Zobrazeno 1 - 10 of 43 pro vyhledávání: '"MESH: Wnt Proteins"'
1
Functional compensation precedes recovery of tissue mass following acute liver injury
Autor: Ira Fleming, Carolyn Winston, Benjamin Kruft, Alex K. Shalek, Wolfram Goessling, Satdarshan P.S. Monga, Florian Mueller, Sungjin Ko, Udayan Apte, Chad Walesky, Kellie E. Kolb, Jake Henderson
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.5785. ⟨10.1038/s41467-020-19558-3⟩
The liver plays a central role in metabolism, protein synthesis and detoxification. It possesses unique regenerative capacity upon injury. While many factors regulating cellular proliferation during liver repair have been identified, the mechanisms b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b098b526816baaea3f6aa2942d407e5
https://doaj.org/article/19ae1c964a6645e69ee2804af9f1cfd1
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2
ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling
Autor: Silvia Corrochano, Abigail Harris, Hans Clevers, Caroline Eozenou, Isabelle Stévant, Joelle Bignon-Topalovic, Nick Warr, Neila Belguith, Sara Wells, Bochra Ben Rhouma, Pam Siggers, Serge Nef, Daniel T. Grimes, Ken McElreavey, Rebecca D. Burdine, Feng Cong, Makoto Suzuki, Andy Greenfield, Danielle Sagar, Anu Bashamboo, Bon-Kyoung Koo, Raja Brauner
Publikováno v: Proceedings of the National Academy of Sciences, Vol. 115, No 21 (2018) pp. 5474-5479
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (21), pp.5474-5479. ⟨10.1073/pnas.1801223115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (21), pp.5474-5479. ⟨10.1073/pnas.1801223115⟩
Proceedings of the National Academy of Sciences of the United States of America, 115(21), 5474
Proceedings of the National Academy of Sciences of the United States of America, 115(21), 5474-5479. National Academy of Sciences
International audience; Mammalian sex determination is controlled by the antagonistic interactions of two genetic pathways: The SRY-SOX9-FGF9 network promotes testis determination partly by opposing proovarian pathways, while RSPO1/WNT-β-catenin/FOX
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f785b7c346bbb98027161ca7382405e7
https://hdl.handle.net/20.500.11755/a85a814a-a5a7-4064-9ca8-516f15a8bb58
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3
Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS
Autor: Phillip C. Wong, Diana Wiesner, Francesco Roselli, Tobias M. Boeckers, Deniz Yilmazer-Hanke, Barbara Commisso, Linyun Tang, Albert C. Ludolph, Jochen H. Weishaupt, Najwa Ouali Alami, Luc Dupuis, David Bayer, Bernd Baumann, Thomas Wirth
Publikováno v: Life science alliance 3(11), e201900571 (2020). doi:10.26508/lsa.201900571
Life Science Alliance
Life Science Alliance, Life Science Alliance LLC, 2020, 3 (11), pp.e201900571. ⟨10.26508/lsa.201900571⟩
Life Science Alliance, 2020, 3 (11), pp.e201900571. ⟨10.26508/lsa.201900571⟩
Chemogenetic motoneuron excitation and astrocyte GPCR-Gi signaling restore blood–spinal cord barrier, disrupted in four ALS mouse models, revealing its role in disease progression but not initiation.
Blood–spinal cord barrier (BSCB) disrupti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93218dfe1100975b7bc1fb24ea761df4
https://pub.dzne.de/record/164314
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4
The Wnt/Ca 2+ pathway is involved in interneuronal communication mediated by tunneling nanotubes
Autor: Gonzalo Córdova, Jessica Y Vargas, Frida Loria, Chiara Zurzolo, Masato Hasegawa, Geeske M. van Woerden, Yuan-Ju Wu, Sebastien Bellow, Takashi Nonaka, Capucine Trollet, Sylvie Syan
Publikováno v: EMBO Journal
EMBO Journal, EMBO Press, 2019, 38 (23), ⟨10.15252/embj.2018101230⟩
The EMBO Journal
EMBO Journal, 2019, 38 (23), ⟨10.15252/embj.2018101230⟩
EMBO Journal, 38(23):e101230. Wiley-Blackwell
International audience; Tunneling nanotubes (TNTs) are actin-based transient tubular connections that allow direct communication between distant cells. TNTs play an important role in several physiological (development, immunity, and tissue regenerati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbbd2a02d2def634543095dbd72de06
https://doi.org/10.15252/embj.2018101230
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5
Dental and extra-oral clinical features in 41 patients with WNT10A gene mutations
Autor: Tardieu, C., Jung, S., Niederreither, K., Prasad, M., Hadj-Rabia, S., Philip, N., Mallet, A., Consolino, E., Sfeir, E., Noueiri, B., Chassaing, Nicolas, Dollfus, H., Manière, M.C., Bloch-Zupan, A., Clauss, F.
Publikováno v: Clinical Genetics
Clinical Genetics, Wiley, 2017, 92 (5), pp.477-486. ⟨10.1111/cge.12972⟩
International audience; WNT10A gene encodes a canonical wingless pathway signaling molecule involved in cell fate specification as well as morphogenetic patterning of the developing ectoderm, nervous system, skeleton, and tooth. In patients, WNT10A m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::719d480177fcd04a6a9e2c362e9a5428
https://hal-univ-tlse3.archives-ouvertes.fr/hal-03282733
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6
Wnt6 activates endoderm in the sea urchin gene regulatory network
Autor: David R. McClay, Esther Miranda, Thierry Lepage, Jenifer C. Croce, Jeff Chieh-fu Peng, Guy Lhomond, Ryan C. Range, Shu-Yu Wu
Publikováno v: Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2011, 138 (15), pp.3297-3306. ⟨10.1242/dev.058792⟩
Development (Cambridge, England), 2011, 138 (15), pp.3297-3306. ⟨10.1242/dev.058792⟩
International audience; In the sea urchin, entry of β-catenin into the nuclei of the vegetal cells at 4th and 5th cleavages is necessary for activation of the endomesoderm gene regulatory network. Beyond that, little is known about how the embryo us
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9cb913e502477fd1772b2f3dd41814
https://doi.org/10.1242/dev.058792
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7
A new mechanism of SOX9 action to regulate PKCα expression in the intestine epithelium
Autor: Corinne Quittau-Prévostel, Vincent Cavaillès, Robert I. Glazer, Philippe Jay, Rana Abdel-Samad, Dominique Joubert, Sébastien Dupasquier, Pauline Bastide, Philippe Blache
Publikováno v: Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2009, 122 (13), pp.2191-2196. ⟨10.1242/jcs.036483⟩
International audience; Variations of protein kinase C (PKC) expression greatly influence the proliferation-to-differentiation transition (PDT) of intestinal epithelial cells and might have an important impact on intestinal tumorigenesis. We demonstr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd453df12471a9b15f25fbb1f7d9e606
https://doi.org/10.1242/jcs.036483
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8
N-Cadherin Interacts with Axin and LRP5 To Negatively Regulate Wnt/β-Catenin Signaling, Osteoblast Function, and Bone Formation
Autor: Valerie Geoffroy, Pierre J. Marie, Thomas Kohler, Ralph Müller, Eric Hay, Emmanuel Laplantine, Monique Frain
Publikováno v: Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2009, 29 (4), pp.953-964. ⟨10.1128/MCB.00349-08⟩
International audience; Wnt signaling plays an important role in the regulation of bone formation and bone mass. The mechanisms that regulate canonical Wnt signaling in osteoblasts are not fully understood. We show here a novel mechanism by which the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cff56fa7fbc8affc31647cd6161bf5b
https://doi.org/10.1128/mcb.00349-08
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9
Hairy2–Id3 interactions play an essential role in Xenopus neural crest progenitor specification
Autor: Eric Bellefroid, Xi Ren, Noémie de Crozé, Anne H. Monsoro-Burq, Jacob Souopgui, Massimo Nichane
Publikováno v: Developmental Biology
Developmental Biology, Elsevier, 2008, 322 (2), pp.355-67. ⟨10.1016/j.ydbio.2008.08.003⟩
International audience; Loss of function studies have shown that the Xenopus helix-loop-helix transcription factor Hairy2 is essential for neural crest formation and maintains cells in a mitotic undifferentiated state. However, its position in the ge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c0dbca8ef2dac97cd6de60085417f1
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10
In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies
Autor: Iva Simeonova, Emmanuelle Huillard
Publikováno v: Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, Springer Verlag, 2014, 71 (20), pp.4007-4026. ⟨10.1007/s00018-014-1675-3⟩
Cellular and Molecular Life Sciences, 2014, 71 (20), pp.4007-4026. ⟨10.1007/s00018-014-1675-3⟩
International audience; Although our knowledge of the biology of brain tumors has increased tremendously over the past decade, progress in treatment of these deadly diseases remains modest. Developing in vivo models that faithfully mirror human disea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a40be64c905dd64fb9d30a9c913fe5d
https://hal.archives-ouvertes.fr/hal-03043040
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