Výsledky vyhledávání - "MESH: Tyrosine"

L-tyrosine-bound ThiH structure reveals C-C bond break differences within radical SAM aromatic amino acid lyases

Autor: Patricia Amara, Claire Saragaglia, Jean-Marie Mouesca, Lydie Martin, Yvain Nicolet

Publikováno v: Nature Communications
Nature Communications, 2022, 13 (1), pp.2284. ⟨10.1038/s41467-022-29980-4⟩

2-iminoacetate synthase ThiH is a radical S-adenosyl-L-methionine (SAM) L-tyrosine lyase and catalyzes the L-tyrosine Cα–Cβ bond break to produce dehydroglycine and p-cresol while the radical SAM L-tryptophan lyase NosL cleaves the L-tryptophan C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300785c8e8b59f75ab19d81a0e23c253
https://pubmed.ncbi.nlm.nih.gov/35477710

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A targeted ultra performance liquid chromatography – Tandem mass spectrometric assay for tyrosine and metabolites in urine and plasma: Application to the effects of antibiotics on mice

Autor: Dumas, Marc-Emmanuel, Letertre, Marine, Myridakis, Antonis, Whiley, Luke, Camuzeaux, Stéphane, Lewis, Matthew, Chappell, Katie, Thaikkatil, Annie, Nicholson, Jeremy, Swann, Jonathan, Wilson, Ian, Letertre, Marine P.M.

Publikováno v: Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, Elsevier, 2021, 1164, pp.122511. ⟨10.1016/j.jchromb.2020.122511⟩
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 2021, 1164, pp.122511. ⟨10.1016/j.jchromb.2020.122511⟩

International audience; Tyrosine plays a key role in mammalian biochemistry and defects in its metabolism (e.g., tyrosinemia, alkaptonuria etc.) have significant adverse consequences for those affected if left untreated. In addition, gut bacterially-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ae496d3bcfcb17f38e189cc666d9c7
https://hal-cnrs.archives-ouvertes.fr/hal-03451217

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Endocytosis of BRASSINOSTEROID INSENSITIVE1 Is Partly Driven by a Canonical Tyr-Based Motif

Autor: Isabelle Vanhoutte, Eugenia Russinova, Lucas Alves Neubus Claus, Rajesh Kumar, Peng Wang, Wei Siao, Daniël Van Damme, Jiří Friml, Derui Liu, Xiuyang Zhao, Grégory Vert, Alexander W. Johnson, Klaas Yperman, Sara Martins, Kyle W. Bender

Publikováno v: The Plant cell
The Plant cell, 2020, 32 (11), pp.3598-3612. ⟨10.1105/tpc.20.00384⟩
The Plant cell, American Society of Plant Biologists (ASPB), 2020, 32 (11), pp.3598-3612. ⟨10.1105/tpc.20.00384⟩
The Plant Cell
Plant Cell
PLANT CELL

Clathrin-mediated endocytosis (CME) and its core endocytic machinery are evolutionarily conserved across all eukaryotes. In mammals, the heterotetrameric adaptor protein complex-2 (AP-2) sorts plasma membrane (PM) cargoes into vesicles via the recogn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec08c8065097cd661ef9eb3cf1e34d47
https://ut3-toulouseinp.hal.science/hal-03361355

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Treatment with synthetic lipophilic tyrosyl ester controls Leishmania major infection by reducing parasite load in BALB/c mice

Autor: Fatma Z. Guerfali, Hanène Attia, Youssef Gargouri, Pablo A. Leon Martinez, Ghada Mkannez, Aymen Bali, Dhafer Laouini, Imen Aissa, Rabiaa M. Sghaier

Publikováno v: Parasitology
Parasitology, Cambridge University Press (CUP), 2016, 143 (12), pp.1615-1620. ⟨10.1017/S0031182016001086⟩

SUMMARYSynthesized lipophilic tyrosyl ester derivatives with increasing lipophilicity were effective against Leishmania (L.) major and Leishmania infantum species in vitro. These findings prompted us to test in vivo leishmanicidal properties of these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bc2abccdcddddc96eac44eca020091
https://doi.org/10.1017/s0031182016001086

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BEST and SOFAST experiments for resonance assignment of histidine and tyrosine side chains in 13C/15N labeled proteins

Autor: Nina Eleni Christou, Bernhard Brutscher

Publikováno v: Journal of Biomolecular NMR
Journal of Biomolecular NMR, 2018, 72 (3-4), pp.115-124. ⟨10.1007/s10858-018-0216-z⟩
Journal of Biomolecular NMR, Springer Verlag, 2018, 72 (3-4), pp.115-124. ⟨10.1007/s10858-018-0216-z⟩

International audience; Aromatic amino-acid side chains are essential components for the structure and function of proteins. We present herein a set of NMR experiments for time-efficient resonance assignment of histidine and tyrosine side chains in u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b7c57f709ae90d2d777a21bd05b950
https://hal.science/hal-02085961

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Tyrosine-1 of RNA Polymerase II CTD Controls Global Termination of Gene Transcription in Mammals

Autor: Amal Zine El Aabidine, Dirk Eick, David C. Martin, Cyril Esnault, Yousra Yahia, Jean-Christophe Andrau, Nilay Shah, Roland Schüller, Stefan Krebs, Tim-Michael Decker, Helmut Blum, Axel Imhof, Muhammad Ahmad Maqbool, Ignasi Forné

Publikováno v: Molecular Cell
Molecular Cell, Elsevier, 2018, 69 (1), pp.48-61.e6. ⟨10.1016/j.molcel.2017.12.009⟩

International audience; The carboxy-terminal domain (CTD) of RNA polymerase (Pol) II is composed of a repetition of YSPTSPS heptads and functions as a loading platform for protein complexes that regulate transcription, splicing, and maturation of RNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f4402762541441e8a275ce3776ef9d
https://hal.archives-ouvertes.fr/hal-03022268

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RadicalS-Adenosyl-l-Methionine Carbon Monoxide and Cyanide Synthase HydG

Autor: Juan C. Fontecilla-Camps, Yvain Nicolet

Publikováno v: Encyclopedia of Inorganic and Bioinorganic Chemistry
Encyclopedia of Inorganic and Bioinorganic Chemistry, 2017, ⟨10.1002/9781119951438.eibc2506⟩

International audience; Crystal structures of [FeFe]-hydrogenases have revealed complex coordination of their active site [FeFe] motif. Besides a dithiomethylamine (DTMA) ligand that bridges the two iron ions through its thiolate groups, each metal h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67d9a155db899ebd3e374cb0852de38
https://doi.org/10.1002/9781119951438.eibc2506

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Tyrosine-Nitrated Proteins: Proteomic and Bioanalytical Aspects

Autor: BatthyányCarlos, DemicheliVerónica, RadiRafael, MastrogiovanniMauricio, LimaAnalía, BartesaghiSilvina

Publikováno v: Antioxidants and Redox Signaling
Antioxidants and Redox Signaling, Mary Ann Liebert, 2017, 26 (7), pp.313-328. ⟨10.1089/ars.2016.6787⟩

"Nitroproteomic" is under active development, as 3-nitrotyrosine in proteins constitutes a footprint left by the reactions of nitric oxide-derived oxidants that are usually associated to oxidative stress conditions. Moreover, protein tyrosine nitrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a761a64289ca44d2f97d3f0a039c08
https://hal-riip.archives-ouvertes.fr/pasteur-01498316

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Roles of Retinoic Acid Signaling in Shaping the Neuronal Architecture of the Developing Amphioxus Nervous System

Autor: Jenifer C. Croce, Greta Garbarino, Elisabeth Zieger, Simona Candiani, Michael Schubert

Publikováno v: Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2018, 55 (6), pp.5210-5229. ⟨10.1007/s12035-017-0727-8⟩

International audience; The morphogen retinoic acid (RA) patterns vertebrate nervous systems and drives neurogenesis, but how these functions evolved remains elusive. Here, we show that RA signaling plays stage- and tissue-specific roles during the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8450a8806ec07d649675bf336856a632
https://pubmed.ncbi.nlm.nih.gov/29429050

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SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation

Autor: Zong-Bo Wei, Wei Li, Zengqiang Yuan, Corinne Beurrier, Chanjuan Hao, Zhe Zhang, Li Yu, Florence Jaouen, Meisheng Ma, Yefeng Yuan, Quan Chen

Publikováno v: Autophagy
Autophagy, Taylor & Francis, 2016, 12 (7), pp.1168-1179. ⟨10.1080/15548627.2016.1179402⟩
Autophagy, 2016, 12 (7), pp.1168-1179. ⟨10.1080/15548627.2016.1179402⟩

International audience; Searching for new regulators of autophagy involved in selective dopaminergic (DA) neuron loss is a hallmark in the pathogenesis of Parkinson disease (PD). We here report that an endoplasmic reticulum (ER)-associated transmembr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0388d1c1d4c01f29863735157a49a82d
https://hal.archives-ouvertes.fr/hal-03079432

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