TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis

Autor: Izabela A. Rodenhuis-Zybert, Vinit Upasani, Bram M. ter Ellen, Mariana Ruiz-Silva, Rithy Choeung, Jill Moser, Mindaugas Pauzuolis, Denis R. St. Laurent, Tineke Cantaert, Philippe Dussart, José Alberto Aguilar-Briseño, Sothy Heng, Jolanda M. Smit

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.3177. ⟨10.1038/s41467-020-16849-7⟩
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 11(1):3177. Nature Publishing Group

Vascular permeability and plasma leakage are immune-pathologies of severe dengue virus (DENV) infection, but the mechanisms underlying the exacerbated inflammation during DENV pathogenesis are unclear. Here, we demonstrate that TLR2, together with it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208ffd5bdf01936c1e26cb9d9b748d7d
https://hal-riip.archives-ouvertes.fr/pasteur-03221719