginie Bourlier, Pierre-Marie Badin, Katie Louche, Arild C. Rustan, Geneviève Tavernier, Maarten Coonen
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 839-848 (2012)
Journal of Lipid Research
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2012, 53 (5), pp.839-48. ⟨10.1194/jlr.M019182⟩
Journal of Lipid Research, 2012, 53 (5), pp.839-48. ⟨10.1194/jlr.M019182⟩
Journal of Lipid Research
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2012, 53 (5), pp.839-48. ⟨10.1194/jlr.M019182⟩
Journal of Lipid Research, 2012, 53 (5), pp.839-48. ⟨10.1194/jlr.M019182⟩
International audience; We investigated here the specific role of CGI-58 in the regulation of energy metabolism in skeletal muscle. We first examined CGI-58 protein expression in various muscle types in mice, and next modulated CGI-58 expression duri
Autor:
Xavier Montagutelli, Marie-Pascale Frenkiel, Jean-Louis Guénet, Dominique Simon-Chazottes, Philippe Desprès, Jean-Jacques Panthier
Publikováno v:
Virology
Virology, Elsevier, 2011, 417 (1), pp.147-53. ⟨10.1016/j.virol.2011.05.018⟩
Virology, 2011, 417 (1), pp.147-53. ⟨10.1016/j.virol.2011.05.018⟩
Virology, Elsevier, 2011, 417 (1), pp.147-53. ⟨10.1016/j.virol.2011.05.018⟩
Virology, 2011, 417 (1), pp.147-53. ⟨10.1016/j.virol.2011.05.018⟩
International audience; Susceptibility of inbred strains to infection with West Nile virus (WNV) has been genetically associated with an arginine-to-a nonsense codon substitution at position 253 (R253X) in the predicted sequence of the murine 2',5'-o
Autor:
Emmanuelle Liaudet-Coopman, Anne-Sophie Bach, Christine Prébois, Valérie Laurent-Matha, Danielle Derocq, Sophie Pattingre, Olivier Masson
Publikováno v:
Biochimie
Biochimie, Elsevier, 2010, 92 (11), pp.1635-43. ⟨10.1016/j.biochi.2010.05.009⟩
Biochimie, Elsevier, 2010, 92 (11), pp.1635-43. ⟨10.1016/j.biochi.2010.05.009⟩
International audience; The lysosomal aspartic protease cathepsin D (cath-D) is overexpressed and hyper-secreted by epithelial breast cancer cells. This protease is an independent marker of poor prognosis in breast cancer as it is correlated with the
Autor:
Corinne Quittau-Prévostel, Vincent Cavaillès, Robert I. Glazer, Philippe Jay, Rana Abdel-Samad, Dominique Joubert, Sébastien Dupasquier, Pauline Bastide, Philippe Blache
Publikováno v:
Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2009, 122 (13), pp.2191-2196. ⟨10.1242/jcs.036483⟩
Journal of Cell Science, Company of Biologists, 2009, 122 (13), pp.2191-2196. ⟨10.1242/jcs.036483⟩
International audience; Variations of protein kinase C (PKC) expression greatly influence the proliferation-to-differentiation transition (PDT) of intestinal epithelial cells and might have an important impact on intestinal tumorigenesis. We demonstr
Autor:
Nathalie Pizzinat, Mansour Akkiki, Angelo Parini, Marie-Hélène Seguelas, Samiye Yabanoglu, Jeanne Mialet-Perez
Publikováno v:
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, 2009, 46 (4), pp.518-25. ⟨10.1016/j.yjmcc.2008.12.019⟩
Journal of Molecular and Cellular Cardiology, 2009, 46 (4), pp.518-25. ⟨10.1016/j.yjmcc.2008.12.019⟩
Platelet activation occurs in different acute and chronic heart diseases including myocardial infarction, obstructive hypertrophic cardiomyopathy and valve stenosis. Recent studies suggested that some factors secreted by activated platelets may parti
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2008, 28 (1), pp.511-27. ⟨10.1128/MCB.00800-07⟩
Molecular and Cellular Biology, American Society for Microbiology, 2008, 28 (1), pp.511-27. ⟨10.1128/MCB.00800-07⟩
The proteins ERK1 and ERK2 are highly similar, are ubiquitously expressed, and share activators and substrates; however, erk2 gene invalidation is lethal in mice, while erk1 inactivation is not. We ablated ERK1 and/or ERK2 by RNA interference and exp