Zobrazeno 1 - 10 of 11 pro vyhledávání: '"MESH: Valproic Acid"'
1
Prescribing Trends for Valproate Among Pregnant Women: A Cross-sectional Study in 2013 and 2016 Using the French Health Insurance Database
Autor: Adeline Degremont, Sandrine Kerbrat, Frédéric Balusson, Annie Pierre Jonville-Bera, Virginie Ringa, David Travers, Hélène Tillaut, Emmanuelle Leray, Emmanuel Oger, Arnaud Biraben, Elisabeth Polard
Publikováno v: Neurology
Neurology, 2022, 98 (21), pp.e2163-e2173. ⟨10.1212/WNL.0000000000200260⟩
Neurology, American Academy of Neurology, 2022, 98 (21), pp.e2163-e2173. ⟨10.1212/WNL.0000000000200260⟩
Background and ObjectiveTo describe the prescribing trends for sodium valproate (VPA) and alternative drugs during and around pregnancy, comparing 2016 (after the recommendations on valproate for women were reinforced by the European Medicines Agency
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed0f479c74c60cb9cbb64233e804c5d
https://hal.ehesp.fr/hal-03637138
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3
Human Pluripotent Stem Cell-derived Cortical Neurons for High Throughput Medication Screening in Autism: A Proof of Concept Study in SHANK3 Haploinsufficiency Syndrome
Autor: Aurélie Poulet, Alexandra Benchoua, Richard Delorme, Laure Chatrousse, Francis Cogé, Delphine Héron, Frédérique Rodet-Amsellem, Millan Mark, Claire Boissart, Thomas Bourgeron, Hélène Darville, Anselme L. Perrier, Caroline Nava, Julie Pernelle, Margot Jarrige, Marc Peschanski
Publikováno v: EBioMedicine
EBioMedicine, 2016, 9, pp.293-305. ⟨10.1016/j.ebiom.2016.05.032⟩
EBioMedicine, Elsevier, 2016, 9, pp.293-305. ⟨10.1016/j.ebiom.2016.05.032⟩
EBioMedicine, Vol 9, Iss C, Pp 293-305 (2016)
Autism spectrum disorders affect millions of individuals worldwide, but their heterogeneity complicates therapeutic intervention that is essentially symptomatic. A versatile yet relevant model to rationally screen among hundreds of therapeutic option
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fbe8b05a4f882b42c33ec304afa3e8
https://hal.sorbonne-universite.fr/hal-01326262/file/S2352396416302286.pdf
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4
HDAC inhibitors induce apoptosis in glucocorticoid-resistant acute lymphatic leukemia cells despite a switch from the extrinsic to the intrinsic death pathway
Autor: Fabio Manzo, Hinrich Gronemeyer, Patrick Lutz, Michele Lieb, Pattabhiraman Shankaranarayanan, Raoul Herbrecht, Michael Tsapis
Publikováno v: International Journal of Biochemistry and Cell Biology
International Journal of Biochemistry and Cell Biology, Elsevier, 2007, 39 (7-8), pp.1500-9. ⟨10.1016/j.biocel.2007.03.009⟩
Inhibitors of histone deacetylases (HDACi's) are promising novel tools for cancer therapy. We have compared the growth inhibitory and apoptogenic potential of the pan-HDACi SAHA and the sub-class I selective HDAC inhibitor MS275, as well as valproic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb93f7491a82b5c2ad4d74945cb3c883
https://doi.org/10.1016/j.biocel.2007.03.009
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5
Effects of valproate on Tax and HBZ expression in HTLV-1 and HAM/TSP T lymphocytes
Autor: Maryvonne Dueymes, Antoine Gross, Stéphane Olindo, Raymond Césaire, Yuetsu Tanaka, Jean-Michel Mesnard, Luc Willems, Agnès Lézin, Isabelle Komla-Soukha, Didier Smadja, Jean-Marie Peloponese, Gildas Belrose
Publikováno v: Blood
Blood, American Society of Hematology, 2011, 118 (9), pp.2483-2491. ⟨10.1182/blood-2010-11-321364⟩
Blood, 2011, 118 (9), pp.2483-2491. ⟨10.1182/blood-2010-11-321364⟩
Europe PubMed Central
A determinant of human T-lymphotropic virus-1 (HTLV-1)–associated myelopathy/tropical spastic paraparesis (HAM/TSP) development is the HTLV-1–infected cell burden. Viral proteins Tax and HBZ, encoded by the sense and antisense strands of the pX r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ac450effa6589fb0d489f18fd4c686
https://hal.archives-ouvertes.fr/hal-02152775
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6
Adherence to guidelines by French psychiatrists in their real world of clinical practice
Autor: Ludovic Samalin, Pierre-Michel Llorca, Sébastien Guillaume, Candy Auclair
Publikováno v: The Journal of nervous and mental disease
The Journal of nervous and mental disease, 2011, 199 (4), pp.239-43. ⟨10.1097/NMD.0b013e3182125d4c⟩
International audience; The treatment modalities of bipolar disorder and adherence to international guidelines recommendations in France were investigated. We conducted an observational survey among 210 French psychiatrists concerning their prescribi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f890b0f8746ced377fbeb17e09818fc
https://pubmed.ncbi.nlm.nih.gov/21451347
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7
HDACs link the DNA damage response, processing of double-strand breaks and autophagy
Autor: Irene Chiolo, Marco Foiani, Kara A. Bernstein, Amanda Oldani, Oronza A. Botrugno, Dario Parazzoli, Ghadeer Shubassi, Fabio Vanoli, Saverio Minucci, Thomas Robert, Rodney Rothstein
Publikováno v: Nature
Nature, Nature Publishing Group, 2011, 471 (7336), pp.74-79. ⟨10.1038/nature09803⟩
International audience; Protein acetylation is mediated by histone acetyltransferases (HATs) and deacetylases (HDACs), which influence chromatin dynamics, protein turnover and the DNA damage response. ATM and ATR mediate DNA damage checkpoints by sen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77d63b3c64ed1dfa5006f7ad9dae64f
https://hal.archives-ouvertes.fr/hal-03454096
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8
Highly active antiretroviral treatment against STLV-1 infection combining reverse transcriptase and HDAC inhibitors
Autor: Franck Mortreux, Philippe V. Afonso, Antoine Moriceau, Antoine Gessain, Frederic Toulza, Charles R. M. Bangham, Yves Plumelle, Eric Wattel, Mourad Mekaouche, Renaud Mahieux, Jérôme Estaquier, Olivier Hermine, Guy Dubreuil
Publikováno v: Blood
Blood, American Society of Hematology, 2010, 116 (19), pp.3802-8. ⟨10.1182/blood-2010-02-270751⟩
Blood, 2010, 116 (19), pp.3802-8. ⟨10.1182/blood-2010-02-270751⟩
Blood, American Society of Hematology, 2010, 116, pp.3802-3808
Approximately 3% of all human T-lymphotropic virus type 1 (HTLV-1)–infected persons will develop a disabling inflammatory disease of the central nervous system known as HTLV-1–associated myelopathy/tropical spastic paraparesis, against which ther
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c0513ac4f6bdcf9b00e77f040d5735
https://hal-pasteur.archives-ouvertes.fr/pasteur-00507417
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9
Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias
Autor: Iolanda Mazzucchelli, Isabel Jorquera, Jean Bernard Manent, Antoine Depaulis, Yehezkel Ben-Ari, Alfonso Represa, Emilio Perucca
Publikováno v: Epilepsia
Epilepsia, Wiley, 2007, 48 (4), pp.684-93. ⟨10.1111/j.1528-1167.2007.01056.x⟩
Epilepsia, 2007, 48 (4), pp.684-93. ⟨10.1111/j.1528-1167.2007.01056.x⟩
Summary: Purpose: The management of epilepsy during pregnancy entails a number of concerns. While seizures may affect adversely maternal and fetal outcome, antiepileptic drugs (AEDs) may increase the incidence of congenital abnormalities and possibly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3832452f401f772430209fc96bc8f32d
https://www.hal.inserm.fr/inserm-00384325
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10
The effect on vision of associated treatments in patients taking vigabatrin: carbamazepine versus valproate
Autor: Marc Salle, J C Hache, Philippe Derambure, Carl Arndt, Sabine Defoort-Dhellemmes
Publikováno v: Epilepsia
Epilepsia, Wiley, 2002, 43 (8), pp.812-7
Summary: Purpose: To evaluate the effect on visual function of a concomitant antiepileptic drug (AED) in patients treated with vigabatrin (VGB). Methods: Sixty-four consecutive patients with a history of partial seizures currently treated with VGB wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d129df6c0ce255813c07bcc7f4fb6578
https://hal.archives-ouvertes.fr/hal-00346432
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