The pore structure of Clostridium perfringens epsilon toxin

Autor: Savva, Christos, Clark, Alice, Naylor, Claire, Popoff, Michel, Moss, David, Basak, Ajit, Titball, Richard, Bokori-Brown, Monika

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.2641. ⟨10.1038/s41467-019-10645-8⟩
Nature Communications, 2019, 10 (1), pp.2641. ⟨10.1038/s41467-019-10645-8⟩

Epsilon toxin (Etx), a potent pore forming toxin (PFT) produced by Clostridium perfringens, is responsible for the pathogenesis of enterotoxaemia of ruminants and has been suggested to play a role in multiple sclerosis in humans. Etx is a member of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::03b5647c6160a8077e0ad0ee01cd113c
https://hal-pasteur.archives-ouvertes.fr/pasteur-02454060

Correlation between in vitro cytotoxicity and in vivo lethal activity in mice of epsilon toxin mutants from Clostridium perfringens

Autor: Dorca Arévalo, Jonatan, Pauillac, Serge, Díaz Hidalgo, Laura, Martín Satué, Mireia, Popoff, Michel R., Blasi Cabús, Joan

Publikováno v: PLoS ONE, Vol 9, Iss 7, p e102417 (2014)
PLoS ONE
PLoS ONE, Public Library of Science, 2014, 9 (7), pp.e102417. 〈10.1371/journal.pone.0102417〉
PLoS ONE, Public Library of Science, 2014, 9 (7), pp.e102417. ⟨10.1371/journal.pone.0102417⟩
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE, 2014, 9 (7), pp.e102417. ⟨10.1371/journal.pone.0102417⟩
Recercat. Dipósit de la Recerca de Catalunya
instname

International audience; Epsilon toxin (Etx) from Clostridium perfringens is a pore-forming protein with a lethal effect on livestock, producing severe enterotoxemia characterized by general edema and neurological alterations. Site-specific mutations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c25f0ed7b0170d4b6bc580ecf3b721f4
http://europepmc.org/articles/PMC4094505?pdf=render