Zobrazeno 1 - 10
of 530
pro vyhledávání: '"MESH: peptide"'
Autor:
Karina T. Shirakawa, Fernanda Angélica Sala, Mayara M. Miyachiro, Viviana Job, Daniel Maragno Trindade, Andréa Dessen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (21), pp.e2219540120. ⟨10.1073/pnas.2219540120⟩
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (21), pp.e2219540120. ⟨10.1073/pnas.2219540120⟩
Peptidoglycan (PG) is a central component of the bacterial cell wall, and the disruption of its biosynthetic pathway has been a successful antibacterial strategy for decades. PG biosynthesis is initiated in the cytoplasm through sequential reactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1792c9045acdf80ae2e52e4fcc61ba
https://doi.org/10.1073/pnas.2219540120
https://doi.org/10.1073/pnas.2219540120
Autor:
Dukas Jurėnas, Martial Rey, Deborah Byrne, Julia Chamot-Rooke, Laurent Terradot, Eric Cascales
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2022, Methods in Molecular Biology, 50 (22), pp.13114-13127. ⟨10.1093/nar/gkac1162⟩
Nucleic Acids Research, 2022, Methods in Molecular Biology, 50 (22), pp.13114-13127. ⟨10.1093/nar/gkac1162⟩
Rearrangement hot spot (Rhs) proteins are members of the broad family of polymorphic toxins. Polymorphic toxins are modular proteins composed of an N-terminal region that specifies their mode of secretion into the medium or into the target cell, a ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c108f472fb36bcf7f27a279e0cc14b22
https://hal.science/hal-04009485/file/gkac1162.pdf
https://hal.science/hal-04009485/file/gkac1162.pdf
Fetal Programming by Methyl Donor Deficiency Produces Pathological Remodeling of the Ascending Aorta
Autor:
Sébastien Blaise, Jean-Louis Guéant, Jean-Michel Camadro, Sébastien Hergalant, Laetitia Vanalderwiert, Rosa-Maria Guéant-Rodriguez, Brittany Balint, Laurent Lignières
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2021, 41 (6), pp.1928-1941. ⟨10.1161/atvbaha.120.315587⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2021, 41 (6), pp.1928-1941. ⟨10.1161/ATVBAHA.120.315587⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2021, 41 (6), pp.1928-1941. ⟨10.1161/atvbaha.120.315587⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2021, 41 (6), pp.1928-1941. ⟨10.1161/ATVBAHA.120.315587⟩
Objective: Deficiency in vitamin B12/folate (methyl donor deficiency [MDD]) produces cardiovascular outcomes during aging and fetal programming effects in newborns of MDD mothers. Whether fetal programming provokes long-term effects on aorta remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b20e6604bfb390011bfd2b19b3e357
https://hal.archives-ouvertes.fr/hal-03238712
https://hal.archives-ouvertes.fr/hal-03238712
Autor:
Ryan W. Mull, Anthony Harrington, Shaynoor Dramsi, Yftah Tal-Gan, Laurence du Merle, Alexis Proutière
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
mBio
mBio, American Society for Microbiology, 2021, 12 (1), pp.e03189-20. ⟨10.1128/mBio.03189-20⟩
mBio, 2021, 12 (1), pp.e03189-20. ⟨10.1128/mBio.03189-20⟩
mBio
mBio, American Society for Microbiology, 2021, 12 (1), pp.e03189-20. ⟨10.1128/mBio.03189-20⟩
mBio, 2021, 12 (1), pp.e03189-20. ⟨10.1128/mBio.03189-20⟩
International audience; Streptococcus gallolyticus subsp. gallolyticus is an emerging opportunistic pathogen responsible for septicemia and endocarditis in the elderly. Invasive infections by S. gallolyticus subsp. gallolyticus are strongly linked to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061f3af7b181b291fe30e55bbe77ae95
https://doi.org/10.1128/mbio.03189-20
https://doi.org/10.1128/mbio.03189-20
Autor:
Stephen J. Galli, Martin L. Watzenboeck, Nicolas Gaudenzio, Thomas Marichal, Sylvia Knapp, Philipp Starkl, Frédéric Fontaine, Mindy Tsai, Riccardo Sibilano, Laurent L. Reber, André C. Mueller
Publikováno v:
Allergy
Allergy, 2022, 77 (2), pp.499-512. ⟨10.1111/all.14852⟩
Allergy, 2022, 77 (2), pp.499-512. ⟨10.1111/all.14852⟩
International audience; Background: In contrast to their clearly defined roles in allergic diseases, the physiologic functions of Immunoglobulin E antibodies (IgEs) and mast cells (MCs) remain enigmatic. Recent research supports the toxin hypothesis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1364330c2a92ede4bcc5ec0bcdfbc19
https://pubmed.ncbi.nlm.nih.gov/33840121
https://pubmed.ncbi.nlm.nih.gov/33840121
Autor:
Frédérique Moyrand, Prashanthi Natarajan, Guilhem Janbon, Jade Sales-Lee, Laura R. Tuck, Frank Feuerbach, Wallace Ewj, Luciana de Oliveira, Hiten D. Madhani, Corinne Maufrais
Publikováno v:
Wallace, E W J, Maufrais, C, Sales Lee, J, Tuck, L, de Oliveira, L, Feuerbach, F, Moyrand, F, Natarajan, P, Madhani, H D & Janbon, G 2020, ' Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom ', Nucleic Acids Research, vol. 48, no. 5, pp. 2312-2331 . https://doi.org/10.1093/nar/gkaa060
Nucleic Acids Research
Nucleic Acids Research, 2020, 48 (5), pp.2312-2331. ⟨10.1093/nar/gkaa060⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (5), pp.2312-2331. ⟨10.1093/nar/gkaa060⟩
Nucleic Acids Research
Nucleic Acids Research, 2020, 48 (5), pp.2312-2331. ⟨10.1093/nar/gkaa060⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (5), pp.2312-2331. ⟨10.1093/nar/gkaa060⟩
Eukaryotic protein synthesis generally initiates at a start codon defined by an AUG and its surrounding Kozak sequence context, but the quantitative importance of this context in different species is unclear. We tested this concept in two pathogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf61a7e41b710769c98f2c49ddc7d2bf
https://www.pure.ed.ac.uk/ws/files/133847580/gkaa060.pdf
https://www.pure.ed.ac.uk/ws/files/133847580/gkaa060.pdf
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis
Journal of Pharmaceutical and Biomedical Analysis, Elsevier, 2018, 150, pp.386-395. ⟨10.1016/j.jpba.2017.12.012⟩
Journal of Pharmaceutical and Biomedical Analysis, 2018, 150, pp.386-395. ⟨10.1016/j.jpba.2017.12.012⟩
Journal of Pharmaceutical and Biomedical Analysis, Elsevier, 2018, 150, pp.386-395. ⟨10.1016/j.jpba.2017.12.012⟩
Journal of Pharmaceutical and Biomedical Analysis, 2018, 150, pp.386-395. ⟨10.1016/j.jpba.2017.12.012⟩
International audience; Infliximab is a monoclonal antibody widely used for the treatment of inflammatory diseases. Over the past few years, many studies have assessed that monoclonal antibodies are prone to aggregation under stress conditions. The a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f824f3ebbc17e7500537683fa7e516ca
https://doi.org/10.1016/j.jpba.2017.12.012
https://doi.org/10.1016/j.jpba.2017.12.012
Autor:
Mzoughi, Olfa, Teixido, Meritxell, Planès, Rémi, Serrero, Manutea, Hamimed, Ibtissem, Zurita, Esther, Moreno, Miguel, Granados, Giovana, Lakhdar-Ghazal, Faouzi, BenMohamed, Lbachir, Giralt, Ernest, Bahraoui, Elmostafa
Publikováno v:
Bioscience Reports
Bioscience Reports, 2019, 39 (9), pp.1-15. ⟨10.1042/BSR20192196⟩
Bioscience reports, vol 39, iss 9
Bioscience Reports, 2019, 39 (9), pp.1-15. ⟨10.1042/BSR20192196⟩
Bioscience reports, vol 39, iss 9
International audience; The trimeric heptad repeat domains HR1 and HR2 of the human immunodeficiency virus 1 (HIV-1) gp41 play a key role in HIV-1-entry by membrane fusion. To develop efficient inhibitors against this step, the corresponding trimeric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d6dfc3e3783a50d8ce5ed458ed29d60e
https://doi.org/10.1042/BSR20192196
https://doi.org/10.1042/BSR20192196
Autor:
Brigitte Blumen, François Penin, Matthieu Fritz, Annette Martin, Célia Boukadida, Marie-Laure Fogeron
Publikováno v:
PLoS Pathogens
PLoS Pathogens, 2018, 14 (2), pp.e1006863. ⟨10.1371/journal.ppat.1006863⟩
PLoS Pathogens, Vol 14, Iss 2, p e1006863 (2018)
PLoS Pathogens, Public Library of Science, 2018, 14 (2), pp.e1006863. ⟨10.1371/journal.ppat.1006863⟩
PLoS Pathogens, 2018, 14 (2), pp.e1006863. ⟨10.1371/journal.ppat.1006863⟩
PLoS Pathogens, Vol 14, Iss 2, p e1006863 (2018)
PLoS Pathogens, Public Library of Science, 2018, 14 (2), pp.e1006863. ⟨10.1371/journal.ppat.1006863⟩
Over the recent years, several homologues with varying degrees of genetic relatedness to hepatitis C virus (HCV) have been identified in a wide range of mammalian species. HCV infectious life cycle relies on a first critical proteolytic event of its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96679972c4e7957811b757405d37d3a0
https://hal-pasteur.archives-ouvertes.fr/pasteur-02896778
https://hal-pasteur.archives-ouvertes.fr/pasteur-02896778
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (23), pp.9838-9859. ⟨10.1021/acs.jmedchem.7b01525⟩
Journal of Medicinal Chemistry, American Chemical Society, 2017, 60 (23), pp.9838-9859. ⟨10.1021/acs.jmedchem.7b01525⟩
International audience; Benzotriazepin-2-ones were designed to mimic the suggested bioactive γ-turn conformation of the Bip-Lys-Tyr tripeptide in Urocontrin ([Bip4]URP), which modulates the urotensin II receptor (UT) and differentiates the effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3747a23cc16304969b5e6c1bf7a12c5
https://doi.org/10.1021/acs.jmedchem.7b01525
https://doi.org/10.1021/acs.jmedchem.7b01525