Výsledky vyhledávání - "MESH : Acetylcysteine"

Structure of human lysosomal acid α-glucosidase–a guide for the treatment of Pompe disease

Autor: Véronique Roig-Zamboni, Beatrice Cobucci-Ponzano, Roberta Iacono, Maria Carmina Ferrara, Stanley Germany, Yves Bourne, Giancarlo Parenti, Marco Moracci, Gerlind Sulzenbacher

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8, pp.1111. ⟨10.1038/s41467-017-01263-3⟩
'Nature Communications ', vol: 8, pages: 1111-1-1111-10 (2017)
Nature Communications, Nature Publishing Group, 2017, 8, pp.1111. 〈10.1038/s41467-017-01263-3〉
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications, Nature Publishing Group, 2017, ⟨10.1038/s41467-017-01263-3⟩
Nature communications 8 (2017). doi:10.1038/s41467-017-01263-3
info:cnr-pdr/source/autori:Roig-Zamboni V.; Cobucci-Ponzano B.; Iacono R.; Ferrara M.C.; Germany S.; Bourne Y.; Parenti G.; Moracci M.; Sulzenbacher G./titolo:Structure of human lysosomal acid alpha-glucosidase-A guide for the treatment of Pompe disease/doi:10.1038%2Fs41467-017-01263-3/rivista:Nature communications/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Nature Communications, 2017, ⟨10.1038/s41467-017-01263-3⟩
Nature Communications, 2017, 8, pp.1111. ⟨10.1038/s41467-017-01263-3⟩

Pompe disease, a rare lysosomal storage disease caused by deficiency of the lysosomal acid α-glucosidase (GAA), is characterized by glycogen accumulation, triggering severe secondary cellular damage and resulting in progressive motor handicap and pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c82ffd7ffc81e6e645698e18bb52b05
https://hal.archives-ouvertes.fr/hal-01802847/file/s41467-017-01263-3.pdf

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Effects of urban coarse particles inhalation on oxidative and inflammatory parameters in the mouse lung and colon

Autor: Laurent Y. Alleman, Adil Ouali Alami, Corinne Gower-Rousseau, Madjid Djouina, Pierre Desreumaux, Mathilde Body-Malapel, Esperanza Perdrix, Cécile Vignal, Muriel Pichavant, Florian Dingreville, Christophe Waxin

Publikováno v: Particle and Fibre Toxicology
Particle and Fibre Toxicology, 2017, 14 (1), pp.46. ⟨10.1186/s12989-017-0227-z⟩
Particle and Fibre Toxicology, BioMed Central, 2017, 14 (1), pp.46. ⟨10.1186/s12989-017-0227-z⟩
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-13 (2017)
ResearcherID

Background Air pollution is a recognized aggravating factor for pulmonary diseases and has notably deleterious effects on asthma, bronchitis and pneumonia. Recent studies suggest that air pollution may also cause adverse effects in the gastrointestin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cddbde5cbf6c8f82b6a47de4782979f
https://hal.science/hal-01935778/document

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Oxidized Low-Density Lipoproteins Trigger Endoplasmic Reticulum Stress in Vascular Cells

Autor: Sanson, Marie, Augé, Nathalie, Vindis, Cécile, Muller, Carole, Bando, Yoshio, Thiers, Jean-Claude, Marachet, Marie-Agnè, s, Žarković, Kamelija, Sawa, Yoshiki, Salvayre, Robert, Nè, gre-Salvayre, Anne

Publikováno v: Circulation Research
Circulation Research, 2009, 104 (3), pp.328-36. ⟨10.1161/CIRCRESAHA.108.183749⟩
Circulation Research, American Heart Association, 2009, 104 (3), pp.328-36. ⟨10.1161/CIRCRESAHA.108.183749⟩

Oxidized low-density lipoproteins (oxLDLs) trigger various biological responses potentially involved in atherogenesis. Disturbing endoplasmic reticulum (ER) function results in ER stress and unfolded protein response, which tends to restore ER homeos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd73aa192d4287182e7bd40c0593dbae
https://doi.org/10.1161/circresaha.108.183749

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Protein degradation, as with protein synthesis, is required during not only long-term spatial memory consolidation but also reconsolidation

Autor: Lionel Moulédous, Julien Artinian, Xavier De Jaeger, Pascal Roullet, Bernard Frances, Anne-Marie T. McGauran

Publikováno v: European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2008, 27 (11), pp.3009-19. ⟨10.1111/j.1460-9568.2008.06262.x⟩

The formation of long-term memory requires protein synthesis, particularly during initial memory consolidation. This process also seems to be dependant upon protein degradation, particularly degradation by the ubiquitin-proteasome system. The aim of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88e9029db37179575a0979a4c49c699
https://doi.org/10.1111/j.1460-9568.2008.06262.x

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Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting D-serine-dependent NMDA receptor activation

Autor: Haxaire, Coline, Turpin, Fabrice R, Potier, Brigitte, Kervern, Myriam, Sinet, Pierre-Marie, Barbanel, Gérard, Mothet, Jean-Pierre, Dutar, Patrick, Billard, Jean-Marie

Publikováno v: Aging Cell
Aging Cell, Wiley Open Access, 2012, 11 (2), pp.336-44. ⟨10.1111/j.1474-9726.2012.00792.x⟩
Aging Cell, 2012, 11 (2), pp.336-44. ⟨10.1111/j.1474-9726.2012.00792.x⟩
Aging Cell, Wiley Open Access, 2012, 11 (2), pp.336-44. 〈10.1111/j.1474-9726.2012.00792.x〉

International audience; Oxidative stress (OS) resulting from an imbalance between antioxidant defenses and the intracellular accumulation of reactive oxygen species (ROS) contributes to age-related memory deficits. While impaired synaptic plasticity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1df0a5c3613f45186b459b99035e1870
https://hal.archives-ouvertes.fr/hal-00720367

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CFTR Is Involved in the Fine Tuning of Intracellular Redox Status

Autor: Marc Cougnon, Nicolas Melis, Christophe Duranton, Baharia Mograbi, Isabelle Rubera, Abderrahman Chargui, Michel Tauc

Publikováno v: American Journal of Pathology
American Journal of Pathology, American Society for Investigative Pathology, 2012, 181 (4), pp.1367-1377. ⟨10.1016/j.ajpath.2012.06.017⟩

International audience; Adaptation to hypoxia is an essential physiological response to decrease in tissue oxygenation. This process is primarily under the control of transcriptional activator hypoxia-inducible factor (HIF1). A better understanding o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d08af3c77280c5f2d0cd3caa3fc7ae66
https://hal.archives-ouvertes.fr/hal-02466034

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Oxidative stress and successful antioxidant treatment in models of RYR1-related myopathy

Autor: James J. Dowling, S. Arbogast, John Y. Kuwada, Isabelle Marty, Susan V. Brooks, Joël Lunardi, Darcee D. Nelson, Ana Ferreiro, Junguk Hur, A. McEvoy, Trent Waugh

Publikováno v: Brain-A Journal of Neurology
Brain-A Journal of Neurology, 2012, 135 (Pt 4), pp.1115-27. ⟨10.1093/brain/aws036⟩
Brain-A Journal of Neurology, Oxford University Press (OUP), 2012, 135 (Pt 4), pp.1115-27. ⟨10.1093/brain/aws036⟩

International audience; The skeletal muscle ryanodine receptor is an essential component of the excitation-contraction coupling apparatus. Mutations in RYR1 are associated with several congenital myopathies (termed RYR1-related myopathies) that are t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a637d29fa4e973d79e44657df83a0d5a
https://pubmed.ncbi.nlm.nih.gov/22418739

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Differential antibacterial activity against Pseudomonas aeruginosa by carbon monoxide-releasing molecules

Autor: Mathieu, Desmard, Roberta, Foresti, Didier, Morin, Maylis, Dagouassat, Maylis, Dagoussat, Alain, Berdeaux, Erick, Denamur, Sian H, Crook, Brian E, Mann, David, Scapens, Philippe, Montravers, Jorge, Boczkowski, Roberto, Motterlini

Publikováno v: Antioxidants and Redox Signaling
Antioxidants and Redox Signaling, Mary Ann Liebert, 2012, 16 (2), pp.153-63. ⟨10.1089/ars.2011.3959⟩

International audience; AIMS: Carbon monoxide (CO) delivered in a controlled manner to cells and organisms mediates a variety of pharmacological effects to the extent that CO-releasing molecules (CO-RMs) are being developed for therapeutic purposes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0914ac4a0eee865a2ff277f06b292093
https://www.hal.inserm.fr/inserm-00656413/document

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Quantitative proteomic analysis of cyclosporine-induced toxicity in a human kidney cell line and comparison with tacrolimus

Autor: Elodie Mestre, Pierre Marquet, François-Ludovic Sauvage, Fabien Lamoureux, Marie Essig, Louis Noël Gastinel

Publikováno v: Journal of Proteomics
Journal of Proteomics, Elsevier, 2011, 75 (2), pp.677-94. ⟨10.1016/j.jprot.2011.09.005⟩

International audience; The calcineurin-inhibitors (CNIs) cyclosporine (CsA) and tacrolimus (TAC) remain the pillars of modern immunosuppression regimens used in solid organ transplantation. Nephrotoxicity is an adverse effect that limits their succe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583bed05aead43909de19afc5364c431
https://www.hal.inserm.fr/inserm-00925562

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