Zobrazeno 1 - 10
of 170
pro vyhledávání: '"MESH : DNA Methylation"'
Autor:
Magali Charvin, Thierry Halter, Romain Blanc-Mathieu, Pierre Barraud, Magali Aumont-Nicaise, François Parcy, Lionel Navarro
Publikováno v:
Plant Physiology
Plant Physiology, 2023, 192 (1), pp.77-84. ⟨10.1093/plphys/kiad069⟩
Plant Physiology, 2023, 192 (1), pp.77-84. ⟨10.1093/plphys/kiad069⟩
DNA methylation is an epigenetic mark that fine-tunes gene expression, notably by negatively or positively regulating transcription factor (TF)-DNA binding. In plants, DNA methylation has primarily been shown to inhibit TF-DNA binding. However, littl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cddfafd797eae3befdcb62bba96afdc
https://hal.science/hal-04097425/document
https://hal.science/hal-04097425/document
Autor:
Elmar W. Tobi, Diana L. Juvinao-Quintero, Justiina Ronkainen, Raffael Ott, Rossella Alfano, Mickaël Canouil, Madelon L. Geurtsen, Amna Khamis, Leanne K. Küpers, Ives Y. Lim, Patrice Perron, Giancarlo Pesce, Johanna Tuhkanen, Anne P. Starling, Toby Andrew, Elisabeth Binder, Robert Caiazzo, Jerry K.Y. Chan, Romy Gaillard, Peter D. Gluckman, Elina Keikkala, Neerja Karnani, Sanna Mustaniemi, Tim S. Nawrot, François Pattou, Michelle Plusquin, Violeta Raverdy, Kok Hian Tan, Evangelia Tzala, Katri Raikkonen, Christiane Winkler, Anette-G. Ziegler, Isabella Annesi-Maesano, Luigi Bouchard, Yap Seng Chong, Dana Dabelea, Janine F. Felix, Barbara Heude, Vincent W.V. Jaddoe, Jari Lahti, Brigitte Reimann, Marja Vääräsmäki, Amélie Bonnefond, Philippe Froguel, Sandra Hummel, Eero Kajantie, Marjo-Riita Jarvelin, Regine P.M. Steegers-Theunissen, Caitlin G. Howe, Marie-France Hivert, Sylvain Sebert
Publikováno v:
Diabetes Care
Diabetes Care, 2022, 45 (3), pp.614-623. ⟨10.2337/dc21-1701⟩
Diabetes Care, 45(3), 614-623. American Diabetes Association Inc.
Diabetes Care 45, 614-623 (2022)
Diabetes Care, 2022, 45 (3), pp.614-623. ⟨10.2337/dc21-1701⟩
Diabetes Care, 45(3), 614-623. American Diabetes Association Inc.
Diabetes Care 45, 614-623 (2022)
OBJECTIVE Maternal glycemic dysregulation during pregnancy increases the risk of adverse health outcomes in her offspring; a risk thought to be linearly related to maternal hyperglycemia. It is hypothesized that changes in offspring DNA methylation (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bc9777913c3a7ff45f03e99fa4e8e9
https://hal.umontpellier.fr/hal-03676276
https://hal.umontpellier.fr/hal-03676276
Autor:
Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird
Publikováno v:
Cancer Discovery
Cancer Discovery, In press, ⟨10.1158/2159-8290.CD-21-0205⟩
Cancer Discovery, 12, 2158-2179
Cancer Discovery, 12, 9, pp. 2158-2179
Cancer Discovery, In press, ⟨10.1158/2159-8290.CD-21-0205⟩
Cancer Discovery, 12, 2158-2179
Cancer Discovery, 12, 9, pp. 2158-2179
Small cell lung cancer (SCLC) is the most fatal form of lung cancer, with dismal survival, limited therapeutic options, and rapid development of chemoresistance. We identified the lysine methyltransferase SMYD3 as a major regulator of SCLC sensitivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a6f369ad5cbcb85ed2d339d7aa9050
https://cnrs.hal.science/hal-03759864/document
https://cnrs.hal.science/hal-03759864/document
A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome
Autor:
Soret, Perrine, Le Dantec, Christelle, Desvaux, Emiko, Foulquier, Nathan, Chassagnol, Bastien, Hubert, Sandra, Christophe, Jamin, Barturen, Guillermo, Desachy, Guillaume, Devauchelle-Pensec, Valérie, Boudjeniba, Cheïma, Cornec, Divi, Saraux, Alain, Jousse-Joulin, Sandrine, Barbarroja, Nuria, Rodríguez-Pintó, Ignasi, de Langhe, Ellen, Beretta, Lorenzo, Chizzolini, Carlo, Kovács, László, Witte, Torsten, Bettacchioli, Eléonore, Buttgereit, Anne, Makowska, Zuzanna, Lesche, Ralf, Borghi, Maria Orietta, Martin, Javier, Courtade-Gaiani, Sophie, Xuereb, Laura, Guedj, Mickaël, Moingeon, Philippe, Alarcón-Riquelme, Marta, Laigle, Laurence, Pers, Jacques-Olivier, Vigone, Barbara, Lauwerys, Bernard, Maudoux, Anne-Lise, Vasconcelos, Carlos, Tavares, Ana, Faria, Raquel, Brandão, Mariana, Campar, Ana, Marinho, António, Farinha, Fátima, Almeida, Isabel, Gonzalez-Gay Mantecón, Miguel Angel, Blanco Alonso, Ricardo, Corrales Martínez, Alfonso, Cervera, Ricard, Espinosa, Gerard, Lories, Rik, Hunzelmann, Nicolas, Belz, Doreen, Baerlecken, Niklas, Stummvoll, Georg, Zauner, Michael, Lehner, Michaela, Collantes, Eduardo, Ortega-Castro, Rafaela, Aguirre-Zamorano, Ma Angeles, Escudero-Contreras, Alejandro, Castro-Villegas, Ma Carmen, Jiménez Gómez, Yolanda, Ortego, Norberto, Fernández Roldán, María Concepción, Raya, Enrique, Jiménez Moleón, Inmaculada, de Ramon, Enrique, Díaz Quintero, Isabel, Meroni, Pier Luigi, Gerosa, Maria, Schioppo, Tommaso, Artusi, Carolina, Zuber, Aleksandra, Wynar, Donatienne, Balog, Attila, Deák, Magdolna, Bocskai, Márta, Dulic, Sonja, Kádár, Gabriella, Hiepe, Falk, Thiel, Silvia, Rodriguez Maresca, Manuel, López-Berrio, Antonio, Aguilar-Quesada, Rocío, Navarro-Linares, Héctor, Ioannou, Yiannis, Chamberlain, Chris, Marovac, Jacqueline, Alarcón Riquelme, Marta, Gomes Anjos, Tania, Marañón, Concepción, Le Lann, Lucas, Simon, Quentin, Rouvière, Bénédicte, Varela, Nieves, Muchmore, Brian, Dufour, Aleksandra, Alvarez, Montserrat, Cremer, Jonathan, Lopez-Pedrera, Chary, Gerl, Velia, Khodadadi, Laleh, Cheng, Qingyu, de Groof, Aurélie, Ducreux, Julie, Trombetta, Elena, Li, Tianlu, Alvarez-Errico, Damiana, Kniesch, Katja, Azevedo, Nancy, Neves, Esmeralda, Rao, Sambasiva, Jouve, Pierre-Emmanuel
Publikováno v:
Nature Communications
Nature Communications, 2021, 12 (1), pp.3523. ⟨10.1038/s41467-021-23472-7⟩
Nature Communications, 2021, 12 (1), pp.3523. ⟨10.1038/s41467-021-23472-7⟩
International audience; Abstract There is currently no approved treatment for primary Sjögren’s syndrome, a disease that primarily affects adult women. The difficulty in developing effective therapies is -in part- because of the heterogeneity in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1398::61506dd34eed6fb273e9c83af11f3311
https://hal.univ-brest.fr/hal-03301637
https://hal.univ-brest.fr/hal-03301637
Autor:
Alexandre G. Casanova, Li-Sheng Zhang, Ning Tsao, Brittany A. Townley, Nima Mosammaparast, Joshua R. Brickner, Chuan He, John A. Tainer, Rebecca Rodell, Tanveer Ahmad, Matthew D. Wood, Hua Sun, Jennifer M. Soll, Nicolas Reynoird, Clement Oyeniran, Alessandro Vindigni, Adit Ganguly, Albino Bacolla, Valentina Lukinović
Publikováno v:
Mol Cell
Molecular Cell
Molecular Cell, 2021, 81 (20), pp.4228-4242.e8. ⟨10.1016/j.molcel.2021.09.024⟩
Molecular Cell
Molecular Cell, 2021, 81 (20), pp.4228-4242.e8. ⟨10.1016/j.molcel.2021.09.024⟩
International audience; Summary Central to genotoxic responses is their ability to sense highly specific signals to activate the appropriate repair response. We previously reported that the activation of the ASCC-ALKBH3 repair pathway is exquisitely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22341f9c122e9653e82bea7080278c0
https://europepmc.org/articles/PMC8931856/
https://europepmc.org/articles/PMC8931856/
Autor:
Olivier Hermine, Vahid Asnafi, Izabela Bialuk, Marcia Bellon, Lee Ratner, Ambroise Marçais, Michael N. Petrus, Thomas A. Waldmann, Genoveffa Franchini, Toshiki Watanabe, Antoine Gessain, Masao Matsuoka, Christophe Nicot, Achiléa L. Bittencourt, Lourdes Farre, Veronica Galli, Xue Tao Bai
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Molecular Cancer
Molecular Cancer, 2021, 20 (1), pp.86. ⟨10.1186/s12943-021-01370-2⟩
Molecular Cancer, Vol 20, Iss 1, Pp 1-15 (2021)
Universidad de Barcelona
Molecular Cancer
Molecular Cancer, 2021, 20 (1), pp.86. ⟨10.1186/s12943-021-01370-2⟩
Molecular Cancer, Vol 20, Iss 1, Pp 1-15 (2021)
Background Human T cell Leukemia virus type 1 (HTLV-I) is etiologically linked to adult T cell leukemia/lymphoma (ATL) and an inflammatory neurodegenerative disease called HTLV-I-associated myelopathy or tropical spastic paraparesis (HAM/TSP). The ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6510393e031c514bb0b9c0e9b58acbdb
http://hdl.handle.net/2445/178671
http://hdl.handle.net/2445/178671
Autor:
Guillaume Velasco, Damien Ulveling, Sophie Rondeau, Pauline Marzin, Motoko Unoki, Valérie Cormier-Daire, Claire Francastel
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences, 2021, 22 (7), pp.3735. ⟨10.3390/ijms22073735⟩
International Journal of Molecular Sciences, MDPI, 2021, 22 (7), pp.3735. ⟨10.3390/ijms22073735⟩
International Journal of Molecular Sciences, Vol 22, Iss 3735, p 3735 (2021)
Volume 22
Issue 7
International Journal of Molecular Sciences, 2021, 22 (7), pp.3735. ⟨10.3390/ijms22073735⟩
International Journal of Molecular Sciences, MDPI, 2021, 22 (7), pp.3735. ⟨10.3390/ijms22073735⟩
International Journal of Molecular Sciences, Vol 22, Iss 3735, p 3735 (2021)
International audience; DNA methylation (DNAme) profiling is used to establish specific biomarkers to improve the diagnosis of patients with inherited neurodevelopmental disorders and to guide mutation screening. In the specific case of mendelian dis
Autor:
Xu, Cheng-Jian, Gruzieva, Olena, Qi, CanCan, Esplugues, Ana, Gehring, Ulrike, Bergström, Anna, Mason, Dan, Chatzi, Leda, Porta, Daniela, Lodrup Carlsen, Karin, Baïz, Nour, Madore, Anne-Marie, Alenius, Harri, van Rijkom, Bianca, Jankipersadsing, Soesma, Van Der Vlies, Pieter, Kull, Inger, Van Hage, Marianne, Bustamante, Mariona, Lertxundi, Aitana, Torrent, Matias, Santorelli, Gillian, Fantini, Maria Pia, Hovland, Vegard, Pesce, Giancarlo, Fyhrquist, Nanna, Laatikainen, Tiina, Nawijn, Martijn, Li, Yang, Wijmenga, Cisca, Netea, Mihai, Bousquet, Jean, Anto, Josep, Laprise, Catherine, Haahtela, Tari, Annesi-Maesano, Isabella, Carlsen, Kai-Håkon, Gori, Davide, Kogevinas, Manolis, Wright, John, Söderhäll, Cilla, Vonk, Judith, Sunyer, Jordi, Melén, Erik, Koppelman, Gerard, Fantini, Maria
Publikováno v:
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, Elsevier, 2021, 147 (3), pp.1031-1040. ⟨10.1016/j.jaci.2020.11.044⟩
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
J Allergy Clin Immunol
Addi. Archivo Digital para la Docencia y la Investigación
instname
Journal of Allergy and Clinical Immunology, 147, 3, pp. 1031-1040
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Journal of Allergy and Clinical Immunology, 147, 1031-1040
r-FISABIO. Repositorio Institucional de Producción Científica
Journal of Allergy and Clinical Immunology, 147(3), 1031-1040. MOSBY-ELSEVIER
Journal of Allergy and Clinical Immunology, Elsevier, 2021, 147 (3), pp.1031-1040. ⟨10.1016/j.jaci.2020.11.044⟩
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
J Allergy Clin Immunol
Addi. Archivo Digital para la Docencia y la Investigación
instname
Journal of Allergy and Clinical Immunology, 147, 3, pp. 1031-1040
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Journal of Allergy and Clinical Immunology, 147, 1031-1040
r-FISABIO. Repositorio Institucional de Producción Científica
Journal of Allergy and Clinical Immunology, 147(3), 1031-1040. MOSBY-ELSEVIER
Contains fulltext : 232514.pdf (Publisher’s version ) (Open Access) BACKGROUND: Differential DNA methylation associated with allergy might provide novel insights into the shared or unique etiology of asthma, rhinitis, and eczema. OBJECTIVE: We soug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d60c3c00955deb9edc32bf0fa143b1f
https://hal.sorbonne-universite.fr/hal-03477217/file/PIIS0091674920317668.pdf
https://hal.sorbonne-universite.fr/hal-03477217/file/PIIS0091674920317668.pdf
Autor:
Anna Bergström, Nathanaël Lemonnier, Marie Standl, Inger Kull, Aitana Lertxundi, Simon Kebede Merid, Joachim Heinrich, Josep M. Antó, Jordi Sunyer, Olena Gruzieva, Jean Bousquet, Åsa M. Wheelock, Erik Melén, Gerard H. Koppelman, Mariona Bustamante, Daniel Aguilar, Loreto Santa-Marina
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
Environ. Int. 146:106248 (2021)
Environment International, Vol 146, Iss, Pp 106248-(2021)
Environment international, 146:106248. PERGAMON-ELSEVIER SCIENCE LTD
Environment International
Environment International, 2021, 146, pp.106248. ⟨10.1016/j.envint.2020.106248⟩
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
instname
Environ. Int. 146:106248 (2021)
Environment International, Vol 146, Iss, Pp 106248-(2021)
Environment international, 146:106248. PERGAMON-ELSEVIER SCIENCE LTD
Environment International
Environment International, 2021, 146, pp.106248. ⟨10.1016/j.envint.2020.106248⟩
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Air pollution has been associated with adverse health effects across the life-course. Although underlying mechanisms are unclear, several studies suggested pollutant-induced changes in transcriptomic profiles. In this meta-analysis of transcriptome-w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e72c85a175870eabb9911faad2ce10
http://hdl.handle.net/10810/49969
http://hdl.handle.net/10810/49969
A new molecular classification to drive precision treatment strategies in primary Sjögren's syndrome
Autor:
Soret, Perrine, Le Dantec, Christelle, Desvaux, Emiko, Foulquier, Nathan, Chassagnol, Bastien, Hubert, Sandra, Jamin, Christophe, Barturen, Guillermo, Desachy, Guillaume, Devauchelle-Pensec, Valérie, Boudjeniba, Cheïma, Cornec, Divi, Saraux, Alain, Jousse-Joulin, Sandrine, Barbarroja, Nuria, Rodríguez-Pintó, Ignasi, De Langhe, Ellen, Beretta, Lorenzo, Chizzolini, Carlo, Kovács, László, Witte, Torsten, Bettacchioli, Eléonore, Buttgereit, Anne, Makowska, Zuzanna, Lesche, Ralf, Borghi, Maria Orietta, Martin, Javier, Courtade-Gaiani, Sophie, Xuereb, Laura, Guedj, Mickaël, Moingeon, Philippe, Alarcón-Riquelme, Marta, Laigle, Laurence, Pers, Jacques-Olivier, Vigone, Barbara, Lauwerys, Bernard, Maudoux, Anne-Lise, Vasconcelos, Carlos, Tavares, Ana, Faria, Raquel, Brandão, Mariana, Campar, Ana, Marinho, António, Farinha, Fátima, Almeida, Isabel, Gonzalez-Gay Mantecón, Miguel Angel, Blanco Alonso, Ricardo, Corrales Martínez, Alfonso, Cervera, Ricard, Espinosa, Gerard, Lories, Rik, Hunzelmann, Nicolas, Belz, Doreen, Baerlecken, Niklas, Stummvoll, Georg, Zauner, Michael, Lehner, Michaela, Collantes, Eduardo, Ortega-Castro, Rafaela, Aguirre-Zamorano, Ma Angeles, Escudero-Contreras, Alejandro, Castro-Villegas, Ma Carmen, Jiménez Gómez, Yolanda, Ortego, Norberto, Fernández Roldán, María Concepción, Raya, Enrique, Jiménez Moleón, Inmaculada, de Ramon, Enrique, Díaz Quintero, Isabel, Meroni, Pier Luigi, Gerosa, Maria, Schioppo, Tommaso, Artusi, Carolina, Zuber, Aleksandra, Wynar, Donatienne, Balog, Attila, Deák, Magdolna, Bocskai, Márta, Dulic, Sonja, Kádár, Gabriella, Hiepe, Falk, Thiel, Silvia, Rodriguez Maresca, Manuel, López-Berrio, Antonio, Aguilar-Quesada, Rocío, Navarro-Linares, Héctor, Ioannou, Yiannis, Chamberlain, Chris, Marovac, Jacqueline, Alarcón Riquelme, Marta, Gomes Anjos, Tania, Marañón, Concepción, Le Lann, Lucas, Simon, Quentin, Rouvière, Bénédicte, Varela, Nieves, Muchmore, Brian, Dufour, Aleksandra, Alvarez, Montserrat, Cremer, Jonathan, Lopez-Pedrera, Chary, Gerl, Velia, Khodadadi, Laleh, Cheng, Qingyu, De Groof, Aurélie, Ducreux, Julie, Trombetta, Elena, Li, Tianlu, Alvarez-Errico, Damiana, Kniesch, Katja, Azevedo, Nancy, Neves, Esmeralda, Rao, Sambasiva, Jouve, Pierre-Emmanuel
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3523. ⟨10.1038/s41467-021-23472-7⟩
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3523. ⟨10.1038/s41467-021-23472-7⟩
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Dipòsit Digital de la UB
Universidad de Barcelona
There is currently no approved treatment for primary Sjögren’s syndrome, a disease that primarily affects adult women. The difficulty in developing effective therapies is -in part- because of the heterogeneity in the clinical manifestation and pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5182e71983a3c820bc2eed151f2178
http://hdl.handle.net/10261/250682
http://hdl.handle.net/10261/250682