Výsledky vyhledávání - "MESH : Bacterial Proteins/metabolism"

Dissecting the structural and chemical determinants of the 'open-to-closed' motion in the mannosyltransferase PimA from Mycobacteria

Autor: Natalia Comino, Alexandre Chenal, Beatriz Trastoy, Montse Tersa, Itxaso Anso, Lena Mäler, David Albesa-Jové, David Giganti, Ane Rodrigo-Unzueta, Jobst Liebau, Cecilia D’Angelo, Saioa Urresti, Mattia Ghirardello, J. Ignacio Delso, Javier O. Cifuente, Pedro Merino, Alberto Marina, Marcelo E. Guerin

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Biochemistry
Biochemistry, 2020, 59 (32), pp.2934-2945. ⟨10.1021/acs.biochem.0c00376⟩
Biochemistry, American Chemical Society, 2020, 59 (32), pp.2934-2945. ⟨10.1021/acs.biochem.0c00376⟩
Zaguán. Repositorio Digital de la Universidad de Zaragoza

The phosphatidyl-myo-inositol mannosyltransferase A (PimA) is an essential peripheral membrane glycosyltransferase that initiates the biosynthetic pathway of phosphatidyl-myo-inositol mannosides (PIMs), key structural elements and virulence factors o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c988513a56fe950e468a525d3ea0f08a
https://ueaeprints.uea.ac.uk/id/eprint/85153/

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Multi-omics Approach Reveals How Yeast Extract Peptides Shape Streptococcus thermophilus Metabolism

Autor: Martin Bo Uhre Pedersen, Vincent Juillard, Alain Sourabié, Eloi Haudebourg, Véronique Monnet, Lucas Proust, Iris Besançon

Publikováno v: Applied and Environmental Microbiology
Applied and Environmental Microbiology, American Society for Microbiology, 2020, 86 (22), ⟨10.1128/AEM.01446-20⟩
Appl Environ Microbiol

Peptides present in growth media are essential for nitrogen nutrition and optimal growth of lactic acid bacteria. In addition, according to their amino acid composition, they can also directly or indirectly play regulatory roles and influence global

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398bc4aeda757a95b9855f11a2be86ba
https://hal.inrae.fr/hal-03342053

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Evolutionary Dissection of the Dot/Icm System Based on Comparative Genomics of 58 Legionella Species

Autor: Álvaro Chiner-Oms, Carmen Buchrieser, Laura Gomez-Valero, Iñaki Comas

Publikováno v: Genome Biology and Evolution
Genome Biology and Evolution, Society for Molecular Biology and Evolution, 2019, 11 (9), pp.2619-2632. ⟨10.1093/gbe/evz186⟩
Genome Biology and Evolution, 2019, 11 (9), pp.2619-2632. ⟨10.1093/gbe/evz186⟩
Digital.CSIC. Repositorio Institucional del CSIC
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14 páginas, 2 figuras, 2 tablas
The Dot/Icm type IVB secretion system of Legionella pneumophila is essential for its pathogenesis by delivering >300 effector proteins into the host cell. However, their precise secretion mechanism and which comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a5785201b2ac1a7e51bc5def221019
https://hal-pasteur.archives-ouvertes.fr/pasteur-02553745/document

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Physiological and evolutionary implications of tetrameric photosystem I in cyanobacteria

Autor: Jonathan Nguyen, Meng Li, Egbert J. Boekema, Barry D. Bruce, Dmitry A. Semchonok, Muriel Gugger, Julian P. Whitelegge, Nathalie Sassoon, Thomas A. Witt, Alexandra Calteau

Publikováno v: Nature Plants
Nature Plants, Nature Publishing Group, 2019, 5 (12), pp.1309-1319. ⟨10.1038/s41477-019-0566-x⟩
Nature Plants, 2019, 5 (12), pp.1309-1319. ⟨10.1038/s41477-019-0566-x⟩
Nature Plants, 5(12), 1309-1319. Nature Publishing Group

Photosystem I (PSI) were reported as trimeric complexes in most characterized cyanobacteria, yet monomers in plants and algae PSI. Recent reports on tetrameric PSI raised questions regarding its structural basis, physiological role, phylogenetic dist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c9d5936406a8aee24169a32b0f4228
https://pubmed.ncbi.nlm.nih.gov/31819227

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New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach

Autor: Roland Brosch, María Noel Alvarez, Mariana Piuri, Alessandro Cascioferro, Analía Lima, Rosario Durán, Paulo C. Carvalho, Estefanía Urdániz, María-Natalia Lisa, Ana Denicola, Marco Bellinzoni, Otto Pritsch, Federico Carrion, Magdalena Gil, Annemarie Wehenkel, Pedro M. Alzari, Carlos Batthyány, Bernardina Rivera, Jessica Rossello

Publikováno v: Journal of Proteomics
Journal of Proteomics, Elsevier, 2019, 192, pp.321-333. ⟨10.1016/j.jprot.2018.09.013⟩
Journal of Proteomics, 2019, 192, pp.321-333. ⟨10.1016/j.jprot.2018.09.013⟩

International audience; PknG from Mycobacterium tuberculosis is a multidomain Serine/Threonine protein kinase that regulates bacterial metabolism as well as the pathogen's ability to survive inside the host by still uncertain mechanisms. To uncover P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d6e591b08630f1c8a11067058c5008
https://hal-pasteur.archives-ouvertes.fr/pasteur-02046106

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Vibrio cholerae chromosome 2 copy number is controlled by the methylation-independent binding of its monomeric initiator to the chromosome 1 crtS site

Autor: Maria-Vittoria Mazzuoli, Marie-Eve Val, Florian Fournes, Francisco de Lemos Martins, Didier Mazel

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2018, 46 (19), pp.10145-10156. ⟨10.1093/nar/gky790⟩
Nucleic Acids Research, Oxford University Press, 2018, 46 (19), pp.10145-10156. ⟨10.1093/nar/gky790⟩

International audience; Bacteria contain a primary chromosome and, frequently , either essential secondary chromosomes or dispensable megaplasmids of plasmid origin. Incoming plasmids are often poorly adapted to their hosts and their stabilization re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7512d0739ff49b3f282e9969f7b52d2c
https://hal-pasteur.archives-ouvertes.fr/pasteur-02890948/document

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Structural insights into the signalling mechanisms of two-component systems

Autor: Françoise Jacob-Dubuisson, Ariel E. Mechaly, Jean-Michel Betton, Rudy Antoine

Publikováno v: Nature Reviews Microbiology
Nature Reviews Microbiology, Nature Publishing Group, 2018, 16 (10), pp.585-593. ⟨10.1038/s41579-018-0055-7⟩
Nature Reviews Microbiology, 2018, 16 (10), pp.585-593. ⟨10.1038/s41579-018-0055-7⟩

International audience; Two-component systems reprogramme diverse aspects of microbial physiology in response to environmental cues. Canonical systems are composed of a transmembrane sensor histidine kinase and its cognate response regulator. They ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d20865488b33e00d14b96704a8cff2
https://hal.archives-ouvertes.fr/hal-02322157

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The Legionella pneumophila Methyltransferase RomA Methylates Also Non-histone Proteins during Infection

Autor: Srikanth Kudithipudi, Alexander Bröhm, Monica Rolando, Carmen Buchrieser, Sara Weirich, Albert Jeltsch, Maren Kirstin Schuhmacher

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, 2018, 430 (13), pp.1912-1925. ⟨10.1016/j.jmb.2018.04.032⟩
Journal of Molecular Biology, Elsevier, 2018, 430 (13), pp.1912-1925. ⟨10.1016/j.jmb.2018.04.032⟩

International audience; RomA is a SET-domain containing protein lysine methyltransferase encoded by the Gram-negative bacterium Legionella pneumophila. It is exported into human host cells during infection and has been previously shown to methylate h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2594e0ca3a9a8953e77d845282d55d
https://hal-pasteur.archives-ouvertes.fr/pasteur-02869016

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The pleiotropic Legionella transcription factor LvbR links the Lqs and c-di-GMP regulatory networks to control biofilm architecture and virulence

Autor: Laura Gomez-Valero, Hubert Hilbi, Ramon Hochstrasser, Tobias Sahr, Ursula Schell, Carmen Buchrieser, Aline Kessler, Sylvia Simon

Publikováno v: Environmental Microbiology
Environmental Microbiology, Society for Applied Microbiology and Wiley-Blackwell, 2019, Special Issue on Pathogen and drug resistance ecology, 21 (3), pp.1035-1053. ⟨10.1111/1462-2920.14523⟩
Environmental Microbiology, 2019, Special Issue on Pathogen and drug resistance ecology, 21 (3), pp.1035-1053. ⟨10.1111/1462-2920.14523⟩

The causative agent of Legionnaires' pneumonia, Legionella pneumophila, colonizes amoebae and biofilms in the environment. The opportunistic pathogen employs the Lqs (Legionella quorum sensing) system and the signaling molecule LAI-1 (Legionella auto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b3f81d592669d8a487826cb4f2fe86
https://pubmed.ncbi.nlm.nih.gov/30623561

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Coiled-Coil Antagonism Regulates Activity of Venus Flytrap-Domain-Containing Sensor Kinases of the BvgS Family

Autor: Lesne, Elodie, Dupré, Elian, Lensink, Marc, Locht, Camille, Antoine, Rudy, Jacob-Dubuisson, Françoise

Publikováno v: mBio
mBio, American Society for Microbiology, 2018, 9 (1), pp.e02052-17. ⟨10.1128/mBio.02052-17⟩
mBio, 2018, 9 (1), pp.e02052-17. ⟨10.1128/mBio.02052-17⟩
mBio, Vol 9, Iss 1 (2018)

Bordetella pertussis controls the expression of its virulence regulon through the two-component system BvgAS. BvgS is a prototype for a family of multidomain sensor kinases. In BvgS, helical linkers connect periplasmic Venus flytrap (VFT) perception

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7a7fef29cdab754a1ceb90daa87258ec
https://pubmed.ncbi.nlm.nih.gov/29487240

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