Zobrazeno 1 - 10
of 138
pro vyhledávání: '"MESH: Tumor Suppressor Protein p53"'
Autor:
Vincent Cavaillès, Sandrine Bonnet, Laetitia K. Linares, Catherine Teyssier, Valentin Jacquier, Delphine Gitenay, Balazs Gyorffy, Samuel Fritsch, Stéphan Jalaguier
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, Springer Verlag, 2022, 79 (5), pp.270. ⟨10.1007/s00018-022-04277-3⟩
Cellular and Molecular Life Sciences, Springer Verlag, 2022, 79 (5), pp.270. ⟨10.1007/s00018-022-04277-3⟩
Cancer cells with uncontrolled proliferation preferentially depend on glycolysis to grow, even in the presence of oxygen. Cancer cell proliferation is sustained by the production of glycolytic intermediates, which are diverted into the pentose phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa8d8653cda888cef6850f9531c1ecb
https://hal.umontpellier.fr/hal-03858446/file/s00018-022-04277-3.pdf
https://hal.umontpellier.fr/hal-03858446/file/s00018-022-04277-3.pdf
Autor:
Kiersten M. Ruff, Tamas Lazar, Claudiu C. Gradinaru, María Silvina Fornasari, Silvio C. E. Tosatto, Javier Iserte, Marie Skepö, Julia Marchetti, Sonia Longhi, Teresa Head-Gordon, Toby J. Gibson, Nicolás A. Méndez, Gregory-Neal W. Gomes, Malene Ringkjøbing Jensen, Nicolás A. Garrone, Pau Bernadó, Martin Blackledge, Alexander Miguel Monzon, Dmitri I. Svergun, András Hatos, Julie D. Forman-Kay, Cristina Marino-Buslje, Edward A. Lemke, Eric Fagerberg, Ana Julia Velez Rueda, Sylvain D. Vallet, Elizabeth Martínez-Pérez, Sylvie Ricard-Blum, Tiago N. Cordeiro, Federica Quaglia, Tadeo E. Saldaño, Damiano Piovesan, Peter Tompa, Tanja Mittag, Gustavo Parisi, Mihaly Varadi, Rohit V. Pappu, Lucía B. Chemes, Giovanni Minervini, Edoardo Salladini
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2021, 49 (D1), pp.D404-D411. ⟨10.1093/nar/gkaa1021⟩
Nucleic acids research, vol 49, iss D1
Nucleic Acids Research, 2021, 49 (D1), pp.D404-D411. ⟨10.1093/nar/gkaa1021⟩
Nucleic Acids Research, Oxford University Press, In press, ⟨10.1093/nar/gkaa1021⟩
Nucleic Acids Research, In press, ⟨10.1093/nar/gkaa1021⟩
Nucleic Acids Research, Oxford University Press, 2021, 49 (D1), pp.D404-D411. ⟨10.1093/nar/gkaa1021⟩
Nucleic acids research, vol 49, iss D1
Nucleic Acids Research, 2021, 49 (D1), pp.D404-D411. ⟨10.1093/nar/gkaa1021⟩
Nucleic Acids Research, Oxford University Press, In press, ⟨10.1093/nar/gkaa1021⟩
Nucleic Acids Research, In press, ⟨10.1093/nar/gkaa1021⟩
The Protein Ensemble Database (PED) (https://proteinensemble.org), which holds structural ensembles of intrinsically disordered proteins (IDPs), has been significantly updated and upgraded since its last release in 2016. The new version, PED 4.0, has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62579a66daeda9d1cb3ef52f41885bf
https://hal.univ-grenoble-alpes.fr/hal-03433964/document
https://hal.univ-grenoble-alpes.fr/hal-03433964/document
Autor:
Pondrom, Morgane, Bougeard, Gaëlle, Karanian, Marie, Bonneau-Lagacherie, Jacynthe, Boulanger, Cecile, Boutroux, Hélène, Briandet, Claire, Chevreau, Christine, Corradini, Nadège, Coze, Carole, Defachelles, Anne Sophie, Galmiche-Roland, Louise, Orbach, Daniel, Piguet, Christophe, Scoazec, Jean Yves, Vérité, Cécile, Willems, Marjolaine, Frebourg, Thierry, Minard, Véronique, Brugières, Laurence, Bonneau‐Lagacherie, Jacynthe, Galmiche‐Roland, Louise
Publikováno v:
Pediatric Blood and Cancer
Pediatric Blood and Cancer, Wiley, 2020, 67 (9), pp.e28486. ⟨10.1002/pbc.28486⟩
Pediatric Blood and Cancer, Wiley, 2020, 67 (9), pp.e28486. ⟨10.1002/pbc.28486⟩
Objective To describe the clinical characteristics and outcome of patients with Li-Fraumeni-associated rhabdomyosarcoma (RMS). Method Retrospective analysis of data from 31 French patients with RMS diagnosed before the age of 20 years associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8907056d28f73f9cbfe780a4fdf9c5
https://doi.org/10.1002/pbc.28486
https://doi.org/10.1002/pbc.28486
Autor:
Susan M. Mason, John R. P. Knight, Arnaud Echard, Giuseppina Caligiuri, Dide Reijmer, Monika Calka, Flore Kruiswijk, David Sumpton, David Novo, Karen Blyth, Iain R. Macpherson, Karen H. Vousden, Peter Bailey, Sara Zanivan, Kerstin Klinkert, Jim C. Norman, Judith Secklehner, Amanda MacFarlane, Nikki Heath, Huabing Yin, Jennifer P. Morton, Leo M. Carlin, Louise Mitchell, Ewan J. McGhee, Laura Charlton, Emmanuel Dornier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.5069. ⟨10.1038/s41467-018-07339-y⟩
Nature Communications, 2018, 9 (1), pp.5069. ⟨10.1038/s41467-018-07339-y⟩
Novo, D, Heath, N, Mitchell, L, Caligiuri, G, MacFarlane, A, Reijmer, D, Charlton, L, Knight, J, Calka, M, McGhee, E, Dornier, E, Sumpton, D, Mason, S, Echard, A, Klinkert, K, Secklehner, J, Kruiswijk, F, Vousden, K, Macpherson, I R, Blyth, K, Bailey, P, Yin, H, Carlin, L M, Morton, J, Zanivan, S & Norman, J C 2018, ' Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels ', Nature Communications, vol. 9, no. 1, 5069 . https://doi.org/10.1038/s41467-018-07339-y
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.5069. ⟨10.1038/s41467-018-07339-y⟩
Nature Communications, 2018, 9 (1), pp.5069. ⟨10.1038/s41467-018-07339-y⟩
Novo, D, Heath, N, Mitchell, L, Caligiuri, G, MacFarlane, A, Reijmer, D, Charlton, L, Knight, J, Calka, M, McGhee, E, Dornier, E, Sumpton, D, Mason, S, Echard, A, Klinkert, K, Secklehner, J, Kruiswijk, F, Vousden, K, Macpherson, I R, Blyth, K, Bailey, P, Yin, H, Carlin, L M, Morton, J, Zanivan, S & Norman, J C 2018, ' Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels ', Nature Communications, vol. 9, no. 1, 5069 . https://doi.org/10.1038/s41467-018-07339-y
Mutant p53s (mutp53) increase cancer invasiveness by upregulating Rab-coupling protein (RCP) and diacylglycerol kinase-α (DGKα)-dependent endosomal recycling. Here we report that mutp53-expressing tumour cells produce exosomes that mediate intercel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4508e22176087bbcbdf320820985074e
http://link.springer.com/article/10.1038/s41467-018-07339-y
http://link.springer.com/article/10.1038/s41467-018-07339-y
Autor:
Mariette Matondo, Bernard Monsarrat, Odile Burlet-Schiltz, Marlène Marcellin, Marie-Pierre Bousquet-Dubouch, Karima Chaoui, Anne Gonzalez-de-Peredo
Publikováno v:
Proteomics
Proteomics, Wiley-VCH Verlag, 2017, Applications and Developments in Targeted Proteomics, 17 (7), pp.1600089. ⟨10.1002/pmic.201600089⟩
Proteomics, Wiley-VCH Verlag, 2017, Applications and Developments in Targeted Proteomics, 17 (7), pp.1600089. ⟨10.1002/pmic.201600089⟩
International audience; The ubiquitin-proteasome pathway (UPP) plays a critical role in the degradation of proteins implicated in cell cycle control, signal transduction, DNA damage response, apoptosis and immune response. Proteasome inhibitors can i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46ca49bbfe534e269c497edfc5fdec0
https://hal-pasteur.archives-ouvertes.fr/pasteur-02619400/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-02619400/document
Autor:
Laetitia K. Linares, Andrew V. Hubberstey, Emmanuelle Liaudet-Coopman, Nelly Pirot, Fabienne Desmots, Guy Berchem, Anne-Sophie Bach, Esther Pérez-Gracia, Christine Prébois, Valérie Palissot, Patrice Codogno, Céline Gongora, Salwa Sebti, Sophie Pattingre, Chantal Bauvy
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (11), pp.4115-20. 〈10.1073/pnas.1313618111〉
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (11), pp.4115-20. ⟨10.1073/pnas.1313618111⟩
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (11), pp.4115-20. ⟨10.1073/pnas.1313618111⟩
Biological Sciences Publications
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (11), pp.4115-20. 〈10.1073/pnas.1313618111〉
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2014, 111 (11), pp.4115-20. ⟨10.1073/pnas.1313618111⟩
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (11), pp.4115-20. ⟨10.1073/pnas.1313618111⟩
Biological Sciences Publications
International audience; Autophagy is regulated by posttranslational modifications, including acetylation. Here we show that HLA-B-associated transcript 3 (BAT3) is essential for basal and starvation-induced autophagy in embryonic day 18.5 BAT3(-/-) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cbd9bbdfb06ff6067a9638666a9d10
https://doi.org/10.1073/pnas.1313618111
https://doi.org/10.1073/pnas.1313618111
Autor:
Aubin Béré, Pascal Pineau, Paul Jean Adrien Atangana, Dominique Noah Noah, Claudine Bekondi, Narcisse-Patrice Komas, Marie Amougou Atsama, Agnès Marchio, Richard Njouom, Serge-Magloire Camengo-Police
Publikováno v:
Clinical and Experimental Medicine
Clinical and Experimental Medicine, Springer Verlag, 2018, 18 (3), pp.421-431. ⟨10.1007/s10238-018-0502-9⟩
Clinical and Experimental Medicine, 2018, 18 (3), pp.421-431. ⟨10.1007/s10238-018-0502-9⟩
Clinical and Experimental Medicine, Springer Verlag, 2018, 18 (3), pp.421-431. ⟨10.1007/s10238-018-0502-9⟩
Clinical and Experimental Medicine, 2018, 18 (3), pp.421-431. ⟨10.1007/s10238-018-0502-9⟩
International audience; Hepatocellular carcinoma (HCC) is still a major killing malignancy in sub-Saharan Africa. Lifelong intoxication with aflatoxin B1 is considered as one of the primary causes of this situation. The role of aflatoxin in HCC from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0243714b8db486523f54ee36267f9f89
https://hal-pasteur.archives-ouvertes.fr/pasteur-02611946/file/Marchio2018_Article_DropletDigitalPCRDetectsHighRa.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-02611946/file/Marchio2018_Article_DropletDigitalPCRDetectsHighRa.pdf
Autor:
Ligia Pereira Castro, Vanesa Gottifredi, Alain Sarasin, Alexandre T. Vessoni, Guilherme Francisco, Silvina Odete Bustos, Annabel Quinet, Daniela T. Soltys, Roger Chammas, Taynah I.P. David, Leticia K. Lerner, Bryan E. Strauss, Carlos Frederico Martins Menck, Anne Stary, Clarissa Ribeiro Reily Rocha
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2017, 45 (3), pp.1270-1280. ⟨10.1093/nar/gkw1196⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Universidade de São Paulo (USP)
instacron:USP
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2017, 45 (3), pp.1270-1280. ⟨10.1093/nar/gkw1196⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Genome lesions trigger biological responses that help cells manage damaged DNA, improving cell survival. Pol eta is a translesion synthesis (TLS) polymerase that bypasses lesions that block replicative polymerases, avoiding continued stalling of repl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c632e78bf42211a64ddaf21fcf039d4
Autor:
Marie-Laure Plissonnier, Nicolas Clere, Maëlle Saunier, Laurent Bermont, Isabelle Lascombe, Sylvie Fauconnet, Lucie Vettoretti, Christiane Mougin
Publikováno v:
Experimental Cell Research
Experimental Cell Research, Elsevier, 2007, 313 (15), pp.3239-50. 〈10.1016/j.yexcr.2007.06.029〉
Experimental Cell Research, Elsevier, 2007, 313 (15), pp.3239-50. ⟨10.1016/j.yexcr.2007.06.029⟩
Experimental Cell Research, Elsevier, 2007, 313 (15), pp.3239-50. 〈10.1016/j.yexcr.2007.06.029〉
Experimental Cell Research, Elsevier, 2007, 313 (15), pp.3239-50. ⟨10.1016/j.yexcr.2007.06.029⟩
International audience; Altered angiogenic response is associated with high-grade cervical dysplasia and with invasive squamous carcinoma of the cervix. Vascular Endothelial Growth Factor (VEGF) is one of the most potent inducers of angiogenesis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0f38cd76c8f69bbfa93497f4aea0ff
https://doi.org/10.1016/j.yexcr.2007.06.029
https://doi.org/10.1016/j.yexcr.2007.06.029
Autor:
Sylvie Fauconnet, Christiane Mougin, Jean-Luc Prétet, Mourboul Ablise, François Hermetet, Dominique A. Vuitton, Fabienne Hirchaud
Publikováno v:
Planta Medica
Planta Medica, Georg Thieme Verlag, 2013, 79 (17), pp.1628-1635. ⟨10.1055/s-0033-1350956⟩
Planta Medica, Georg Thieme Verlag, 2013, 79 (17), pp.1628-1635. ⟨10.1055/s-0033-1350956⟩
International audience; Flavonoids have antitumoral properties and may be attractive candidates as anticancer therapy. Isoliquiritigenin which is a constituent of licorice (Glycyrrhiza inflata), a plant commonly used in traditional Uyghur medicine in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1134c441da0bd144fc02a5f13e1838
https://doi.org/10.1055/s-0033-1350956
https://doi.org/10.1055/s-0033-1350956