Visualizing the functional 3D shape and topography of long noncoding RNAs by single-particle atomic force microscopy and in-solution hydrodynamic techniques

Autor: Manikandan Karuppasamy, Paolo Annibale, Isabel Chillón, Tina Uroda, Jean-Marie Teulon, Marco Marcia, Jean-Luc Pellequer, Ombeline Pessey

Publikováno v: Nature Protocols
Nature Protocols, Nature Publishing Group, 2020, 15 (6), pp.2107-2139. ⟨10.1038/s41596-020-0323-7⟩
Nature Protocols, 2020, 15 (6), pp.2107-2139. ⟨10.1038/s41596-020-0323-7⟩

International audience; Long noncoding RNAs (lncRNAs) are recently discovered transcripts that regulate vital cellular processes, such as cellular differentiation and DNA replication, and are crucially connected to diseases. Although the 3D structure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f60008f0786b5cf33073a73554f99d46
https://pubmed.ncbi.nlm.nih.gov/32451442

Protonation of Lipids Impacts the Supramolecular and Biological Properties of Their Self-Assembly

Autor: Marie Breton, Nathalie Mignet, Martin Hof, Daniel Scherman, Jean-François Berret, Michel Bessodes, Chantal Pichon, Teresa Kral, Claudie Bourgaux

Publikováno v: Langmuir
Langmuir, American Chemical Society, 2011, 27 (20), pp.12336-45. 〈10.1021/la202439s〉
Langmuir, American Chemical Society, 2011, 27 (20), pp.12336-45. ⟨10.1021/la202439s⟩

International audience; We assessed in this work how a chemical structure difference could influence a supramolecular organization and then its biological properties. In our case study, we considered two amphiphilic lipidic gene vectors. The chemical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f560fa9ba17104626c065ce07544fe
https://doi.org/10.1021/la202439s

Receptor Displacement in the Cell Membrane by Hydrodynamic Force Amplification through Nanoparticles

Autor: Maximilian U. Richly, Antigoni Alexandrou, Jean-Marc Allain, Silvan Türkcan, Cédric Bouzigues

Publikováno v: Biophysical Journal
Biophysical Journal, Biophysical Society, 2013, 105 (1), pp.116-126. ⟨10.1016/j.bpj.2013.05.045⟩

International audience; We introduce an intrinsically multiplexed and easy to implement method to apply an external force to a biomolecule and thus probe its interaction with a second biomolecule or, more generally, its environment (for example, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b45b58b3bff48db7c2640bf689c8f4

Hydrodynamic characterization of recombinant human fibrinogen species

Autor: Jos Grimbergen, Susan T. Lord, Bertrand Raynal, Patrick England, Mattia Rocco, Aldo Profumo, Barbara Cardinali

Publikováno v: Thrombosis Research
Thrombosis Research, 2013, 132 (1), pp.e48-e53. ⟨10.1016/j.thromres.2013.04.005⟩

International audience; Introduction: Fibrinogen is a key component of the blood coagulation system and plays important, diverse roles in several relevant pathologies such as thrombosis, hemorrhage, and cancer. It is a large glycoprotein whose three-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4aa22a0c0ac957351ae876565ef764

Size-dependent nonlinear weak-field magnetic behavior of maghemite nanoparticles

Autor: Laurence Motte, Vincent Russier, Caroline de Montferrand, Dominique Bonnin, N. Lièvre, Marc Lecouvey, Yoann Lalatonne, Philippe Monod

Publikováno v: Small
Small, Wiley-VCH Verlag, 2012, 8 (12), pp.1945-56. ⟨10.1002/smll.201102660⟩

International audience; The magnetic behavior at room temperature of maghemite nanoparticles of variable sizes (from 7 to 20 nm) is compared using a conventional super quantum interference device (SQUID) and a recently patented technology, called MIA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54601946f26706c7beb6bb5268773817
https://pubmed.ncbi.nlm.nih.gov/22488765