The pore structure of Clostridium perfringens epsilon toxin

Autor: Savva, Christos, Clark, Alice, Naylor, Claire, Popoff, Michel, Moss, David, Basak, Ajit, Titball, Richard, Bokori-Brown, Monika

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.2641. ⟨10.1038/s41467-019-10645-8⟩
Nature Communications, 2019, 10 (1), pp.2641. ⟨10.1038/s41467-019-10645-8⟩

Epsilon toxin (Etx), a potent pore forming toxin (PFT) produced by Clostridium perfringens, is responsible for the pathogenesis of enterotoxaemia of ruminants and has been suggested to play a role in multiple sclerosis in humans. Etx is a member of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::03b5647c6160a8077e0ad0ee01cd113c
https://hal-pasteur.archives-ouvertes.fr/pasteur-02454060

Characterization of Clostridium Perfringens Isolates Collected from Three Agricultural Biogas Plants over a One-Year Period

Autor: Derongs, Lorine, Druilhe, Céline, Ziebal, Christine, Le Maréchal, Caroline, Pourcher, Anne-Marie

Publikováno v: International Journal of Environmental Research and Public Health
Volume 17
Issue 15
International Journal of Environmental Research and Public Health, Vol 17, Iss 5450, p 5450 (2020)
International Journal of Environmental Research and Public Health, MDPI, 2020, 17 (15), ⟨10.3390/ijerph17155450⟩

Digestate produced by agricultural biogas plants (BGPs) may contain pathogenic bacteria. Among them, Clostridium perfringens deserves particular attention due to its ability to grow under anaerobic conditions and persist in amended soil. The aim of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1beaeeb668a219dd9978eb6d7867ded2

Clostridium perfringens Enterotoxin: The Toxin Forms Highly Cation-Selective Channels in Lipid Bilayers

Autor: Michel R. Popoff, Roland Benz

Publikováno v: Toxins
Toxins, 2018, 10 (9), pp.341. ⟨10.3390/toxins10090341⟩
Toxins, Vol 10, Iss 9, p 341 (2018)
Toxins, MDPI, 2018, 10 (9), pp.341. ⟨10.3390/toxins10090341⟩
Volume 10
Issue 9

International audience; One of the numerous toxins produced by Clostridium perfringens is Clostridium perfringens enterotoxin (CPE), a polypeptide with a molecular mass of 35.5 kDa exhibiting three different domains. Domain one is responsible for rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101549017a9a8897603b6654bbaf99ef
https://hal-pasteur.archives-ouvertes.fr/pasteur-02448636

Highly sensitive sandwich immunoassay and immunochromatographic test for the detection of Clostridial epsilon toxin in complex matrices

Autor: Cécile, Féraudet-Tarisse, Christelle, Mazuet, Serge, Pauillac, Maren, Krüger, Caroline, Lacroux, Michel R, Popoff, Brigitte G, Dorner, Olivier, Andréoletti, Marc, Plaisance, Hervé, Volland, Stéphanie, Simon

Publikováno v: PLoS ONE
PLoS ONE, 2017, 12 (7), pp.e0181013. ⟨10.1371/journal.pone.0181013⟩
PLoS ONE, Vol 12, Iss 7, p e0181013 (2017)
PLoS ONE, Public Library of Science, 2017, 12 (7), pp.e0181013. ⟨10.1371/journal.pone.0181013⟩
Plos One 7 (12), e0181013. (2017)

International audience; Epsilon toxin is one of the four major toxins of Clostridium perfringens. It is the third most potent clostridial toxin after botulinum and tetanus toxins and is thus considered as a potential biological weapon classified as c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1241e1c405a800762d094c2904d51dee
https://hal-pasteur.archives-ouvertes.fr/pasteur-01570220

Environmental Response and Autoregulation of Clostridium difficile TxeR, a Sigma Factor for Toxin Gene Expression

Autor: Lisa Barroso, Pauline Howarth, Julian I. Rood, Tracy D. Wilkins, Nagraj Mani, Dena Lyras, Bruno Dupuy, Abraham L. Sonenshein

Publikováno v: Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2002, 184 (21), pp.5971-5978. ⟨10.1128/jb.184.21.5971-5978.2002⟩
Monash University
Journal of Bacteriology, 2002, 184 (21), pp.5971-5978. ⟨10.1128/jb.184.21.5971-5978.2002⟩

TxeR, a sigma factor that directs Clostridium difficile RNA polymerase to recognize the promoters of two major toxin genes, was shown to stimulate its own synthesis. Whether expressed in C. difficile , Clostridium perfringens , or Escherichia coli ,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6adc4b9e2e88ae49658315a8c7c3ef5
https://doi.org/10.1128/jb.184.21.5971-5978.2002