Výsledky vyhledávání - "MESH: Tryptophan Hydroxylase"

EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain

Autor: Patricia Gaspar, Teng Teng, Aude Muzerelle, Afsaneh Gaillard

Publikováno v: eNeuro
eNeuro, Society for Neuroscience, 2017, 4 (1), pp.ENEURO.0327-16.2017. ⟨10.1523/ENEURO.0327-16.2017⟩
eNeuro, 2017, 4 (1), pp.ENEURO.0327-16.2017. ⟨10.1523/ENEURO.0327-16.2017⟩

Visual Abstract
Serotonin (5-HT) neurotransmission in the brain relies on a widespread axon terminal network originating from the hindbrain raphe nuclei. These projections are topographically organized such that the dorsal (DR), and median raphe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919a8e93c1510b31bfc406d98f436b19
https://hal.archives-ouvertes.fr/hal-02559482

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PKA regulatory subunit 1A inactivating mutation induces serotonin signaling in primary pigmented nodular adrenal disease

Autor: Bruno Ragazzon, Isabelle Boutelet, Julien Wils, Marthe Rizk-Rabin, Estelle Louiset, Zakariae Bram, Marie-Christine Vantyghem, Rossella Libé, Sylvie Renouf, Constantine A. Stratakis, Eva Szarek, Céline Duparc, Dennis A. Carson, Antoine Martinez, Jacques Young, Hervé Lefebvre, Jérôme Bertherat

Publikováno v: JCI Insight
JCI Insight, American Society for Clinical Investigation, 2016, 1 (15), pp.e87958. ⟨10.1172/jci.insight.87958⟩
JCI Insight, 2016, 1 (15), pp.e87958. ⟨10.1172/jci.insight.87958⟩
JCI Insight, American Society for Clinical Investigation, 2016, 1 (15), ⟨10.1172/jci.insight.87958⟩

International audience; Primary pigmented nodular adrenocortical disease (PPNAD) is a rare cause of ACTH-independent hypercortisolism. The disease is primarily caused by germline mutations of the protein kinase A (PKA) regulatory subunit 1A (PRKAR1A)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54122e209af72f6b75250a8b64f8281e
https://hal.archives-ouvertes.fr/hal-02108040

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No human tryptophan hydroxylase-2 gene R441H mutation in a large cohort of psychiatric patients and control subjects

Autor: Catalina Betancur, Christopher Gillberg, Fabrice Jollant, Nader Perroud, Richard Delorme, Philippe Courtet, Patrick Baud, Michael Wagner, Guido Bondolfi, Stephan Ruhrmann, Jean-Michel Aubry, Hans-Juergen Grabe, Christelle M. Durand, Catherine Buresi, Thomas Bourgeron, Gilles Bertschy, Alain Malafosse, Gudrun Nygren, Marion Leboyer

Publikováno v: Biological Psychiatry
Biological Psychiatry, Elsevier, 2006, 60 (2), pp.202-3. ⟨10.1016/j.biopsych.2005.12.014⟩
Biological Psychiatry, 2006, 60 (2), pp.202-3. ⟨10.1016/j.biopsych.2005.12.014⟩

BACKGROUND: It was recently reported that a rare functional variant, R441H, in the human tryptophan hydroxylase-2 gene (hTPH2) could represent an important risk factor for unipolar major depression (UP) since it was originally found in 10% of UP pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22eac38739123384f004482ad71b322
https://www.hal.inserm.fr/inserm-00124742/document

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Tyrosine hydroxylase in the european eel (Anguilla anguilla): cDNA cloning, brain distribution, and phylogenetic analysis

Autor: Sylviane Boularand, Michèle Veron, Philippe Vernier, Nicole Faucon Biguet, Jean-Didier Vincent, Sylvie Dufour, B. Vidal, Jacques Mallet

Publikováno v: Journal of Neurochemistry
Journal of Neurochemistry, 1998, 71 (2), pp.460-470. ⟨10.1046/j.1471-4159.1998.71020460.x⟩

International audience; We report the isolation of a full-length eel tyrosine hydroxylase (TH) cDNA that is characterized by a long 3' untranslated region and by a diversity restricted to the 3' end owing to the differential use of three polyadenylat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d1b30abc43bcc6712a886e03c4ed82
https://pubmed.ncbi.nlm.nih.gov/9681435

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