CXCR3 antagonism of SDF-1(5-67) restores trabecular function and prevents retinal neurodegeneration in a rat model of ocular hypertension

Autor: William Rostène, Julie Frugier, Françoise Baleux, David Godefroy, Isabelle Célérier, Serge Picaud, Françoise Brignole-Baudouin, Julie Degardin, Jeffrey K. Harrison, Christophe Baudouin, José Sahel, Alexandre Denoyer

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7 (6), pp.e37873. ⟨10.1371/journal.pone.0037873⟩
PLoS ONE, Public Library of Science, 2012, 7 (6), pp.e37873. 〈10.1371/journal.pone.0037873〉
PLoS ONE, Vol 7, Iss 6, p e37873 (2012)
PLoS ONE, 2012, 7 (6), pp.e37873. ⟨10.1371/journal.pone.0037873⟩

International audience; Glaucoma, the most common cause of irreversible blindness, is a neuropathy commonly initiated by pathological ocular hypertension due to unknown mechanisms of trabecular meshwork degeneration. Current antiglaucoma therapy does

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f2117383dc58fb64ab823fe3a14537
https://pubmed.ncbi.nlm.nih.gov/22675496