Zobrazeno 1 - 10
of 27
pro vyhledávání: '"MESH: Tumor Microenvironment"'
Autor:
Alice Mogenet, Fabrice Barlesi, Benjamin Besse, Stefan Michiels, Maryam Karimi, Alicia Tran-Dien, Nicolas Girard, Julien Mazieres, Clarisse Audigier-Valette, Myriam Locatelli-Sanchez, Maud Kamal, Pierre Gestraud, Abderaouf Hamza, Alexandra Jacquet, Marta Jimenez, Sabrina Yara, Laurent Greillier, François Bertucci, David Planchard, Jean-Charles Soria, Ivan Bieche, Pascale Tomasini
Publikováno v:
Lung Cancer
Lung Cancer, 2022, 169, pp.31-39. ⟨10.1016/j.lungcan.2022.05.004⟩
Lung Cancer, 2022, 169, pp.31-39. ⟨10.1016/j.lungcan.2022.05.004⟩
Lung cancer remains the most frequent cause of brain metastases (BMs) and is responsible for high morbidity and mortality. Intracranial response to systemic treatments is inconsistent due to several mechanisms: genomic heterogeneity, blood-tumor barr
Autor:
Jary, Marine, Liu, Wen-Wei, Yan, Dongyao, Bai, Isaac, Muranyi, Andrea, Colle, Elise, Brocheriou, Isabelle, Turpin, Anthony, Radosevic-Robin, Nina, Bourgoin, Pierre, Penault-Llorca, Frédérique, Cohen, Romain, Vernerey, Dewi, André, Thierry, Borg, Christophe, Shanmugam, Kandavel, Svrcek, Magali, Liu, Wen‐wei
Publikováno v:
Molecular Oncology
Molecular Oncology, 2021, ⟨10.1002/1878-0261.13173⟩
Molecular Oncology, Elsevier, 2022, 16 (11), pp.2260-2273. ⟨10.1002/1878-0261.13173⟩
Molecular Oncology, 2022, 16 (11), pp.2260-2273. ⟨10.1002/1878-0261.13173⟩
Molecular Oncology, Elsevier, 2021, ⟨10.1002/1878-0261.13173⟩
Molecular Oncology, 2021, ⟨10.1002/1878-0261.13173⟩
Molecular Oncology, Elsevier, 2022, 16 (11), pp.2260-2273. ⟨10.1002/1878-0261.13173⟩
Molecular Oncology, 2022, 16 (11), pp.2260-2273. ⟨10.1002/1878-0261.13173⟩
Molecular Oncology, Elsevier, 2021, ⟨10.1002/1878-0261.13173⟩
International audience; In the era of immune checkpoint inhibitors, understanding the metastatic microenvironment of proficient mismatch repair/microsatellite stable (pMMR/MSS) colorectal cancer (CRC) is of paramount importance to both prognosticatio
Autor:
Yann-Alexandre Vano, Réza Elaidi, Mostefa Bennamoun, Christine Chevreau, Delphine Borchiellini, Diane Pannier, Denis Maillet, Marine Gross-Goupil, Christophe Tournigand, Brigitte Laguerre, Philippe Barthélémy, Elodie Coquan, Gwenaëlle Gravis, Nadine Houede, Mathilde Cancel, Olivier Huillard, Philippe Beuzeboc, Laure Fournier, Arnaud Méjean, Xavier Cathelineau, Nicolas Doumerc, Philippe Paparel, Jean-Christophe Bernhard, Alexandre de la Taille, Karim Bensalah, Thibault Tricard, Thibaut Waeckel, Géraldine Pignot, Elena Braychenko, Stefano Caruso, Cheng-Ming Sun, Virginie Verkarre, Guillaume Lacroix, Marco Moreira, Maxime Meylan, Antoine Bougouïn, Letuan Phan, Christelle Thibault-Carpentier, Jessica Zucman-Rossi, Wolf Herman Fridman, Catherine Sautès-Fridman, Stéphane Oudard
Publikováno v:
Lancet Oncology
Lancet Oncology, 2022, 23 (5), pp.612-624. ⟨10.1016/S1470-2045(22)00128-0⟩
Lancet Oncology, 2022, 23 (5), pp.612-624. ⟨10.1016/S1470-2045(22)00128-0⟩
International audience; Background: We previously reported a 35-gene expression classifier identifying four clear-cell renal cell carcinoma groups (ccrcc1 to ccrcc4) with different tumour microenvironments and sensitivities to sunitinib in metastatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a85c6d4558df8a8fb1a475ca37c2014
https://hal.science/hal-04072026
https://hal.science/hal-04072026
Publikováno v:
European Annals of Otorhinolaryngology, Head and Neck Diseases
European Annals of Otorhinolaryngology, Head and Neck Diseases, Elsevier Masson, 2020, 137 (5), pp.399-404. ⟨10.1016/j.anorl.2020.01.008⟩
European Annals of Otorhinolaryngology, Head and Neck Diseases, Elsevier Masson, 2020, 137 (5), pp.399-404. ⟨10.1016/j.anorl.2020.01.008⟩
International audience; Vocal-fold leukoplakia and dysplasia are together designated "epithelial hyperplastic laryngeal lesions" (EHLL). Work-up and follow-up are founded on optical examination with high-definition imaging, stroboscopy and narrow-ban
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9936ba0bb9bbcdc8e153432709e7ab04
https://hal.umontpellier.fr/hal-03483690
https://hal.umontpellier.fr/hal-03483690
Autor:
Emmanuel Cornillot, Vanessa Lacheretz-Szablewski, Valérie Costes-Martineau, Valérie Rigau, Valère Cacheux, Melissa Alame, Jacques Colinge
Publikováno v:
Theranostics
Theranostics, 2021, 11 (8), pp.3565-3579. ⟨10.7150/thno.54343⟩
Theranostics, 2021, 11 (8), pp.3565-3579. ⟨10.7150/thno.54343⟩
International audience; Rationale: Primary central nervous system diffuse large B-cell lymphoma (PCNSL) is a rare and aggressive entity that resides in an immune-privileged site. The tumor microenvironment (TME) and the disruption of the immune surve
Autor:
Stanislas Goriely, Marie-Véronique Joubert, Tobias Bald, Mark J. Smyth, Ludovic Martinet, Elena Morandi, Loïc Dupré, Laure Buisson, Nadège Carrié, Marianne Weulersse, Guillaume Gaud, Marie Le Moine, Thomas Gossye, Anne Dejean, Hervé Avet-Loiseau, Ashmitha Sundarrajan, Assia Asrir, Andrea C. Pichler, Michaël Pérès, Abdelhadi Saoudi, Alejandra Martinez, Julien Mazieres, Sahar Kassem, Elisa Brauns, Els Verhoeyen, Indrajit Das, Sabrina Maheo, Matthias Braun, Vera Pancaldi, Clara Maria Scarlata, Marine Cuisinier, Maha Ayyoub, Laura Do Souto, Lea Lemaitre, Arantxa Agesta, Camille Guillerey
Publikováno v:
Immunity, 53 (4
Immunity
Immunity, Elsevier, 2020, 53 (4), pp.824-839.e10. ⟨10.1016/j.immuni.2020.09.006⟩
Immunity, 2020, 53 (4), pp.824-839.e10. ⟨10.1016/j.immuni.2020.09.006⟩
Immunity
Immunity, Elsevier, 2020, 53 (4), pp.824-839.e10. ⟨10.1016/j.immuni.2020.09.006⟩
Immunity, 2020, 53 (4), pp.824-839.e10. ⟨10.1016/j.immuni.2020.09.006⟩
Through complementary approaches, involving cancer patients’ samples and relevant mouse tumor models, Weulersse et al. reveal that CD8 T cells in the tumor microenvironment lose expression of the activating receptor CD226 (DNAM-1) in a manner that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dfe5be6f45852b02f2ba60ac27610fa
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/316003
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/316003
Publikováno v:
Journal of Leukocyte Biology
Journal of Leukocyte Biology, 2020, 108 (4), pp.1067-1079. ⟨10.1002/JLB.1MR0520-746R⟩
Journal of Leukocyte Biology, 2020, 108 (4), pp.1067-1079. ⟨10.1002/JLB.1MR0520-746R⟩
Innovative immunotherapies based on immune checkpoint targeting antibodies and engineered T cells are transforming the way we approach cancer treatment. However, although these T cell centered strategies result in marked and durable responses in pati
Publikováno v:
Trends in Immunology
Trends in Immunology, 2019, 40 (11), pp.1022-1034. ⟨10.1016/j.it.2019.09.002⟩
Trends in Immunology, Elsevier, 2019, 40 (11), pp.1022-1034. ⟨10.1016/j.it.2019.09.002⟩
Trends in Immunology, 2019, 40 (11), pp.1022-1034. ⟨10.1016/j.it.2019.09.002⟩
Trends in Immunology, Elsevier, 2019, 40 (11), pp.1022-1034. ⟨10.1016/j.it.2019.09.002⟩
International audience; Understanding complex interactions between the immune system and the tumor microenvironment is an essential step towards the rational development and optimization of immunotherapies. Several experimental approaches are availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d75743cdf4d27917f9130917adc3a92c
https://hal-pasteur.archives-ouvertes.fr/pasteur-02944694/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-02944694/document
Autor:
Paula Y. Lam, Gwendal Lazennec
Publikováno v:
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, Elsevier, 2016, 1866 (2), pp.290-299. ⟨10.1016/j.bbcan.2016.10.004⟩
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, Elsevier, 2016, 1866 (2), pp.290-299. ⟨10.1016/j.bbcan.2016.10.004⟩
International audience; Tumor microenvironment plays a crucial role in coordination with cancer cells in the establishment, growth and dissemination of the tumor. Among cells of the microenvironment, mesenchymal stem cells (MSCs) and their ability to
Autor:
Raphaelle Fanciullino, Gérard Milano, Bruno Lacarelle, Guillaume Sicard, Joseph Ciccolini, Sebastien Benzekry, Anne Rodallec
Publikováno v:
Expert Opinion on Drug Metabolism and Toxicology
Expert Opinion on Drug Metabolism and Toxicology, Taylor & Francis, 2018, 14 (11), pp.1-9. ⟨10.1080/17425255.2018.1540588⟩
Expert Opinion on Drug Metabolism and Toxicology, 2018, 14 (11), pp.1-9. ⟨10.1080/17425255.2018.1540588⟩
Expert Opinion on Drug Metabolism and Toxicology, Taylor & Francis, 2018, 14 (11), pp.1-9. ⟨10.1080/17425255.2018.1540588⟩
Expert Opinion on Drug Metabolism and Toxicology, 2018, 14 (11), pp.1-9. ⟨10.1080/17425255.2018.1540588⟩
International audience; Immune checkpoint inhibitors have considerably changed the landscape of oncology. However apart from world-acclaimed success stories limited to melanoma and lung cancer, many solid tumors failed to respond to immune checkpoint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27cd0df783f987c93cbf5eaac74cad60
https://hal.inria.fr/hal-01958583/document
https://hal.inria.fr/hal-01958583/document