Do gene-environment interactions play a role in COVID-19 distribution? The case of Alpha-1 Antitrypsin, air pollution and COVID-19

Autor: Arturo Tozzi, Nicola Murgia, Angelo Corsico, Isabella Annesi-Maesano, Cara Nichole Maesano, Gennaro D'Amato

Publikováno v: Multidisciplinary Respiratory Medicine
Multidisciplinary Respiratory Medicine, 2021, 16 (1), pp.741. ⟨10.4081/mrm.2021.741⟩

International audience; Background: Gene-environment interactions are relevant for several respiratory diseases. This communication raises the hypothesis that the severity of COVID-19, a complex disease where the individual response to the infection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f603328096cef8f44e162868c91d25f
https://doi.org/10.4081/mrm.2021.741

Exposure to Atmospheric Ultrafine Particles Induces Severe Lung Inflammatory Response and Tissue Remodeling in Mice

Autor: Saleh, Yara, Antherieu, Sebastien, Dusautoir, Romain, Y. Alleman, Laurent, Sotty, Jules, De Sousa, Corentin, Platel, Anne, Perdrix, Esperanza, Riffault, Véronique, Fronval, Isabelle, Nesslany, Fabrice, Canivet, Ludivine, Garçon, Guillaume, Lo-Guidice, Jean-Marc

Publikováno v: International Journal of Environmental Research and Public Health, Vol 16, Iss 7, p 1210 (2019)
International Journal of Environmental Research and Public Health
Volume 16
Issue 7
International Journal of Environmental Research and Public Health, MDPI, 2019, 16 (7), pp.1210. ⟨10.3390/ijerph16071210⟩
International Journal of Environmental Research and Public Health, 2019, 16 (7), pp.1210. ⟨10.3390/ijerph16071210⟩

Exposure to particulate matter (PM) is leading to various respiratory health outcomes. Compared to coarse and fine particles, less is known about the effects of chronic exposure to ultrafine particles, despite their higher number and reactivity. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::26b5525c4e26cfd2eef62ef8e4562f6d
https://www.mdpi.com/1660-4601/16/7/1210

Does the oxidative stress play a role in the associations between outdoor air pollution and persistent asthma in adults? Findings from the EGEA study

Autor: Anaïs Havet, Bénédicte Jacquemin, Valérie Siroux, Raphaëlle Varraso, Nino Künzli, Nicole Le Moual, Bert Brunekreef, Margaux Sanchez, Rachel Nadif, Zhen Li, Régis Matran, Farid Zerimech

Publikováno v: Environmental Health
Environmental Health, 2019, 18 (1), pp.90. ⟨10.1186/s12940-019-0532-0⟩
Environmental Health, BioMed Central, 2019, 18 (1), pp.90. ⟨10.1186/s12940-019-0532-0⟩
Environmental Health, Vol 18, Iss 1, Pp 1-9 (2019)

BackgroundEvidences that oxidative stress plays a role in the associations between outdoor air pollution and asthma are growing. We aimed to study the role of plasma fluorescent oxidation products levels (FlOPs; an oxidative stress-related biomarker)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0755b57a58ff61a544568d08f06dad44
https://www.hal.inserm.fr/inserm-03156725/file/s12940-019-0532-0.pdf

Prenatal particulate air pollution and DNA methylation in newborns: an epigenome-wide meta-analysis

Autor: Tim S. Nawrot, Cheng Peng, Kelly M. Bakulski, Paul Yousefi, Mariona Bustamante, Lorenzo Richiardi, Josep M. Antó, Erik Melén, Göran Pershagen, Dawn L. DeMeo, Jason I. Feinberg, Cheng-Jian Xu, Gerard H. Koppelman, Carrie V. Breton, Inger Kull, Rosalind J. Wright, Akram Ghantous, Diane R. Gold, Charles Auffray, Michelle Plusquin, Nathanaël Lemonnier, Herman T. den Dekker, Johanna Lepeule, Itai Kloog, Christine Ladd-Acosta, Martine Vrijheid, Olena Gruzieva, Isabella Annesi-Maesano, Bert Brunekreef, Heather E. Volk, Janine F. Felix, José Luis Ruiz, Zdenko Herceg, Stephanie J. London, Allan C. Just, Cilla Söderhäll, Simon Kebede Merid, Lu Gao, Anna Bergström, Regina Grazuleviciene, Jean Bousquet, Vincent W. V. Jaddoe, Andrea A. Baccarelli, Liesbeth Duijts, Jordi Sunyer, Costanza Pizzi, Juha Kere, Caroline L Relton, Franca Rusconi, Manolis Kogevinas, Ulrike Gehring, Kristine B. Gutzkow, Paolo Vineis, Carles Hernandez-Ferrer

Publikováno v: Gruzieva, O, Xu, C-J, Yousefi, P, Relton, C, Merid, S K, Breton, C V, Gao, L, Volk, H E, Feinberg, J I, Ladd-Acosta, C, Bakulski, K, Auffray, C, Lemonnier, N, Plusquin, M, Ghantous, A, Herceg, Z, Nawrot, T S, Pizzi, C, Richiardi, L, Rusconi, F, Vineis, P, Kogevinas, M, Felix, J F, Duijts, L, den Dekker, H T, Jaddoe, V W V, Ruiz, J L, Bustamante, M, Antó, J M, Sunyer, J, Vrijheid, M, Gutzkow, K B, Grazuleviciene, R, Hernandez-Ferrer, C, Annesi-Maesano, I, Lepeule, J, Bousquet, J, Bergström, A, Kull, I, Söderhäll, C, Kere, J, BIOS Consortium, Gehring, U, Brunekreef, B, Just, A C, Wright, R J, Peng, C, Gold, D R, Kloog, I, DeMeo, D L & Pershagen, G 2019, ' Prenatal Particulate Air Pollution and DNA Methylation in Newborns : An Epigenome-Wide Meta-Analysis ', Environmental Health Perspectives, vol. 127, no. 5, 057012 . https://doi.org/10.1289/EHP4522
Environmental Health Perspectives
Environmental Health Perspectives, National Institute of Environmental Health Sciences, 2019, 127 (5), pp.057012. ⟨10.1289/EHP4522⟩
Environmental Health Perspectives, 127(5):057012. US DEPT HEALTH HUMAN SCIENCES PUBLIC HEALTH SCIENCE
Environmental Health Perspectives, 127(5):057012. Public Health Services, US Dept of Health and Human Services
Environmental Health Perspectives, 2019, 127 (5), pp.057012. ⟨10.1289/EHP4522⟩
Recercat. Dipósit de la Recerca de Catalunya
instname
Digital.CSIC. Repositorio Institucional del CSIC

Background: Prenatal exposure to air pollution has been associated with childhood respiratory disease and other adverse outcomes. Epigenetics is a suggested link between exposures and health outcomes. Objectives: We aimed to investigate associations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70cb2abd07214615fb55ce14d6a1e9a
http://hdl.handle.net/10230/42203

Effects of urban coarse particles inhalation on oxidative and inflammatory parameters in the mouse lung and colon

Autor: Laurent Y. Alleman, Adil Ouali Alami, Corinne Gower-Rousseau, Madjid Djouina, Pierre Desreumaux, Mathilde Body-Malapel, Esperanza Perdrix, Cécile Vignal, Muriel Pichavant, Florian Dingreville, Christophe Waxin

Publikováno v: Particle and Fibre Toxicology
Particle and Fibre Toxicology, 2017, 14 (1), pp.46. ⟨10.1186/s12989-017-0227-z⟩
Particle and Fibre Toxicology, BioMed Central, 2017, 14 (1), pp.46. ⟨10.1186/s12989-017-0227-z⟩
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-13 (2017)
ResearcherID

Background Air pollution is a recognized aggravating factor for pulmonary diseases and has notably deleterious effects on asthma, bronchitis and pneumonia. Recent studies suggest that air pollution may also cause adverse effects in the gastrointestin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cddbde5cbf6c8f82b6a47de4782979f
https://hal.science/hal-01935778/document