Zobrazeno 1 - 10
of 11
pro vyhledávání: '"MESH : Antibody-Dependent Cell Cytotoxicity"'
Autor:
Jérémy Dufloo, Cyril Planchais, Stéphane Frémont, Valérie Lorin, Florence Guivel-Benhassine, Karl Stefic, Nicoletta Casartelli, Arnaud Echard, Philippe Roingeard, Hugo Mouquet, Olivier Schwartz, Timothée Bruel
Publikováno v:
Nature Communications
Nature Communications, 2022, 13 (1), pp.630. ⟨10.1038/s41467-022-28307-7⟩
Nature Communications, Nature Publishing Group, 2022, 13 (1), pp.630. ⟨10.1038/s41467-022-28307-7⟩
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Nature Communications, 2022, 13 (1), pp.630. ⟨10.1038/s41467-022-28307-7⟩
Nature Communications, Nature Publishing Group, 2022, 13 (1), pp.630. ⟨10.1038/s41467-022-28307-7⟩
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Broadly neutralizing antibodies (bNAbs) targeting the HIV-1 envelope glycoprotein (Env) are promising molecules for therapeutic or prophylactic interventions. Beyond neutralization, bNAbs exert Fc-dependent functions including antibody-dependent cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d00e57249593b1886353431589fbeb6
https://hal-pasteur.archives-ouvertes.fr/pasteur-03654220/file/s41467-022-28307-7.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03654220/file/s41467-022-28307-7.pdf
Autor:
Coënon, Loïs, Villalba, Martin
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2022, 13, pp.913215. ⟨10.3389/fimmu.2022.913215⟩
Frontiers in Immunology, Frontiers, 2022, 13, pp.913215. ⟨10.3389/fimmu.2022.913215⟩
International audience; Antibody-dependent cell-mediated cytotoxicity (ADCC) is a potent cytotoxic mechanism that is mainly mediated in humans by natural killer (NK) cells. ADCC mediates the clinical benefit of several widely used cytolytic monoclona
Autor:
James P. Di Santo, Pierre Bruhns, Laurence Fiette, Friederike Jönsson, David A. Mancardi, Clifford A. Lowell, Bruno Iannascoli, Marcello Albanesi
Publikováno v:
Blood
Blood, American Society of Hematology, 2013, 122 (18), pp.3160-3164. ⟨10.1182/blood-2013-04-497446⟩
Blood, 2013, 122 (18), pp.3160-3164. ⟨10.1182/blood-2013-04-497446⟩
Blood, American Society of Hematology, 2013, 122 (18), pp.3160-3164. ⟨10.1182/blood-2013-04-497446⟩
Blood, 2013, 122 (18), pp.3160-3164. ⟨10.1182/blood-2013-04-497446⟩
International audience; Tumor engraftment followed by monoclonal antibody (mAb) therapy targeting tumor antigens represents a gold standard for assessing the efficiency of mAbs to eliminate tumor cells. Mouse models have demonstrated that receptors f
Autor:
Valentina Cecchinato, Jean-Michel Heraud, Gary Landucci, Stephen Whitney, Vibeke Andresen, Ruth H. Florese, Janos Nacsa, Izabela Bialuk, Thorsten Demberg, Marjorie Robert Guroff, Robyn Washington Parks, Donald N. Forthal, David Venzon, Shari N. Gordon, Genoveffa Franchini, Valerio W. Valeri, David C. Montefiori
Publikováno v:
Vaccine
Vaccine, Elsevier, 2011, 30 (1), pp.78-94. ⟨10.1016/j.vaccine.2011.10.040⟩
Vaccine, Elsevier, 2011, 30 (1), pp.78-94. ⟨10.1016/j.vaccine.2011.10.040⟩
International audience; The role of antibodies directed against the hyper variable envelope region V1 of human immunode-ficiency virus type 1 (HIV-1), has not been thoroughly studied. We show that a vaccine able to elicit strain-specific non-neutrali
Publikováno v:
Blood
Blood, American Society of Hematology, 2008, 111 (7), pp.3571-8. ⟨10.1182/blood-2007-07-100057⟩
Blood, 2008, 111 (7), pp.3571-8. ⟨10.1182/blood-2007-07-100057⟩
Blood, American Society of Hematology, 2008, 111 (7), pp.3571-8. ⟨10.1182/blood-2007-07-100057⟩
Blood, 2008, 111 (7), pp.3571-8. ⟨10.1182/blood-2007-07-100057⟩
NKG2D is a multisubunit activation receptor that allows natural killer (NK) cells to detect and eliminate stressed, infected, and transformed host cells. However, the chronic exposure of NK cells to cell-bound NKG2D ligands has been shown to impair N
Autor:
André Nicolas, Otto Pritsch, Sophie Viel, Sebastian Amigorena, Pablo Oppezzo, Adele Heitzmann, Xavier Sastre-Garau, Pascale Hubert, Eduardo Osinaga
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2011, 71 (15), pp.5134-43. ⟨10.1158/0008-5472.CAN-10-4222⟩
Cancer Research; Vol 71
Cancer Research, American Association for Cancer Research, 2011, 71 (15), pp.5134-43. 〈10.1158/0008-5472.CAN-10-4222〉
Cancer Research, American Association for Cancer Research, 2011, 71 (15), pp.5134-43. ⟨10.1158/0008-5472.CAN-10-4222⟩
Cancer Research; Vol 71
Cancer Research, American Association for Cancer Research, 2011, 71 (15), pp.5134-43. 〈10.1158/0008-5472.CAN-10-4222〉
Antibody-dependent cell cytotoxicity (ADCC) plays a critical role in monoclonal antibody (mAb)-mediated cancer therapy. ADCC, however, has not been directly shown in vivo but inferred from the requirement for IgG Fc receptors (FcγR) in tumor rejecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332f9cf0fa60a2116b3cc261a15b7592
https://hal-riip.archives-ouvertes.fr/pasteur-00685062
https://hal-riip.archives-ouvertes.fr/pasteur-00685062
Publikováno v:
Trends in Immunology
Trends in Immunology, Elsevier, 2011, 32 (11), pp.510-6. ⟨10.1016/j.it.2011.07.003⟩
Trends in Immunology, 2011, 32 (11), pp.510-6. ⟨10.1016/j.it.2011.07.003⟩
Trends in Immunology, Elsevier, 2011, 32 (11), pp.510-6. ⟨10.1016/j.it.2011.07.003⟩
Trends in Immunology, 2011, 32 (11), pp.510-6. ⟨10.1016/j.it.2011.07.003⟩
International audience; Monoclonal antibodies (mAbs) are in widespread use for the treatment of cancer. Their success as cancer therapeutics relies substantially on their ability to engage the immune system. Specifically, Fc-receptor-expressing immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd5a946a0145ff30d3d5fc503b59155
https://hal.archives-ouvertes.fr/hal-00744044
https://hal.archives-ouvertes.fr/hal-00744044
Publikováno v:
Clinical Reviews in Allergy and Immunology
Clinical Reviews in Allergy and Immunology, Humana Press, 2011, 40 (3), pp.151-8. ⟨10.1007/s12016-010-8204-4⟩
Clinical Reviews in Allergy and Immunology, Humana Press, 2011, 40 (3), pp.151-8. ⟨10.1007/s12016-010-8204-4⟩
International audience; Lupus nephritis (LN) remains the most common severe manifestation of systemic lupus erythematosus (SLE) characterized by the presence of autoantibodies (Abs) that are believed to play a central role in the pathogenesis of LN.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7dd5accff306654a306f7446dfd234b
https://hal.univ-brest.fr/hal-00771283
https://hal.univ-brest.fr/hal-00771283
Autor:
Josh Brody, Antonia M.S. Müller, Mark P. Chao, Holbrook E Kohrt, Thomas F. Tedder, Ash A. Alizadeh, Matthew J. Goldstein, Ronald Levy, Lieping Chen, Roch Houot, Kipp Weiskopf, Steven Coutre, Debra K. Czerwinski, Russell K. Pachynski
Publikováno v:
Blood
Blood, American Society of Hematology, 2011, 117 (8), pp.2423-32. ⟨10.1182/blood-2010-08-301945⟩
Blood, 2011, 117 (8), pp.2423-32. ⟨10.1182/blood-2010-08-301945⟩
Blood, American Society of Hematology, 2011, 117 (8), pp.2423-32. ⟨10.1182/blood-2010-08-301945⟩
Blood, 2011, 117 (8), pp.2423-32. ⟨10.1182/blood-2010-08-301945⟩
Antibody-dependent cell-mediated cytotoxicity (ADCC), which is largely mediated by natural killer (NK) cells, is thought to play an important role in the efficacy of rituximab, an anti-CD20 monoclonal antibody (mAb) used to treat patients with B-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd66d5151284293386fff7eb71778ba4
https://hal.archives-ouvertes.fr/hal-00743985
https://hal.archives-ouvertes.fr/hal-00743985
Autor:
Jacques-Olivier Pers, Séverine Loisel, Christian Berthou, Virginie Buhé, Rémi Marianowski, Pierre Youinou
Publikováno v:
Journal of Autoimmunity
Journal of Autoimmunity, Elsevier, 2010, 34 (2), pp.136-44
Journal of Autoimmunity, Elsevier, 2010, 34 (2), pp.136-44
International audience; As a model to dissect the effects of CpG-oligonucleotides (CpG) on rituximab (RTX)-mediated therapeutic killing of autoimmune or malignant B lymphocytes, nude mice were grafted with Daudi human B cells. These mice were then in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::637aa191428713aa19c96a756511f1e8
https://hal.univ-brest.fr/hal-01134385
https://hal.univ-brest.fr/hal-01134385