Zobrazeno 1 - 10
of 736
pro vyhledávání: '"MESH : Disease Models, Animal"'
Autor:
Arnaud Briat, Claire Jacques, Mélodie Malige, Laure Sudre, Geoffroy Nourissat, Philippe Auzeloux, Hans Guehring, Florent Cachin, Francis Berenbaum, Elisabeth Miot-Noirault
Publikováno v:
Scientific Reports
Scientific Reports, 2022, 12 (1), pp.8146. ⟨10.1038/s41598-022-11080-4⟩
Scientific Reports, 2022, 12 (1), pp.8146. ⟨10.1038/s41598-022-11080-4⟩
With the emergence of disease modifying osteoarthritis drugs (DMOAD), imaging methods to quantitatively demonstrate their efficacy and to monitor osteoarthritis progression at the functional level are urgently needed. Our group showed that articular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40926a3171f583abf2e142cc4fdc87bc
https://hal.archives-ouvertes.fr/hal-03699540
https://hal.archives-ouvertes.fr/hal-03699540
Autor:
Ortiz, Gabriella, Vacca, Ophélie, Bénard, Romain, Dupas, Bénédicte, Sennlaub, Florian, Guillonneau, Xavier, JA, Sahel, Tadayoni, Ramin, Rendon, Alvaro, Giocanti-Aurégan, Audrey
Publikováno v:
Molecular Vision
Molecular Vision, 2022, 25, pp.714-721
Molecular Vision, 2022, 25, pp.714-721
International audience; Purpose: The aim of this study was to define the role of dystrophin Dp71 in corneal angiogenesis.Methods: Inflammation-induced corneal neovascularization experiments were performed in Dp71-null mice and C57BL/6J wild-type mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9b445ba9c3b163131ea11da1b0813caa
https://hal-cnrs.archives-ouvertes.fr/hal-03843786
https://hal-cnrs.archives-ouvertes.fr/hal-03843786
Autor:
Małgorzata Drozd, Maria Capovilla, Florence Askenazy, Susanne Thümmler, Arnaud Fernandez, Barbara Bardoni
Publikováno v:
American Journal of Medical Genetics Part A
American Journal of Medical Genetics Part A, Wiley, 2021, 185 (6), pp.1841-1847. ⟨10.1002/ajmg.a.62155⟩
American Journal of Medical Genetics Part A, Wiley, 2021, 185 (6), pp.1841-1847. ⟨10.1002/ajmg.a.62155⟩
Childhood-Onset Schizophrenia (COS) is a very rare and severe psychiatric disorder defined by adult schizophrenia symptoms occurring before the age of 13. We report a microduplication in the 10q26.3 region including part of the Inositol Polyphosphate
Autor:
Ira Fleming, Carolyn Winston, Benjamin Kruft, Alex K. Shalek, Wolfram Goessling, Satdarshan P.S. Monga, Florian Mueller, Sungjin Ko, Udayan Apte, Chad Walesky, Kellie E. Kolb, Jake Henderson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.5785. ⟨10.1038/s41467-020-19558-3⟩
Nature Communications
Nature Communications, 2020, 11 (1), pp.5785. ⟨10.1038/s41467-020-19558-3⟩
The liver plays a central role in metabolism, protein synthesis and detoxification. It possesses unique regenerative capacity upon injury. While many factors regulating cellular proliferation during liver repair have been identified, the mechanisms b
Autor:
Isabelle Bally, Judith A. Burger, Rogier W. Sanders, M. Buisson, Wesley Gros, Pascal Poignard, Axelle Amen, Roger Le Grand, Daphna Fenel, Francis Relouzat, Guy Schoehn, Camille Bouillier, Vanessa Contreras, Nicole M. Thielens, Julien Lemaitre, Franck Fieschi, Guidenn Sulbaran, Sylvie van der Werf, Anne-Sophie Gallouet, Nathalie Dereuddre-Bosquet, Winfried Weissenhorn, Romain Marlin, Michel Thépaut, Thibaut Naninck, Delphine Guilligay, Sebastian Dergan Dylon, Marit J. van Gils, Pauline Maisonnasse, Meliawati Poniman
Publikováno v:
Cell Reports Medicine
Cell Reports Medicine, 2022, 3 (2), pp.100528. ⟨10.1016/j.xcrm.2022.100528⟩
Cell Reports Medicine, 3(2):100528. Cell Press
Cell Reports Medicine, 2022, 3 (2), pp.100528. ⟨10.1016/j.xcrm.2022.100528⟩
Cell Reports Medicine, 3(2):100528. Cell Press
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused an ongoing global health crisis. Here, we present as a vaccine candidate synthetic SARS-CoV-2 spike (S) glycoprotein-coated lipid vesicles that resemble virus-like p
Autor:
Kenigsbuch, Mor, Bost, Pierre, Halevi, Shahar, Chang, Yuzhou, Chen, Shuo, Ma, Qin, Hajbi, Renana, Schwikowski, Benno, Bodenmiller, Bernd, Fu, Hongjun, Schwartz, Michal, Amit, Ido
Publikováno v:
Nature Neuroscience, 25 (7)
Nat Neurosci
Nature Neuroscience
Nature Neuroscience, 2022, 25 (7), pp.876-886. ⟨10.1038/s41593-022-01104-7⟩
Nat Neurosci
Nature Neuroscience
Nature Neuroscience, 2022, 25 (7), pp.876-886. ⟨10.1038/s41593-022-01104-7⟩
Alzheimer’s disease (AD) is a complex neurodegenerative disease, perturbing neuronal and non-neuronal cell populations. In this study, using single-cell transcriptomics, we mapped all non-immune, non-neuronal cell populations in wild-type and AD mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4990374e050ef17c30921b049575e0
Autor:
Martine Guillermier, Carole Escartin, Océane Guillemaud, Alexis-Pierre Bemelmans, Charlène Joséphine, Gilles Bonvento, Emmanuel Brouillet, Kelly Ceyzériat, Thomas Saint-Georges, Philippe Hantraye, Maria-Angeles Carrillo-de Sauvage, Karine Cambon, Sueva Bernier, Fanny Petit, Lucile Ben Haim, Anne-Sophie Hérard
Publikováno v:
Neurobiology of Aging
Neurobiology of Aging, Elsevier, 2020, 90, pp.135-146. ⟨10.1016/j.neurobiolaging.2020.02.010⟩
Neurobiology of Aging, 2020, 90, pp.135-146. ⟨10.1016/j.neurobiolaging.2020.02.010⟩
Neurobiology of Aging, Elsevier, 2020, 90, pp.135-146. ⟨10.1016/j.neurobiolaging.2020.02.010⟩
Neurobiology of Aging, 2020, 90, pp.135-146. ⟨10.1016/j.neurobiolaging.2020.02.010⟩
In Alzheimer disease (AD), astrocytes undergo complex changes and become reactive. The consequences of this reaction are still unclear. To evaluate the net impact of reactive astrocytes in AD, we recently developed viral vectors targeting astrocytes
Autor:
Mindy Tsai, Camille Petitfils, Nicolas Cenac, Stephen J. Galli, Riccardo Sibilano, Xinzhong Dong, Laurent L. Reber, Nicolas Gaudenzio, Lilian Basso, Philipp Starkl, Nadine Serhan, Chrystelle Bonnart, Thomas Marichal, James Meixiong
Publikováno v:
Nature immunology, vol 20, iss 11
Nature Immunology
Nature Immunology, Nature Publishing Group, 2019, 20 (11), pp.1435-1443. ⟨10.1038/s41590-019-0493-z⟩
Nature immunology
Cellular and Molecular Immunology
Nature Immunology, 2019, 20 (11), pp.1435-1443. ⟨10.1038/s41590-019-0493-z⟩
Nature Immunology
Nature Immunology, Nature Publishing Group, 2019, 20 (11), pp.1435-1443. ⟨10.1038/s41590-019-0493-z⟩
Nature immunology
Cellular and Molecular Immunology
Nature Immunology, 2019, 20 (11), pp.1435-1443. ⟨10.1038/s41590-019-0493-z⟩
International audience; Allergic skin diseases, such as atopic dermatitis, are clinically characterized by severe itching and type 2 immunity-associated hypersensitivity to widely distributed allergens, including those derived from house dust mites (
Autor:
Schwing, Aurélie, Pisani, Didier, Pomares, Christelle, Majoor, Alissa, Lacas-Gervais, Sandra, Jager, Jennifer, Lemichez, Emmanuel, Marty, Pierre, Boyer, Laurent, Michel, Grégory
Publikováno v:
Scientific Reports
Scientific Reports, 2021, 11 (1), pp.21275. ⟨10.1038/s41598-021-00443-y⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports, 2021, 11 (1), pp.21275. ⟨10.1038/s41598-021-00443-y⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
International audience; Leishmania infantum is the causative agent of visceral leishmaniasis transmitted by the bite of female sand flies. According to the WHO, the estimated annual incidence of leishmaniasis is one million new cases, resulting in 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d40324873466a431fa9416398403f539
https://hal-pasteur.archives-ouvertes.fr/pasteur-03744940
https://hal-pasteur.archives-ouvertes.fr/pasteur-03744940
Autor:
Lena Feige, Inés Sáenz-de-Santa-María, Beatrice Regnault, Rachel Lavenir, Anthony Lepelletier, Ala Halacu, Randrianasolo Rajerison, Sylvie Diop, Chhor Nareth, Jean-Marc Reynes, Philippe Buchy, Hervé Bourhy, Laurent Dacheux
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, 2021, 11, pp.761074. ⟨10.3389/fcimb.2021.761074⟩
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Frontiers in Cellular and Infection Microbiology, 2021, 11, pp.761074. ⟨10.3389/fcimb.2021.761074⟩
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
International audience; Rabies virus (RABV), the causative agent for rabies disease is still presenting a major public health concern causing approximately 60,000 deaths annually. This neurotropic virus (genus Lyssavirus , family Rhabdoviridae ) indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bc3a20a1d13b3e41534a67d8814e6ecc
https://hal-pasteur.archives-ouvertes.fr/pasteur-03681912
https://hal-pasteur.archives-ouvertes.fr/pasteur-03681912