Výsledky vyhledávání - "MESH : B-Lymphocyte Subsets"

Somatic diversification in the absence of antigen-driven responses is the hallmark of the IgM+IgD+CD27+ B cell repertoire in infants

Autor: Maria Mamani-Matsuda, Frédéric Gauthier, Claude-Agnès Reynaud, Corinne Cordier, Capucine Picard, Damiana Lecoeuche, Jean-Claude Weill, Sandra K. Weller

Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2008, 205 (6), pp.1331-42. ⟨10.1084/jem.20071555⟩
The Journal of Experimental Medecine
The Journal of Experimental Medecine, The Rockefeller University Press, 2008, 205 (6), pp.1331-42. 〈10.1084/jem.20071555〉
Journal of Experimental Medicine, 2008, 205 (6), pp.1331-42. ⟨10.1084/jem.20071555⟩

International audience; T cell-dependent immune responses develop soon after birth, whereas it takes 2 yr for humans to develop T cell-independent responses. We used this dissociation to analyze the repertoire diversification of IgM(+)IgD(+)CD27(+) B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0931002431ee87e4ab64c257748949
http://europepmc.org/articles/PMC2413031

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Raised immunoglobulin A and circulating T follicular helper cells are linked to the development of food allergy in paediatric liver transplant patients

Autor: A. Minne, Bruno Detry, R. De Bruyne, Frédéric Gottrand, S. Van Biervliet, Philippe Gevaert, Charles Pilette, M. Van Winckel, N. De Ruyck, Bart N. Lambrecht, Melissa Dullaers, Delfien Bogaert, Françoise Smets, S. Vande Velde, Etienne Sokal, Jérémy Vanhelst

Publikováno v: CLINICAL AND EXPERIMENTAL ALLERGY
Clinical and Experimental Allergy
Clinical and Experimental Allergy, Wiley, 2015, Clinical and experimental allergy, 45, pp.1060-1070. ⟨10.1111/cea.12514⟩
Clinical and Experimental Allergy, 45(6), 1060. Wiley-Blackwell
Clinical and Experimental Allergy, 2015, Clinical and experimental allergy, 45, pp.1060-1070. ⟨10.1111/cea.12514⟩
Clinical & Experimental Allergy, 45(6), 1060-1070. Wiley-Blackwell Publishing Ltd

BACKGROUND: Post transplant food allergy (LTFA) is increasingly observed after pediatric liver transplantation (LT). Although the immunopathology of LTFA remains unclear, immunoglobulin (Ig) E seems to be implicated. OBJECTIVE: To study humoral and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fe9131ee795a3686c12e76d504d76d
http://hdl.handle.net/20.500.12210/5172

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B cells promote tumor progression in a mouse model of HPV-mediated cervical cancer

Autor: Alexandre, Tang, Gilles, Dadaglio, Marine, Oberkampf, Selene, Di Carlo, Lucie, Peduto, Daphné, Laubreton, Belinda, Desrues, Cheng-Ming, Sun, Xavier, Montagutelli, Claude, Leclerc

Publikováno v: International Journal of Cancer
International Journal of Cancer, Wiley, 2016, 139 (6), pp.1358-1371. ⟨10.1002/ijc.30169⟩
International Journal of Cancer, 2016, 139 (6), pp.1358-1371. ⟨10.1002/ijc.30169⟩

International audience; Enhancing anti-tumor immunity and preventing tumor escape are efficient strategies to increase the efficacy of therapeutic cancer vaccines. However, the treatment of advanced tumors remains difficult, mainly due to the immunos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f3e8d41901f511acea98c412557ed115
https://hal-pasteur.archives-ouvertes.fr/pasteur-01942430

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The effect of B-cell depletion therapy on serological evidence of B-cell and plasmablast activation in patients with rheumatoid arthritis over multiple cycles of rituximab treatment

Autor: Guy Serre, J. C. W. Edwards, H.C. Perry, I. de la Torre, Leonor Nogueira, M.C. Dickson, Maria J. Leandro, HM Parsons, Geraldine Cambridge

Publikováno v: Journal of Autoimmunity
Journal of Autoimmunity, Elsevier, 2014, 50, pp.67-76. ⟨10.1016/j.jaut.2013.12.002⟩

International audience; B-cell depletion therapy (BCDT) based on rituximab (RTX) induces clinical remission in a majority of seropositive patients with Rheumatoid arthritis (RA). However, all patients eventually relapse. The aim of this study was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62efc3c35bba328f68bef278cbb6ffe0
https://pubmed.ncbi.nlm.nih.gov/24365380

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Follicular lymphoma-like B cells in healthy individuals: a novel intermediate step in early lymphomagenesis

Autor: Claudine Schiff, Bertrand Montpellier, Julie Agopian, Bertrand Nadel, Michèle Milili, Sandrine Roulland, Pierre Grenot, Pascal Gauduchon, Jean Navarro, Pierre Lebailly

Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, 2006, 203 (11), pp.2425-31. ⟨10.1084/jem.20061292⟩
Journal of Experimental Medicine, Rockefeller University Press, 2006, 203 (11), pp.2425-31. ⟨10.1084/jem.20061292⟩

Follicular lymphoma (FL) is one of the most common B-cell lymphoma, and remains virtually incurable despite its relatively indolent nature. T(14;18)(q32;q21), the genetic hallmark and early initiating event of FL pathogenesis, is also present at low

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271f5336f7db5bc723ce2a800c0e2979
http://europepmc.org/articles/PMC2118129

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Immunoglobulin genes undergo legitimate repair in human B cells not only after cis- but also frequent trans-class switch recombination

Autor: Sylvia M. Bardet, Michel Cogné, Brice Laffleur, M Brousse, A Baylet, Armand Garot

Publikováno v: Genes and Immunity
Genes and Immunity, Nature Publishing Group: Open Access Hybrid Model Option B, 2014, 15 (5), pp.341-6. ⟨10.1038/gene.2014.25⟩

International audience; Immunoglobulin (Ig) genes specifically recruit activation-induced deaminase (AID) for 'on-target' DNA deamination, initiating either variable (V) region somatic hypermutation, or double-strand break intermediates of class swit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f7c8160d6a667d91df65432999dfab
https://hal.archives-ouvertes.fr/hal-01112042

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The Eμ enhancer region influences H chain expression and B cell fate without impacting IgVH repertoire and immune response in vivo

Autor: Marie Marquet, Claire Carrion, Pauline Rouaud, Sébastien Bender, Armand Garot, Sandrine Lecardeur, Yves Denizot, Michel Cogné, Eric Pinaud

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2014, 193 (3), pp.1171-83. ⟨10.4049/jimmunol.1302868⟩

The IgH intronic enhancer region Eμ is a combination of both a 220-bp core enhancer element and two 310–350-bp flanking scaffold/matrix attachment regions named MARsEμ. In the mouse, deletion of the core-enhancer Eμ element mainly affects VDJ re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4a398d25b4b24927afdee61f9540be
https://pubmed.ncbi.nlm.nih.gov/24965776

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Fibroblastic reticular cells guide T lymphocyte entry into and migration within the splenic T cell zone

Autor: Marc Bajénoff, Ronald N. Germain, Nicolas Glaichenhaus

Although a great deal is known about T cell entry into lymph nodes, much less is understood about how T lymphocytes access the splenic white pulp (WP). We show in this study that, as recently described for lymph nodes, fibroblastic reticular cells (F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9659527baa6a37bce8c5dbaa9bb9ba7b
https://hal.archives-ouvertes.fr/hal-00419277

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Human C3 deficiency associated with impairments in dendritic cell differentiation, memory B cells, and regulatory T cells

Autor: Arlette Tridon, Martine Pernollet, Josette Péguet-Navarro, Christian Drouet, Nicole Monnier, Marie-Bernadette Villiers, Denis Gerlier, Arije Ghannam, Joël Lunardi, Denise Ponard, Jean-Luc Fauquert

Publikováno v: Journal of Immunology
Journal of Immunology, 2008, 181 (7), pp.5158-66
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2008, 181 (7), pp.5158-66

Primary C3 deficiency, a rare autosomal inherited disease (OMIM 120700), was identified in a 2-year-old male suffering from recurrent pyogenic infections from early infancy with undetectable total complement hemolytic activity (CH50) and C3 values. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fd2c4cf17f8fe0b1d32b71e7be1916
https://www.hal.inserm.fr/inserm-00381929

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μ-Surrogate Light Chain Physicochemical Interactions of the Human PreB Cell Receptor: Implications for VH Repertoire Selection and Cell Signaling at the PreB Cell Stage

Autor: Gauthier, L, Lemmers, Bénédicte, Guelpa-Fonlupt, V, Fougereau, M, Schiff, C

The surrogate light chain (SL) composed of the λ-like and VpreB polypeptides is organized as two Ig domains and an extra-loop structure. It associates to the μ-chain in preB cells. We have produced human VpreB, SL, two Fdμ (VH-CH1), and the two co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbd29ee51f363eeff0116ad75af3895
https://doi.org/10.4049/jimmunol.162.1.41

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