Zobrazeno 1 - 10
of 59
pro vyhledávání: '"MESH: p38 Mitogen-Activated Protein Kinases"'
Autor:
Yiming Cai, Maya Modak, Sebastian Weigang, Emmie de Wit, Jean K. Lim, Alistair Dunham, Benjamin J. Polacco, Qiongyu Li, Svenja Ulferts, Gwendolyn M. Jang, Aurelien Dugourd, David E. Gordon, Jeffrey Z. Guo, Kirsten Obernier, Sophia Bouhaddou, Elizabeth R. Fischer, Anna Gaulton, Jason C.J. Chang, Bjoern Meyer, Diego Quintero, Julian Knerr, Trupti Patil, Emma J. Manners, Michael C. O’Neal, Monita Muralidharan, Joseph Hiatt, Ajda Rojc, James E. Melnyk, Tanja Kortemme, Benjamin R. tenOever, Thomas Vallet, Rémy Robinot, Cassandra Koh, Benjamin E. Nilsson-Payant, Ruth Hüttenhain, Saker Klippsten, Alicia L. Richards, Eloy Felix, Brian K. Shoichet, Beril Tutuncuoglu, Danielle L. Swaney, Veronica V. Rezelj, Jeffery R. Johnson, Margaret Soucheray, Marisa Goff, R. Dyche Mullins, Kris M. White, Erica Stevenson, Jyoti Batra, Christopher J.P. Mathy, Yuan Zhou, Minkyu Kim, Marco Vignuzzi, Claudia Hernandez-Armenta, Kevan M. Shokat, Julio Saez-Rodriguez, Jacqueline M. Fabius, Timothy McBride, Adolfo García-Sastre, Quang Dinh Tran, Alexandra Hardy, Elena Moreno, Alberto Valdeolivas, Mehdi Bouhaddou, Andrew R. Leach, Melanie Ott, Georg Kochs, Pedro Beltrao, Jiewei Xu, Robyn M. Kaake, Merve Cakir, Ying Shi, Nevan J. Krogan, Lisa Miorin, Danish Memon, David J. Broadhurst, Miguel Correa Marrero, Robert Grosse
Publikováno v:
Cell
Cell, vol 182, iss 3
Cell, Elsevier, 2020, 182, pp.685-712.e19. ⟨10.1016/j.cell.2020.06.034⟩
Cell, 2020, 182 (3), pp.685-712.e19. ⟨10.1016/j.cell.2020.06.034⟩
Cell, vol 182, iss 3
Cell, Elsevier, 2020, 182, pp.685-712.e19. ⟨10.1016/j.cell.2020.06.034⟩
Cell, 2020, 182 (3), pp.685-712.e19. ⟨10.1016/j.cell.2020.06.034⟩
Summary The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed hundreds of thousands of people worldwide, highlighting an urgent need to
Autor:
Marek Kovar, Jiri Masin, Peter Sebo, Irena Adkins, Martina Svedova, Ludmila Tučková, Marina A. Freudenberg, Jakub Tomala, Radovan Fišer, Gilles Dadaglio, Ondrej Cerny
Publikováno v:
Immunology and Cell Biology
Immunology and Cell Biology, Nature Publishing Group, 2016, 94 (4), pp.322-333. ⟨10.1038/icb.2015.87⟩
Immunology and Cell Biology, 2016, 94 (4), pp.322-333. ⟨10.1038/icb.2015.87⟩
Immunology and Cell Biology, Nature Publishing Group, 2016, 94 (4), pp.322-333. ⟨10.1038/icb.2015.87⟩
Immunology and Cell Biology, 2016, 94 (4), pp.322-333. ⟨10.1038/icb.2015.87⟩
International audience; The adenylate cyclase toxin-hemolysin (CyaA) of Bordetella pertussis is a bi-functional leukotoxin. It penetrates myeloid phagocytes expressing the complement receptor 3 and delivers into their cytosol its N-terminal adenylate
Autor:
Retailleau, Kevin, Toutain, Bertrand, Galmiche, Guillaume, Fassot, Celine, Sharif-Naeini, Reza, Kauffenstein, Gilles, Mericskay, Mathias, Duprat, Fabrice, Li, Linda, Mérot, Jean, Lardeux, Aurelie, Pizard, Anne, Baudrie, Véronique, Jeunemaitre, Xavier, Feil, Robert, Göthert, Joachim, Lacolley, Patrick, Henrion, Daniel, Li, Zhenlin, Loufrani, Laurent, Grimaud, L.
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2013, 33 (2), pp.339-346. ⟨10.1161/ATVBAHA.112.300708⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2013, 33 (2), pp.339-346. 〈10.1161/ATVBAHA.112.300708〉
Arteriosclerosis, Thrombosis, and Vascular Biology, 2013, 33 (2), pp.339-346. ⟨10.1161/ATVBAHA.112.300708⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2013, 33 (2), pp.339-346. ⟨10.1161/ATVBAHA.112.300708⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2013, 33 (2), pp.339-346. 〈10.1161/ATVBAHA.112.300708〉
Arteriosclerosis, Thrombosis, and Vascular Biology, 2013, 33 (2), pp.339-346. ⟨10.1161/ATVBAHA.112.300708⟩
Objective— In resistance arteries, diameter adjustment in response to pressure changes depends on the vascular cytoskeleton integrity. Serum response factor (SRF) is a dispensable transcription factor for cellular growth, but its role remains unkno
Autor:
Jérémy Brunet, Erwan Pernet, Lhousseine Touqui, Laurent Guillemot, Michel Chignard, Yongzheng Wu
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 194 (11), pp.5312-5319. ⟨10.4049/jimmunol.1402665⟩
Journal of Immunology, 2015, 194 (11), pp.5312-5319. ⟨10.4049/jimmunol.1402665⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2015, 194 (11), pp.5312-5319. ⟨10.4049/jimmunol.1402665⟩
Journal of Immunology, 2015, 194 (11), pp.5312-5319. ⟨10.4049/jimmunol.1402665⟩
Staphylococcus aureus is a common cause of bacterial infections in respiratory diseases. It secretes molecules to dampen host immunity, and the recently identified adenosine is one of these molecules. The type IIA secretory phospholipase A2 (sPLA2-II
Autor:
Laurent Guillemot, Lhousseine Touqui, Erwan Pernet, Dominique Leduc, Michel Chignard, Yongzheng Wu, Mathieu Medina
Publikováno v:
Biochimie
Biochimie, Elsevier, 2014, 107, pp.95-104. ⟨10.1016/j.biochi.2014.08.018⟩
Biochimie, 2014, 107, pp.95-104. ⟨10.1016/j.biochi.2014.08.018⟩
Biochimie, Elsevier, 2014, 107, pp.95-104. ⟨10.1016/j.biochi.2014.08.018⟩
Biochimie, 2014, 107, pp.95-104. ⟨10.1016/j.biochi.2014.08.018⟩
International audience; Pseudomonas aeruginosa pulmonary infection is a leading cause of death in numerous diseases such as cystic fibrosis (CF). The host cytosolic phospholipase A2α (cPLA2α) releases lipid mediators that play an important role in
Autor:
Vincent Denis, Christel Larbouret, Laetitia K. Linares, Esther Pérez-Gracia, Delphine Desigaud, Adeline Ayrolles-Torro, Nadia Vie, M. del Rio, Marta Jarlier, Clara Montagut, Diego Tosi, E W-F Lam, Laetitia Marzi, Mar Iglesias, Céline Gongora, Pierre Martineau, Eve Combes
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2016, 115 (10), pp.1223-1233. ⟨10.1038/bjc.2016.313⟩
British Journal of Cancer, Cancer Research UK, 2016, 115 (10), pp.1223-1233. ⟨10.1038/bjc.2016.313⟩
BACKGROUND: Cetuximab, a monoclonal antibody against EGFR used for the treatment of colorectal cancer (CRC), is ineffective in many patients. The aim of this study was to identify the signalling pathways activated by cetuximab in CRC cells and define
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4579077d1c4aa1c4faf7dd0c8990a4d2
https://www.hal.inserm.fr/inserm-02465222
https://www.hal.inserm.fr/inserm-02465222
Autor:
Hamadi Fetoui, Yassine Chtourou, Amel Laajimi, Abderraouf Kenani, Sonia Aroui, Annie-Claire Meunier, Feten Najlaoui
Publikováno v:
Tumor Biology
Tumor Biology, Springer Verlag, 2016, 37 (3), pp.3831-9. ⟨10.1007/s13277-015-4230-4⟩
Tumor Biology, Springer Verlag, 2016, 37 (3), pp.3831-9. ⟨10.1007/s13277-015-4230-4⟩
International audience; Gliomas are the most common and malignant primary brain tumors. They are associated with a poor prognosis despite the availability of multiple therapeutic options. Naringin, a common dietary flavonoid abundantly present in fru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8649d8b8a75f172d7f66f365ff1257
https://hal-riip.archives-ouvertes.fr/pasteur-01374978
https://hal-riip.archives-ouvertes.fr/pasteur-01374978
Autor:
Carole Couillault, Jonathan J. Ewbank, Nathalie Pujol, C. Léopold Kurz, Matthieu Pophillat, Sophie Cypowyj, Katja Ziegler
Publikováno v:
Cell Host and Microbe
Cell Host and Microbe, Elsevier, 2009, 5 (4), pp.341-52. ⟨10.1016/j.chom.2009.03.006⟩
Cell Host and Microbe, 2009, 5 (4), pp.341-52. ⟨10.1016/j.chom.2009.03.006⟩
Cell Host and Microbe, Elsevier, 2009, 5 (4), pp.341-52. ⟨10.1016/j.chom.2009.03.006⟩
Cell Host and Microbe, 2009, 5 (4), pp.341-52. ⟨10.1016/j.chom.2009.03.006⟩
International audience; Like other multicellular organisms, the model nematode C. elegans responds to infection by inducing the expression of defense genes. Among the genes upregulated in response to a natural fungal pathogen is nlp-29, encoding an a
Autor:
Jean-Marie Xuereb, Sanah Essayagh, Anne-Dominique Terrisse, Lise Tellier-Cirioni, Bernard Pipy, Pierre Sié
Publikováno v:
Thrombosis and Haemostasis
Thrombosis and Haemostasis, 2007, 98 (4), pp.831-7
Thrombosis and Haemostasis, 2007, 98 (4), pp.831-7
SummaryCirculating microparticles derived from different types of blood cells have been reported to impair endothelial function and to induce pro-inflammatory and prothrombotic endothelial phenotypes. Although the number of monocyte-derived micropart
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (37), pp.13777-82. ⟨10.1073/pnas.0605988103⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2006, 103 (37), pp.13777-82. ⟨10.1073/pnas.0605988103⟩
Previously we identified a transcription factor, LPS-Induced TNF-α Factor (LITAF), mediating inflammatory cytokine expression in LPS-induced processes. To characterize the role of LITAF in vivo , we generated a macrophage-specific LITAF-deficient mo