Identification of a functional FADS1 3′UTR variant associated with erythrocyte n-6 polyunsaturated fatty acids levels

Autor: Xavier Hermant, Amandine Flaig, Dominique Cottel, Gilbert Briand, Brigitte Laillet, Chantal Simon, Aline Meirhaeghe, Marie-Adélaïde Bout, Julie Dumont, Dominique Arveiler, Aline Wagner, Jean Dallongeville, Charlotte Delay, Jean-Bernard Ruidavets, Jimena Luque-Bedregal, Jean Ferrières, Philippe Amouyel

Publikováno v: Journal of clinical lipidology
Journal of clinical lipidology, Elsevier, 2018, 12 (5), pp.1280--1289. ⟨10.1016/j.jacl.2018.07.012⟩
Journal of clinical lipidology, 2018, 12 (5), pp.1280--1289. ⟨10.1016/j.jacl.2018.07.012⟩

International audience; BACKGROUND: Blood polyunsaturated fatty acid (PUFA) levels are determined by diet and by endogenous synthesis via Delta 5- and Delta 6-desaturases (encoded by the FADS] and FADS2 genes, respectively). Genome-wide association s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776b9882168384015577c4c64face99e
https://doi.org/10.1016/j.jacl.2018.07.012

Expression of a desaturase gene, desat1, in neural and nonneural tissues separately affects perception and emission of sex pheromones in Drosophila

Autor: François Bousquet, Tetsuya Nojima, Daisuke Yamamoto, Isabelle Chauvel, Jean François Ferveur, Benjamin Houot, Stéphane Dupas, Sylvie Chaudy

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (1), pp.249-54. ⟨10.1073/pnas.1109166108⟩
Proceedings-National Academy of Sciences Usa
Proceedings-National Academy of Sciences Usa, 2012, 109 (1), pp.249-54. 〈10.1073/pnas.1109166108〉

Animals often use sex pheromones for mate choice and reproduction. As for other signals, the genetic control of the emission and perception of sex pheromones must be tightly coadapted, and yet we still have no worked-out example of how these two aspe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00156b2f8c476228f4b5012020e3901
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-00723157

Hydroxyacyl-CoA dehydrase and trans-2,3-enoyl-CoA reductase activities are consistent with long-chain fatty acid accumulation during rat brain development

Autor: Anja Knoll, Françoise Sargueil, Claude Cassagne, Bertrand Garbay, Jérôme Salles, Karine Lucet-Levannier

Publikováno v: Neuroscience Letters
Neuroscience Letters, 1999, 263 (1), pp.5-8. ⟨10.1016/s0304-3940(99)00094-4⟩

International audience; The developmental changes of microsomal 3-hydroxyacyl-CoA dehydrase and trans-2,3-enoyl-CoA reductase activities were analyzed and compared to very-long-chain fatty acid content and biosynthesis in rat brain. Contrary to the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b5054ba8ad440251624e2f8aa8b236
https://doi.org/10.1016/s0304-3940(99)00094-4

The fatty acid desaturase 3 gene encodes for different FADS3 protein isoforms in mammalian tissues

Autor: Philippe Legrand, H. Blanchard, Frédérique Pédrono, Maela Kloareg, Stéphanie Daval, Sabine d'Andrea, Vincent Rioux

Publikováno v: Journal of Lipid Research
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2010, 51 (3), pp.472-9. ⟨10.1194/jlr.M000588⟩
Journal of Lipid Research (51), 472-479. (2010)
Journal of Lipid Research, Vol 51, Iss 3, Pp 472-479 (2010)

In 2000, Marquardt et al. (A. Marquardt, H. Stöhr, K. White, and B. H. F. Weber. 2000. cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family. Genomics. 66: 176-183.) described the ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc305542ce8d7f59d6c8ecbfce73ca79
https://hal-agrocampus-ouest.archives-ouvertes.fr/hal-00729632

New regulatory and signal functions for myristic acid

Autor: Erwan, Beauchamp, Vincent, Rioux, Philippe, Legrand

Publikováno v: médecine/sciences
médecine/sciences, EDP Sciences, 2009, 25 (1), pp.57-63. ⟨10.1051/medsci/200925157⟩

Myristic acid is a 14 carbon saturated fatty acid, which is mostly found in milk fat. In industrialized countries, its excessive consumption is correlated with an increase in plasma cholesterol and mortality due to cardiovascular diseases. Neverthele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c4d3ebea67405052baa012780c7caa84
https://hal-agrocampus-ouest.archives-ouvertes.fr/hal-00730028