CD40 Ligand Protects from TRAIL-Induced Apoptosis in Follicular Lymphomas through NF-κB Activation and Up-Regulation of c-FLIP and Bcl-xL

Autor: Patricia Amé-Thomas, Thierry Lamy, Olivier Micheau, Alexandre Morizot, Marion Travert, G. Semana, Thierry Guillaudeux, Céline Pangault, Thierry Fest, Karin Tarte

Publikováno v: Scopus-Elsevier
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 181 (2), pp.1001-11. 〈10.4049/​jimmunol.181.2.1001〉
Journal of Immunology, 2008, 181 (2), pp.1001-11. ⟨10.4049/jimmunol.181.2.1001⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 181 (2), pp.1001-11. ⟨10.4049/jimmunol.181.2.1001⟩
ResearcherID

The TNF family member TRAIL is emerging as a promising cytotoxic molecule for antitumor therapy. However, its mechanism of action and the possible modulation of its effect by the microenvironment in follicular lymphomas (FL) remain unknown. We show h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b80bc47423b847c8aa454be74819775
https://doi.org/10.4049/jimmunol.181.2.1001

The Ribonucleotide Reductase R1 Subunits of Herpes Simplex Virus 1 and 2 Protect Cells against Poly(I · C)-Induced Apoptosis

Autor: Florent Dufour, Angela Pearson, Yves Langelier, Luc Bertrand, Nathalie Grandvaux

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2011, 85 (17), pp.8689-701. ⟨10.1128/JVI.00362-11⟩

We recently provided evidence that the ribonucleotide reductase R1 subunits of herpes simplex virus types 1 and 2 (HSV-1 and -2) protect cells against tumor necrosis factor alpha- and Fas ligand-induced apoptosis by interacting with caspase 8. Double

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf3002434d6a57e3fc9081293940de6
https://doi.org/10.1128/jvi.00362-11

Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level

Autor: Delphine Merino, Eric Solary, Guillaume Jacquemin, Philippe Saas, Najoua Lalaoui, Elisabetta Iessi, Olivier Micheau, Carmen Garrido, Bruno Chauffert, Florence Bouyer, David Lanneau, Virginie Granci, Alexandre Morizot

Publikováno v: Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, 2010, ⟨10.1038/cdd.2010.144⟩
Cell Death and Differentiation, Nature Publishing Group, 2011, 18 (4), pp.700-11. ⟨10.1038/cdd.2010.144⟩
Cell Death and Differentiation, Nature Publishing Group, 2011, 18 (4), pp.700-11. 〈10.1038/cdd.2010.144〉
Cell Death and Differentiation, 2011, 18 (4), pp.700-11. ⟨10.1038/cdd.2010.144⟩

International audience; TNF-related apoptosis-inducing ligand or Apo2L (Apo2L/TRAIL) is a promising anti-cancer drug owing to its ability to trigger apoptosis by binding to TRAIL-R1 or TRAIL-R2, two membrane-bound receptors that are often expressed b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13b58e3ad4241a2e423ba9d6fcc3291
https://hal.archives-ouvertes.fr/hal-00592295

E2F1 induces apoptosis and sensitizes human lung adenocarcinoma cells to death-receptor-mediated apoptosis through specific downregulation of c-FLIP(short)

Autor: Elisabeth Brambilla, Laurence Chaperot, Christian Brambilla, Olivier Micheau, Joel Plumas, Sylvie Gazzeri, Caroline Salon, Beatrice Eymin

Publikováno v: Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, 2006, 13 (2), pp.260-72. ⟨10.1038/sj.cdd.4401739⟩
Cell Death and Differentiation, Nature Publishing Group, 2006, 13 (2), pp.260-72. 〈10.1038/sj.cdd.4401739〉

E2F1 is a transcription factor that plays a well-documented role during S phase progression and apoptosis. We had previously postulated that the low level of E2F1 in primary lung adenocarcinoma contributes to their carcinogenesis. Here, we show that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362c92e058cf307028ee5328e7da8de4
https://pubmed.ncbi.nlm.nih.gov/16052233

Palmitoylation of TNF alpha is involved in the regulation of TNF receptor 1 signalling

Autor: Marie-Christine Alessi, Jean Michel Brunel, Roland Govers, Bernadette Bonardo, Imène Kara, Regina Fluhrer, Jean-François Landrier, Christian Haass, Marjorie Poggi, Franck Peiretti

Publikováno v: Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, 2013, 1833 (3), pp.602-612. ⟨10.1016/j.bbamcr.2012.11.009⟩
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2013, 1833 (3), pp.602-612. ⟨10.1016/j.bbamcr.2012.11.009⟩
BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2013, 1833 (3), pp.602-12
Biochimica et biophysica acta / Molecular cell research 1833(3), 602-612 (2013). doi:10.1016/j.bbamcr.2012.11.009

International audience; The pleiotropic pro-inflammatory cytokine tumour necrosis factor alpha (TNF) is synthesised as a transmembrane protein that is subject to palmitoylation. In this study, the roles of this acylation on TNF-mediated biological ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735f8c2776c78cf04cd352d92798c9cc
https://hal.inrae.fr/hal-02646290