Les canaux calciques Ca v 1.4 dans la physiopathologie du psoriasis

Autor: Pelletier, Lucette, Savignac, Magali

Publikováno v: médecine/sciences
médecine/sciences, 2022, 38 (8-9), pp.634-636. ⟨10.1051/medsci/2022091⟩

International audience; Le psoriasis est une maladie inflammatoire chronique de la peau, à forte charge émotionnelle, et qui affecte 2 à 3 % de la population mondiale. Elle est fréquemment associée à des comorbidités, comme l’arthrite ou les

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::86365d5793259d2958ade8375fd35926
https://ut3-toulouseinp.hal.science/hal-04009355

Calcium in the Backstage of Malaria Parasite Biology

Autor: Lucas Silva de Oliveira, Marcos Rodrigo Alborghetti, Renata Garcia Carneiro, Izabela Marques Dourado Bastos, Rogerio Amino, Philippe Grellier, Sébastien Charneau

Publikováno v: Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, 2021, 11, pp.708834. ⟨10.3389/fcimb.2021.708834⟩
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

The calcium ion (Ca2+) is a ubiquitous second messenger involved in key biological processes in prokaryotes and eukaryotes. In Plasmodium species, Ca2+ signaling plays a central role in the parasite life cycle. It has been associated with parasite de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec89bcb96e01890a4b1ccbed748f1405
https://doi.org/10.3389/fcimb.2021.708834

Calcium levels in the Golgi complex regulate clustering and apical sorting of GPI-APs in polarized epithelial cells

Autor: Julia von Blume, Maria Nitti, Stéphanie Lebreton, Dandan Liu, Chiara Zurzolo, Simona Paladino, Paolo Pinton

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (33), pp.e2014709118. ⟨10.1073/pnas.2014709118⟩
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (33), pp.e2014709118. ⟨10.1073/pnas.2014709118⟩
Proc Natl Acad Sci U S A

International audience; Glycosylphosphatidylinositol-anchored proteins (GPI-APs) are lipid-associated luminal secretory cargoes selectively sorted to the apical surface of the epithelia where they reside and play diverse vital functions. Cholesterol-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1cfa4878e77e0b1d36f0524f7f4ca2
https://hal-pasteur.archives-ouvertes.fr/pasteur-03517396

Structural and biochemical evidence for the emergence of a calcium-regulated actin cytoskeleton prior to eukaryogenesis

Autor: Caner Akıl, Linh T. Tran, Magali Orhant-Prioux, Yohendran Baskaran, Yosuke Senju, Shuichi Takeda, Phatcharin Chotchuang, Duangkamon Muengsaen, Albert Schulte, Edward Manser, Laurent Blanchoin, Robert C. Robinson

Publikováno v: Communications Biology
Communications Biology, 2022, 5 (1), pp.890. ⟨10.1038/s42003-022-03783-1⟩

Charting the emergence of eukaryotic traits is important for understanding the characteristics of organisms that contributed to eukaryogenesis. Asgard archaea and eukaryotes are the only organisms known to possess regulated actin cytoskeletons. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774cb7a80f1037ad08a0f1c24b7dfc50
https://ousar.lib.okayama-u.ac.jp/63891

Efficacy and safety of calcium, magnesium, potassium, and sodium oxybates (lower-sodium oxybate [LXB]; JZP-258) in a placebo-controlled, double-blind, randomized withdrawal study in adults with narcolepsy with cataplexy

Autor: Rafael Del Rio Villegas, Karel Sonka, Roman Skowronski, Yves Dauvilliers, Markku Partinen, Lihua Tang, Michael J. Thorpy, Nancy Foldvary-Schaefer, Richard K. Bogan, Franck Skobieranda

Publikováno v: Sleep
SLEEP
SLEEP, American Academy of Sleep Medicine, 2021, 44 (3), ⟨10.1093/sleep/zsaa206⟩
SLEEP, Oxford University Press 2021, 44 (3), pp.zsaa206. ⟨10.1093/sleep/zsaa206⟩

Study Objectives Evaluate efficacy and safety of lower-sodium oxybate (LXB), a novel oxybate medication with 92% less sodium than sodium oxybate (SXB). Methods Adults aged 18–70 years with narcolepsy with cataplexy were eligible. The study included

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec60561b22e079fc899358eadf1e411
http://europepmc.org/articles/PMC7953213