Výsledky vyhledávání - "MESH : Disease Progression"

Hypoxia-mediated stabilization of HIF1A in prostatic intraepithelial neoplasia promotes cell plasticity and malignant progression

Autor: Mohamed A. Abu el Maaty, Julie Terzic, Céline Keime, Daniela Rovito, Régis Lutzing, Darya Yanushko, Maxime Parisotto, Elise Grelet, Izzie Jacques Namer, Véronique Lindner, Gilles Laverny, Daniel Metzger

Publikováno v: Science Advances
Science Advances, 2022, 8 (29), pp.eabo2295. ⟨10.1126/sciadv.abo2295⟩

Prostate cancer (PCa) is a leading cause of cancer-related deaths. The slow evolution of precancerous lesions to malignant tumors provides a broad time frame for preventing PCa. To characterize prostatic intraepithelial neoplasia (PIN) progression, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a12503256470fa371e90421e043176
https://hal.science/hal-03766697/file/MAM_2022_sciadv.abo2295.pdf

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Speech Biomarkers in Rapid Eye Movement Sleep Behavior Disorder and Parkinson Disease

Publikováno v: Annals of Neurology
Annals of Neurology, 2021, 90 (1), pp.62-75. ⟨10.1002/ana.26085⟩

International audience; Objective: This multilanguage study used simple speech recording and high-end pattern analysis to provide sensitive and reliable noninvasive biomarkers of prodromal versus manifest α-synucleinopathy in patients with idiopathi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4e0d32ec9c857edcd1a73d567a0dd8
http://europepmc.org/articles/PMC8252762

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Five‐Year Lower Extremity Function is Associated with White Matter Abnormality in Older Adults

Autor: Bruno Vellas, Jean-François Mangin, Philipe de Souto Barreto, Kelly Virecoulon Giudici, Audrey Gabelle, Lisa Perus, Yves Rolland, Lingxiao He

Publikováno v: Journal of the American Geriatrics Society
Journal of the American Geriatrics Society, 2021, 69 (4), pp.995-1002. ⟨10.1111/jgs.16989⟩

International audience; Objective: To explore associations between changes of lower extremity function (LEF) parameters over a 5-year period and diffusion tensor imaging (DTI) parameters of white matter tracts among community-dwelling older adults.De

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f67528b31f034da42e1f4a086a40ec
https://doi.org/10.1111/jgs.16989

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Natural history of Type 2 and 3 spinal muscular atrophy: 2‐year NatHis‐SMA study

Publikováno v: Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology, 2021, 8 (2), pp.359-373. ⟨10.1002/acn3.51281⟩
Annals of Clinical and Translational Neurology, Vol 8, Iss 2, Pp 359-373 (2021)
Annals of Clinical and Translational Neurology, Wiley, 2021, 8 (2), pp.359-373. ⟨10.1002/acn3.51281⟩

OBJECTIVE: To characterize the natural history of spinal muscular atrophy (SMA) over 24 months using innovative measures such as wearable devices, and to provide evidence for the sensitivity of these measures to determine their suitability as endpoin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05a8b9907c355ce4ae932b73230e98b
http://europepmc.org/articles/PMC7886049

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Environmental chemicals, breast cancer progression and drug resistance

Autor: Koual, Meriem, Tomkiewicz, Céline, Cano-Sancho, German, Antignac, Jean-Philippe, Bats, Anne-Sophie, Coumoul, Xavier

Publikováno v: Environmental Health, Vol 19, Iss 1, Pp 1-25 (2020)
Environmental Health
Environmental Health, BioMed Central, 2020, 19 (1), ⟨10.1186/s12940-020-00670-2⟩

Breast cancer (BC) is one of the most common causes of cancer in the world and the second leading cause of cancer deaths among women. Mortality is associated mainly with the development of metastases. Identification of the mechanisms involved in meta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4a3d1c91618f334d729e1a45bc387e44
http://link.springer.com/article/10.1186/s12940-020-00670-2

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Switch maintenance chemotherapy versus observation after carboplatin and weekly paclitaxel doublet chemotherapy in elderly patients with advanced non–small cell lung cancer: IFCT-1201 MODEL trial

Publikováno v: European Journal of Cancer
European Journal of Cancer, 2020, 138, pp.193-201. ⟨10.1016/j.ejca.2020.07.034⟩
European Journal of Cancer, Elsevier, 2020, 138, pp.193-201. ⟨10.1016/j.ejca.2020.07.034⟩

International audience; Purpose: Maintenance chemotherapy is a reasonable choice for patients with metastatic non-small cell lung carcinoma (NSCLC) not progressing after induction therapy with a platinum-based doublet. Nevertheless, there have been n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c034c6fffdebcc9111506c34b7f426b
https://doi.org/10.1016/j.ejca.2020.07.034

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Differential levels of Neurofilament Light protein in cerebrospinal fluid in patients with a wide range of neurodegenerative disorders

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
r-IIB SANT PAU: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut dInvestigació Biomèdica Sant Pau (IIB Sant Pau)
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.9161. ⟨10.1038/s41598-020-66090-x⟩
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Altres ajuts: "Marató TV3" grant (20141210, 044412, 20143710). Cerebrospinal fluid (CSF) biomarkers are useful in the diagnosis and the prediction of progression of several neurodegenerative diseases. Among them, CSF neurofilament light (NfL) protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8d1f9650cd4a2deb16a21d2268c08f
https://doaj.org/article/0775eb62e5104bb3be549fd2c1dc498f

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Is the Natural Anatomical Evolution of Type B Intramural Hematomas Reliable to Identify the Patients at Risk of Aneurysmal Progression?

Autor: Julien Mancini, Pierre-Antoine Barral, Arnaud Blanchard, Mariangela De Masi, Philippe Piquet, Laurence Bal, David Lagier, Marine Gaudry, Sonia Bolomey, Alexis Jacquier

Publikováno v: Annals of Vascular Surgery
Annals of Vascular Surgery, Elsevier Masson, 2020, 64, pp.62-70. ⟨10.1016/j.avsg.2019.11.048⟩

International audience; Background: The natural history of type B intramural hematomas is little-known. Aneurysmal progression or an aortic dissection occurs in 15 to 20% of the cases. The study of the natural anatomical evolution could help identify

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d54d29a857bcd7073e1fa83108c203
https://doi.org/10.1016/j.avsg.2019.11.048

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Sofosbuvir and risk of estimated glomerular filtration rate decline or end‐stage renal disease in patients with renal impairment

Autor: Mark Sulkowski, Laura E. Telep, Massimo Colombo, Francois Durand, K. Rajender Reddy, Eric Lawitz, Marc Bourlière, Nelson Cheinquer, Stacey Scherbakovsky, Liyun Ni, Lindsey Force, Heribert Ramroth, Anuj Gaggar, Anand P. Chokkalingam, Meghan E. Sise

Publikováno v: Alimentary Pharmacology & Therapeutics (Suppl)
Alimentary Pharmacology & Therapeutics (Suppl), 2022, 55 (9), pp.1169-1178. ⟨10.1111/apt.16830⟩

Background: Sofosbuvir, a prodrug nucleoside inhibitor of hepatitis C virus, has a predominant circulating metabolite that is renally eliminated. Whether sofosbuvir is associated with chronic kidney disease (CKD) progression is not well understood.Me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f47067c4c65c4697a03002ab8a4405
https://www.hal.inserm.fr/inserm-04050685/document

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