Zobrazeno 1 - 6
of 6
pro vyhledávání: '"MESH : Cytotoxins"'
Autor:
Laurent Meijer, Gordon B. Mills, Khandan Keyomarsi, Donald H. Lambert, Laura A. Lambert, Na Qiao, Kelly K. Hunt
Publikováno v:
Cancer Research
Cancer Research, 2008, 68 (19), pp.7966-74. ⟨10.1158/0008-5472.CAN-08-1333⟩
Cancer Research, American Association for Cancer Research, 2008, 68 (19), pp.7966-74. ⟨10.1158/0008-5472.CAN-08-1333⟩
Cancer Research, American Association for Cancer Research, 2008, 68 (19), pp.7966-74. 〈10.1158/0008-5472.CAN-08-1333〉
Cancer Research, 2008, 68 (19), pp.7966-74. ⟨10.1158/0008-5472.CAN-08-1333⟩
Cancer Research, American Association for Cancer Research, 2008, 68 (19), pp.7966-74. ⟨10.1158/0008-5472.CAN-08-1333⟩
Cancer Research, American Association for Cancer Research, 2008, 68 (19), pp.7966-74. 〈10.1158/0008-5472.CAN-08-1333〉
Doxorubicin is a genotoxic chemotherapy agent used in treatment of a wide variety of cancers. Significant clinical side effects, including cardiac toxicity and myelosuppression, severely limit the therapeutic index of this commonly used agent and met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264c11b00fcf711983860e67cc552593
https://europepmc.org/articles/PMC2561224/
https://europepmc.org/articles/PMC2561224/
Publikováno v:
Toxicology in Vitro
Toxicology in Vitro, Elsevier, 2009, 23 (7), pp.1412-21. ⟨10.1016/j.tiv.2009.07.011⟩
Toxicology in Vitro, Elsevier, 2009, 23 (7), pp.1412-21. ⟨10.1016/j.tiv.2009.07.011⟩
International audience; Bioinformatics and traditional medicine can be used in discovery and design of novel candidate drugs to efficient cancer chemotherapy. In this study, similarity search tools employed to screen and introduce novel herbs with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0e6b8fe5e3926a4aa10ab982df10fd
https://hal-riip.archives-ouvertes.fr/pasteur-00753306/document
https://hal-riip.archives-ouvertes.fr/pasteur-00753306/document
Autor:
Alain Pierré, Thomas Gaslonde, Christian Bailly, François Tillequin, Stéphane Léonce, Angèle Chiaroni, William Laine, Bruno Pfeiffer, Sabine Depauw, Sylvie Michel, Laurence Kraus-Berthier, Marie-Hélène David-Cordonnier, Gaëlle Lenglet
Publikováno v:
Molecular Pharmacology
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2009, 76 (6), pp.1172-85. ⟨10.1124/mol.109.057554⟩
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2009, 76 (6), pp.1172-85. ⟨10.1124/mol.109.057554⟩
International audience; S23906-1 is a benzo[b]acronycine derivative acting as a DNA-alkylating agent through covalent bonding to the exocyclic amino group of guanines and subsequent local opening of the DNA helix. This compound was selected for phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e064481ad301d51fb458ad8278ecfd41
https://pubmed.ncbi.nlm.nih.gov/19752199
https://pubmed.ncbi.nlm.nih.gov/19752199
Autor:
Conlon, J Michael, Raza, Haider, Coquet, Laurent, Jouenne, Thierry, Leprince, Jérôme, Vaudry, Hubert, King, Jay, Conlon, J. Michael, King, Jay.
Publikováno v:
Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology
Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology, Elsevier, 2009, 150 (2), pp.150-154. ⟨10.1016/j.cbpc.2009.04.003⟩
Comparative Biochemistry and Physiology-Part C: Toxicology and Pharmacology, Elsevier, 2009, 150 (2), pp.150-154. ⟨10.1016/j.cbpc.2009.04.003⟩
International audience; Peptide-based defenses of ranid frogs from Mexico and Central America have been studied in much less detail than those from North America. Peptides belonging to the brevinin-1 (5 peptides), palustrin-2 (1 peptide), and ranatue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf4fa3897adc639a7d7706d205d7540
https://pubmed.ncbi.nlm.nih.gov/19379837
https://pubmed.ncbi.nlm.nih.gov/19379837
Autor:
Emmanuel Nowak, Nathalie B. Viget, Florence Ader, B. Guery, R. Le Berre, Benoît Polack, Bertrand Toussaint, Karine Faure, Eric Kipnis, Philippe Gosset, Olivier Epaulard
Publikováno v:
Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2005, 73 (7), pp.4263-71. ⟨10.1128/IAI.73.7.4263-4271.2005⟩
Europe PubMed Central
Infection and Immunity, American Society for Microbiology, 2005, 73 (7), pp.4263-71. ⟨10.1128/IAI.73.7.4263-4271.2005⟩
Europe PubMed Central
The type III secretion system (TTSS) is a specialized cytotoxin-translocating apparatus of gram-negative bacteria which is involved in lung injury, septic shock, and a poor patient outcome. Recent studies have attributed these effects mainly to the E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78d89f6417e1bda60f4ed4b8e5c2562
https://hal.archives-ouvertes.fr/hal-00397973
https://hal.archives-ouvertes.fr/hal-00397973
Autor:
Patrick Munro, Emmanuel Lemichez
Publikováno v:
Scopus-Elsevier
Current Topics in Microbiology and Immunology
Current Topics in Microbiology and Immunology, Springer Verlag (Germany), 2005, 291, pp.177-90
Bacterial Virulence Factors and Rho GTPases ISBN: 9783540238652
Current Topics in Microbiology and Immunology
Current Topics in Microbiology and Immunology, Springer Verlag (Germany), 2005, 291, pp.177-90
Bacterial Virulence Factors and Rho GTPases ISBN: 9783540238652
The CNF1 toxin is produced by some uropathogenic (UPECs) andmeningitis-causing Escherichia coli strains. It belongs to a large family of bacterial virulence factors and toxins modifying cellular regulators of the actin cytoskeleton, namely the Rho GT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12827813ae0a7e6e8de86da0f53a715
http://www.scopus.com/inward/record.url?eid=2-s2.0-18744416844&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-18744416844&partnerID=MN8TOARS