Zobrazeno 1 - 10
of 34
pro vyhledávání: '"MESH: Transforming Growth Factor beta1"'
Autor:
Marie Maumus, Pauline Rozier, Florence Sabatier, Danièle Noël, Alexandre Thibault Jacques Maria, Christian Jorgensen, Claire Bony, Philippe Guilpain
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6837, p 6837 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, 2021, 22 (13), pp.6837. ⟨10.3390/ijms22136837⟩
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, 2021, 22 (13), pp.6837. ⟨10.3390/ijms22136837⟩
International audience; Systemic sclerosis (SSc) is a complex disorder resulting from dysregulated interactions between the three main pathophysiological axes: fibrosis, immune dysfunction, and vasculopathy, with no specific treatment available to da
Publikováno v:
Eye
Eye, Nature Publishing Group: Open Access Hybrid Model Option B, 2020, 34 (2), pp.232-240. ⟨10.1038/s41433-019-0684-8⟩
Eye (Lond)
Eye, Nature Publishing Group: Open Access Hybrid Model Option B, 2020, 34 (2), pp.232-240. ⟨10.1038/s41433-019-0684-8⟩
Eye (Lond)
Tissue healing is one of the mysteries of modern medicine. Healing involves complex processes and many cellular types, amongst which the myofibroblast plays a major role. In the eye, when needed, myofibroblasts can be found from the cornea to the ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d05b6a91439f57d47d0f9b7b45fef0
https://hal.archives-ouvertes.fr/hal-03269254
https://hal.archives-ouvertes.fr/hal-03269254
Autor:
Christian Dani, A. Remaury, Jean Galitzky, Y. Veeranagouda, A. Briot, Anne Bouloumié, David Estève, M. Didier, Pauline Decaunes, Séverine Ledoux, Nathalie Boulet, Alexia Zakaroff-Girard, C. Belles, Jean-Claude Guillemot
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, 2019, 10 (1), pp.2549. ⟨10.1038/s41467-019-09992-3⟩
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, 2019, 10 (1), pp.2549. ⟨10.1038/s41467-019-09992-3⟩
Human adipose tissue (hAT) is constituted of structural units termed lobules, the organization of which remains to be defined. Here we report that lobules are composed of two extracellular matrix compartments, i.e., septa and stroma, delineating nich
Autor:
Grégory Jouvion, Jennifer Dahan, Yann Nouët, Anne-Marie Cassard-Doulcier, Varun Khanna, Yu Wei, Thierry Tordjmann, Minou Adib-Conquy, Catherine Werts, Martine Fanton d'Andon, Florence Levillayer, Tian Xia, Marie-Annick Buendia, Ju Chen
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, 2017, 37 (10), pp.e00636-16. ⟨10.1128/MCB.00636-16⟩
Molecular and Cellular Biology, American Society for Microbiology, 2017, 37 (10), pp.e00636-16. ⟨10.1128/MCB.00636-16⟩
Molecular and Cellular Biology, 2017, 37 (10), pp.e00636-16. ⟨10.1128/MCB.00636-16⟩
Molecular and Cellular Biology, American Society for Microbiology, 2017, 37 (10), pp.e00636-16. ⟨10.1128/MCB.00636-16⟩
International audience; Transforming growth factor β1 (TGF-β1) is a master cytokine in many biological processes, including tissue homeostasis, epithelial-to-mesenchymal transition, and wound repair. Here, we report that four and a half LIM-only pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bfb2239ac2147d7b2763213df83801
https://hal-pasteur.archives-ouvertes.fr/pasteur-02572332/file/LIM_only_protein_FHL2_2017_Dahan.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-02572332/file/LIM_only_protein_FHL2_2017_Dahan.pdf
Autor:
Karim Boumediene, Nicolas Bigot, Elise Duval, Ikuyo Kou, Sylvain Leclercq, Philippe Galéra, Magalie Hervieu, Catherine Baugé
Publikováno v:
Molecular Medicine
Molecular Medicine, Feinstein Institute for Medical Research, 2010, 17 (7-8), pp.816-23. ⟨10.2119/molmed.2011.00052⟩
Molecular Medicine, Feinstein Institute for Medical Research, 2010, 17 (7-8), pp.816-23. 〈10.2119/molmed.2011.00052〉
Molecular Medicine, Feinstein Institute for Medical Research, 2010, 17 (7-8), pp.816-23. ⟨10.2119/molmed.2011.00052⟩
Molecular Medicine, Feinstein Institute for Medical Research, 2010, 17 (7-8), pp.816-23. 〈10.2119/molmed.2011.00052〉
International audience; A significant association between a polymorphism in the D repeat of the gene encoding asporin and osteoarthritis, the most frequent of articular diseases, has been recently reported. The goal of the present study was to invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67579252e0605e13bc06a938333d353e
http://arxiv.org/abs/1505.06921
http://arxiv.org/abs/1505.06921
Lethal Effect of CD3-Specific Antibody in Mice Deficient in TGF-β1 by Uncontrolled Flu-Like Syndrome
Autor:
Sylvain Perruche, Pin Zhang, Takashi Maruyama, Philippe Saas, Wanjun Chen, Jeffrey A. Bluestone
Publikováno v:
Journal of Immunology
Journal of Immunology, 2009, 183 (2), pp.953-61. ⟨10.4049/jimmunol.0804076⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2009, 183 (2), pp.953-61. ⟨10.4049/jimmunol.0804076⟩
Journal of Immunology, 2009, 183 (2), pp.953-61. ⟨10.4049/jimmunol.0804076⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2009, 183 (2), pp.953-61. ⟨10.4049/jimmunol.0804076⟩
CD3-specific Ab therapy results in a transient, self-limiting, cytokine-associated, flu-like syndrome in experimental animals and in patients, but the underlying mechanism for this spontaneous resolution remains elusive. By using an in vivo model of
Autor:
Nathalie Pizzinat, Mansour Akkiki, Angelo Parini, Marie-Hélène Seguelas, Samiye Yabanoglu, Jeanne Mialet-Perez
Publikováno v:
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, 2009, 46 (4), pp.518-25. ⟨10.1016/j.yjmcc.2008.12.019⟩
Journal of Molecular and Cellular Cardiology, 2009, 46 (4), pp.518-25. ⟨10.1016/j.yjmcc.2008.12.019⟩
Platelet activation occurs in different acute and chronic heart diseases including myocardial infarction, obstructive hypertrophic cardiomyopathy and valve stenosis. Recent studies suggested that some factors secreted by activated platelets may parti
Autor:
Barbara Garmy-Susini, Cédric Filipe, Bertrand Calippe, Alexia Schambourg, François Tercé, Pierre Gourdy, Victorine Douin-Echinard, Jean-François Arnal, Francis Bayard
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2007, 27 (10), pp.2214-21. ⟨10.1161/ATVBAHA.107.150300⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, 2007, 27 (10), pp.2214-21. ⟨10.1161/ATVBAHA.107.150300⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2007, 27 (10), pp.2214-21. ⟨10.1161/ATVBAHA.107.150300⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, 2007, 27 (10), pp.2214-21. ⟨10.1161/ATVBAHA.107.150300⟩
Objective— Whereas estradiol prevents fatty streak deposit in immunocompetent apoE −/− or LDLr −/− mice, it is totally ineffective in immunodeficient mice, underlining the key role of immunoinflammation in this effect. In the present work,
Autor:
Marie-Lise Maddelein, Virginie Garcia, Dimitri Pchejetski, Leyre Brizuela, Marie-Bernadette Delisle, Marie-Françoise Altié, A. Gomez-Brouchet, Olivier Cuvillier
Publikováno v:
Molecular Pharmacology
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2007, 72 (2), pp.341-349. ⟨10.1124/mol.106.033738⟩
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2007, 72 (2), pp.341-349. ⟨10.1124/mol.106.033738⟩
International audience; We examined the role of sphingosine kinase-1 (SphK1), a critical regulator of the ceramide/sphingosine 1-phosphate (S1P) biostat, in the regulation of death and survival of SH-SY5Y neuroblastoma cells in response to amyloid be
Autor:
Annegret Gerber, Vera Preller, Sabine Wrenger, Janine Tadje, Didier Marguet, Klaus Neubert, Uwe Lendeckel, Burkhart Schraven, Siegfried Ansorge, Jürgen Faust, Mauro Togni, Stefan Brocke, Christoph Röcken, Dirk Reinhold, Roland Martin
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2007, 178 (7), pp.4632-40
Journal of Immunology, 2007, 178 (7), pp.4632-40
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2007, 178 (7), pp.4632-40
Journal of Immunology, 2007, 178 (7), pp.4632-40
The T cell marker CD26/dipeptidyl peptidase (DP) IV is associated with an effector phenotype and markedly elevated in the human CNS disorder multiple sclerosis. However, little is known about the in vivo role of CD26/DP IV in health and disease, and