Výsledky vyhledávání - "MESH : Drug Carriers"

Nanoparticle heterogeneity: an emerging structural parameter influencing particle fate in biological media?

Autor: Soudeh F. Tehrani, Patrice Hildgen, Vahid Adibnia, Xavier Banquy, Steven Sanche, Jean-Michel Rabanel, Charles Ramassamy

Publikováno v: Nanoscale
Nanoscale, Royal Society of Chemistry, 2019, 11 (2), pp.383-406. ⟨10.1039/c8nr04916e⟩

International audience; Drug nanocarriers' surface chemistry is often presumed to be uniform. For instance, the polymer surface coverage and distribution of ligands on nanoparticles are described with averaged values obtained from quantification tech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c497e68b27e54f7695131323152d44d6
https://doi.org/10.1039/c8nr04916e

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PEGylated Protamine Letrozole Nanoparticles: A Promising Strategy to Combat Human Breast Cancer via MCF-7 Cell Lines

Autor: Muhammad Tafhim Khan, Zia Uddin, Muhammad Arslan Javed, Nabi Shah, Hamid Bashir, Ahson Jabbar Shaikh, Muhammad Shahid Riaz Rajoka, Muhammad Imran Amirzada, Muhammad Hassham Hassan Bin Asad

Publikováno v: BioMed Research International
BioMed Research International, 2022, 2022, pp.1-7. ⟨10.1155/2022/4438518⟩

The objective of the study was to develop PEGylated protamine letrozole nanoparticles to combat human breast cancer by modifying the release pattern of letrozole. Breast cancer is amongst the most prevalent diseases in women due to overactivity of hu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dfeadd4db8c17c70e22f5a8e800708

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Sustained-release microparticle dry powders of chloramphenicol palmitate or thiamphenicol palmitate prodrugs for lung delivery as aerosols

Autor: Siti Nani Nurbaeti, Julien Brillault, Frederic Tewes, Jean-Christophe Olivier

Publikováno v: European Journal of Pharmaceutical Sciences
European Journal of Pharmaceutical Sciences, Elsevier, 2019, 138, pp.105028. ⟨10.1016/j.ejps.2019.105028⟩

International audience; The purpose of this study was to design inhalable sustained-release nanoparticle-in-microparticles, i.e. nano-embedded microparticles, for the lung delivery of chloramphenicol or thiamphenicol as aerosols. The palmitate ester

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac1edbc87ddf480294123470513c38d
https://hal.archives-ouvertes.fr/hal-02477590

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Poly ethylene glycol (PEG)-Related controllable and sustainable antidiabetic drug delivery systems

Autor: Ding Ying, Jiang Liu, Litao Zhang, Peng Yu, Yongmin Zhang, Yupeng Fu

Publikováno v: European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2021, 217, pp.113372. ⟨10.1016/j.ejmech.2021.113372⟩

International audience; Diabetes mellitus is one of the most challenging threats to global public health. To improve the therapy efficacy of antidiabetic drugs, numerous drug delivery systems have been developed. Polyethylene glycol (PEG) is a polyme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da57c36cad06f95021d621f7ea25bfd3
https://doi.org/10.1016/j.ejmech.2021.113372

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Updated Progress of Nanocarrier-Based Intranasal Drug Delivery Systems for Treatment of Brain Diseases

Autor: Min Chen, Ying Fan, Wen Wu, Xuefeng Xia, Philippe Maincent, Jinqiang Zhang

Publikováno v: Critical Reviews in Therapeutic Drug Carrier Systems
Critical Reviews in Therapeutic Drug Carrier Systems, Begell House, 2018, 35 (5), pp.433-467. ⟨10.1615/CritRevTherDrugCarrierSyst.2018024697⟩

International audience; Intranasal drug delivery is emerging as a reliable and promising pathway to deliver a wide range of therapeutic agents including small and large molecules, peptides and proteins, genes to the central nervous system for the tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a15fe2cd2b34a5e5bfeb121c7180190
https://pubmed.ncbi.nlm.nih.gov/30317945

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Targeted Shiga toxin–drug conjugates prepared via Cu-free click chemistry

Autor: Frédéric Schmidt, Siau-Kun Bai, Vesela Kostova, Estelle Dransart, Michel Azoulay, Ludger Johannes, Jean-Claude Florent, Laura Brulle

Publikováno v: Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2015, 23 (22), pp.7150-7. ⟨10.1016/j.bmc.2015.10.010⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2015, 23 (22), pp.7150-7157. ⟨10.1016/j.bmc.2015.10.010⟩

International audience; The main drawback of the anticancer chemotherapy consists in the lack of drug selectivity causing severe side effects. The targeted drug delivery appears to be a very promising strategy for controlling the biodistribution of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30dfa4fef304d17b163c1984ba7968ca
https://doi.org/10.1016/j.bmc.2015.10.010

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Self-aggregation of cationically modified poly( ε -caprolactone) 2 - co -poly(ethylene glycol) copolymers: Effect of cationic grafting ligand and poly( ε -caprolactone) chain length

Autor: Varaporn Buraphacheep Junyaprasert, Pimchanok Charoongchit, Anne Sapin-Minet, Philippe Maincent, Kittisak Sripha, Shirui Mao, Jiraphong Suksiriworapong

Publikováno v: Materials Science and Engineering: C
Materials Science and Engineering: C, Elsevier, 2017, 72, pp.444-455. ⟨10.1016/j.msec.2016.11.043⟩

International audience; Cationic copolymers have been attractive to investigate due to their potential to complexation with anionic drugs and expected to use in the pharmaceutical application. In this study, the modified poly(ε-caprolactone)2-co-pol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177f9968ee92d0f7f6e1783ce1d40440
https://hal.univ-lorraine.fr/hal-02923638

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Recent advances in theranostic nanocarriers of doxorubicin based on iron oxide and gold nanoparticles

Autor: Martin Soucé, Juliette Gautier, Emilie Munnier, Igor Chourpa, Emilie Allard-Vannier

Publikováno v: Journal of Controlled Release
Journal of Controlled Release, Elsevier, 2013, 169 (1-2), pp.48-61. ⟨10.1016/j.jconrel.2013.03.018⟩

International audience; Hybrid (organic/inorganic) nanoparticles emerged as a simple solution to build "theranostic" systems. Due to their physical properties, superparamagnetic iron oxide nanoparticles (SPIONs) and plasmonic gold nanoparticles (Au-N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fbd30e26f8bdc707aaeb601ae97c8d
https://doi.org/10.1016/j.jconrel.2013.03.018

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Drug delivery by polymeric nanoparticles induces autophagy in macrophages

Autor: B. Mograbi, Juliana Tournebize, B. Foliguet, I. Aboukhamis, Philippe Maincent, Housam Eidi, Olivier Joubert, A. Le Faou, Bertrand H. Rihn, C. Némos, Stéphanie Grandemange

Publikováno v: International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2012, 422 (1-2), pp.495-503. ⟨10.1016/j.ijpharm.2011.11.020⟩

International audience; Drug delivery nanosystems are currently used in human therapy. In preliminary studies we have observed that Eudragit RS nanoparticles, prepared by nanoprecipitation or double emulsion techniques, are cytotoxic for NR8383 rat m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68751aafb292e44c4d56a780f74e2eda
https://doi.org/10.1016/j.ijpharm.2011.11.020

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Conjugation of doxorubicin to cell penetrating peptides sensitizes human breast MDA-MB 231 cancer cells to endogenous TRAIL-induced apoptosis

Autor: Jacqueline Bréard, Michel De Waard, Jocelyne Hamelin, Souhir Brahim, Abderraouf Kenani, Sonia Aroui

Publikováno v: Apoptosis
Apoptosis, Springer Verlag, 2009, 14 (11), pp.1352-65. ⟨10.1007/s10495-009-0397-8⟩
Apoptosis, 2009, 14 (11), pp.1352-65. ⟨10.1007/s10495-009-0397-8⟩

International audience; Previous work from our laboratory has shown that coupling doxorubicin (Dox) to cell penetrating peptides (Dox-CPPs) is a good strategy to overcome Dox resistance in MDA-MB 231 breast cancer cells. We also reported that, in con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc9b43dd0ddfd42c3b7ebb17e8da7a4
https://doi.org/10.1007/s10495-009-0397-8

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