Výsledky vyhledávání - "MESH: ras-GRF1"

Polar gradients of the DYRK-family kinase Pom1 couple cell length with the cell cycle

Autor: Martine Berthelot-Grosjean, Sophie G. Martin

Publikováno v: Nature
Nature, Nature Publishing Group, 2009, 459 (7248), pp.852-6. ⟨10.1038/nature08054⟩

International audience; Cells normally grow to a certain size before they enter mitosis and divide. Entry into mitosis depends on the activity of Cdk1, which is inhibited by the Wee1 kinase and activated by the Cdc25 phosphatase. However, how cells s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e2f1da9988dc1c0d62b6c33bf422f6
https://doi.org/10.1038/nature08054

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The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors

Autor: Ben Hamida, Sami, Neasta, Jeremie, Lasek, Amy, Kharazia, Viktor, Zou, Mimi, Carnicella, Sebastien, Janak, Patricia, Ron, Dorit

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, 2012, 32 (45), pp.15849-58. ⟨10.1523/JNEUROSCI.2846-12.2012⟩

International audience; Uncontrolled consumption of alcohol is a hallmark of alcohol abuse disorders; however, the central molecular mechanisms underlying excessive alcohol consumption are still unclear. Here, we report that the GTP binding protein,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::d07976c08c134b8ce1a49cfcbeaa4f60
https://www.hal.inserm.fr/inserm-00802982

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The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors

Autor: Ben Hamida, Sami, Neasta, Jeremie, Lasek, Amy, Kharazia, Viktor, Zou, Mimi, Carnicella, Sebastien, Janak, Patricia, Ron, Dorit

Publikováno v: Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2012, 32 (45), pp.15849-58. ⟨10.1523/JNEUROSCI.2846-12.2012⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::d07976c08c134b8ce1a49cfcbeaa4f60
https://www.hal.inserm.fr/inserm-00802982

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The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors

Autor: Sami Ben Hamida, Sebastien Carnicella, Dorit Ron, Jérémie Neasta, Amy W. Lasek, Patricia H. Janak, Viktor Kharazia, Mimi Zou

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 32, iss 45
Journal of Neuroscience
Journal of Neuroscience, Society for Neuroscience, 2012, 32 (45), pp.15849-58. ⟨10.1523/JNEUROSCI.2846-12.2012⟩

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d31a2c83f621ddc54fce74538adf08
https://escholarship.org/uc/item/3j7230zp

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Ability of human CDC25B phosphatase splice variants to replace the function of the fission yeast Cdc25 cell cycle regulator

Autor: Bernard Ducommun, Odile Mondesert, Béatrix Bugler, Matthieu Lemaire

Publikováno v: FEMS Yeast Research
FEMS Yeast Research, Oxford University Press (OUP), 2004, 5 (3), pp.205-11. ⟨10.1016/j.femsyr.2004.07.003⟩

CDC25 phosphatases are essential and evolutionary-conserved actors of the eukaryotic cell cycle control. To examine and compare the properties of three splicing variants of human CDC25B, recombinant fission yeast strains expressing the human proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b558fdb1a9c59b837ad02c476788c6
https://hal.archives-ouvertes.fr/hal-00317426

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The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1

Autor: Roman Tyzio, Igor Medina, Yehezkel Ben-Ari, Christophe Pellegrino, Grigory Krapivinsky, Luba Krapivinsky, Anton Ivanov, Yunona Manasian, David E. Clapham

Publikováno v: Neuron
Neuron, Elsevier, 2003, 40 (4), pp.775-84

International audience; The NMDA subtype of glutamate receptors (NMDAR) at excitatory neuronal synapses plays a key role in synaptic plasticity. The extracellular signal-regulated kinase (ERK1,2 or ERK) pathway is an essential component of NMDAR sign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4696c48f91c6f460e95475a46fbc046f
https://pubmed.ncbi.nlm.nih.gov/14622581

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A fission yeast strain expressing human CDC25A phosphatase: a tool for selectivity studies of pharmacological inhibitors of CDC25

Autor: Marie Odile Galera-Contour, Matthieu Lemaire, Gregoire Prevost, Bernard Ducommun, Béatrix Bugler, Odile Mondesert, Marie-Christine Brezak

Publikováno v: Current Genetics
Current Genetics, Springer Verlag, 2004, 45 (5), pp.283-8. ⟨10.1007/s00294-003-0483-3⟩

Fission yeast is a simple eukaryotic model organism in which many aspects of cell cycle control can be explored. We examined by homologous recombination whether the human CDC25A phosphatase could substitute for the function of the fission yeast Cdc25

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44448fd8452426574f33c98af19c01d
https://pubmed.ncbi.nlm.nih.gov/14727060

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Characterization of membrane-localized and cytosolic Rac-GTPase-activating proteins in human neutrophil granulocytes: contribution to the regulation of NADPH oxidase

Autor: Gergely Molnár, Miklós Geiszt, Marie-Claire Dagher, Julien Fauré, Erzsébet Ligeti, Marie-Hélène Paclet, Françoise Morel, Andrea Havasi

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2001, 355 (Pt 3), pp.851-8
Biochemical Journal, 2001, 355 (Pt 3), pp.851-8
Europe PubMed Central
Scopus-Elsevier

International audience; We have investigated the intracellular localization and molecular identity of Rac-GTPase-activating proteins (Rac-GAPs) in human neutrophils. Immunoblot analysis detected the presence of both p190RhoGAP and Bcr mainly in the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83767d57ad2060d8cd184e29b6af535b
https://hal.science/hal-00820778

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The S / M checkpoint at 37°C and the recovery of viability of the mutant polδts3 require the crb2 + /rhp9 + gene in fission yeast

Autor: J. Tillit, Karine Piard, Muriel Grenon, Stefania Francesconi, Giuseppe Baldacci

Publikováno v: Molecular and General Genetics MGG
Molecular and General Genetics MGG, Springer Verlag, 1999, 260 (6), pp.522-534. ⟨10.1007/s004380050925⟩

International audience; We have isolated a mutant in fission yeast, in which mitosis is uncoupled from completion of DNA replication when DNA synthesis is impaired by a thermosensitive mutation in the gene encoding the catalytic subunit of DNA polyme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d982210794e877339b95539e6ecd7c4b
https://hal.archives-ouvertes.fr/hal-03008067

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