Clinical Deterioration Following Middle Cerebral Artery Hemodynamic Changes after Intravenous Thrombolysis for Acute Ischemic Stroke

Autor: Yves Samson, Marlene Alonso-Juarez, José Fidel Baizabal-Carvallo

Publikováno v: Journal of Stroke and Cerebrovascular Diseases
Journal of Stroke and Cerebrovascular Diseases, 2014, 23 (2), pp.254-8

International audience; Little information exists regarding what occurs in the affected artery in the days after acute ischemic stroke and its impact in the outcome. We sought to determine the hemodynamic evolution and correlated this evoution with c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae08976287e7dfe6c99cf991ad248fde
https://doi.org/10.1016/j.jstrokecerebrovasdis.2013.01.015

Fibrinolysis for patients with intermediate-risk pulmonary embolism

Autor: Sebastian Schellong, Mustapha Sebbane, Thierry Danays, Samuel Z. Goldhaber, Guy Meyer, Irene M. Lang, Cecilia Becattini, Eric Vicaut, Francis Couturaud, Christian Kupatt, Bożena Sobkowicz, Adam Torbicki, Claudia Dellas, Franck Verschuren, Erich Bluhmki, Hélène Bouvaist, Abstr Act, Nicolas Meneveau, Branislav Stefanovic, Benjamin Brenner, Annette Geibel, Piotr Pruszczyk, Mareike Lankeit, Jan Beyer-Westendorf, Ana Franca, Nils Kucher, Klaus Empen, David Jiménez, Matija Kozak, Nazzareno Galiè, Holger Thiele, Antoniu Petris, Giancarlo Agnelli, Gerard Pacouret, Aldo Salvi, Stavros Konstantinides, Matteo Rugolotto, Massimiliano Palazzini

Publikováno v: Meyer, Guy; Vicaut, Eric; Danays, Thierry; Agnelli, Giancarlo; Becattini, Cecilia; Beyer-Westendorf, Jan; Bluhmki, Erich; Bouvaist, Helene; Brenner, Benjamin; Couturaud, Francis; Dellas, Claudia; Empen, Klaus; Franca, Ana; Galiè, Nazzareno; Geibel, Annette; Goldhaber, Samuel Z.; Jimenez, David; Kozak, Matija; Kupatt, Christian; Kucher, Nils; ... (2014). Fibrinolysis for patients with intermediate-risk pulmonary embolism. New England journal of medicine NEJM, 370(15), pp. 1402-1411. Massachusetts Medical Society MMS 10.1056/NEJMoa1302097
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New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2014, 370 (15), pp.1402-11. 〈10.1056/NEJMoa1302097〉
New England Journal of Medicine, Massachusetts Medical Society, 2014, 370 (15), pp.1402-11. ⟨10.1056/NEJMoa1302097⟩

International audience; BACKGROUND: The role of fibrinolytic therapy in patients with intermediate-risk pulmonary embolism is controversial. METHODS: In a randomized, double-blind trial, we compared tenecteplase plus heparin with placebo plus heparin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8884407c666ea6ff838038ea707349a
https://pubmed.ncbi.nlm.nih.gov/25594091

Cloning and Expression of Functional Full-Length Human Tissue Plasminogen Activator in Pichia pastoris

Autor: Fereidoun Mahboudi, Davami Fatemeh, Barkhordari Farzaneh, Hemayatkar Mahdi, Keivan Majidzadeh-A, Vahid Khalaj, Adeli Ahmad

Publikováno v: Applied Biochemistry and Biotechnology
Applied Biochemistry and Biotechnology, Humana Press, 2010, 162 (7), pp.2037-48. ⟨10.1007/s12010-010-8979-z⟩

International audience; Human tissue plasminogen activator (t-PA) plays a pivotal role in the treatment of acute myocardial infarction, ischemic stroke, and deep vein thrombosis. It has the benefit of generating no adverse effects such as fibrinogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5233656395b8a8970d629d54887113e1
https://doi.org/10.1007/s12010-010-8979-z

BDNF-TrkB signaling through Erk1/2MAPK phosphorylation mediates the enhancement of fear memory induced by glucocorticoids

Autor: P.V. Piazza, Françoise Rougé-Pont, A. Y. Le Roux, N Kaouane, J-M Revest, Aline Desmedt, Monique Vallée, Valérie Roullot-Lacarrière, F Tronche, Fernando Kasanetz

Publikováno v: Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2014, 19 (9), pp.1001-1009. ⟨10.1038/mp.2013.134⟩

International audience; Activation of glucocorticoid receptors (GR) by glucocorticoid hormones (GC) enhances contextual fear memories through the activation of the Erk1/2(MAPK) signaling pathway. However, the molecular mechanism mediating this effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad88ff5dd473f49b2f6ae7ffa003fed6
https://hal.archives-ouvertes.fr/hal-02323699

Bulk-solvent correction in large macromolecular structures

Autor: B. Rees, Marat Yusupov, Lasse Jenner

Publikováno v: Acta Crystallographica Section D: Biological Crystallography
Acta Crystallographica Section D: Biological Crystallography, International Union of Crystallography, 2005, 61 (Pt 9), pp.1299-301. ⟨10.1107/S0907444905019591⟩

International audience; The estimation of the bulk-solvent contribution to the diffraction of a macromolecular crystal makes use of a solvent mask which delimits the bulk-solvent regions in the crystal. It is shown that the way this mask is usually d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d228802757000346cc32f25ed5a1974
https://doi.org/10.1107/s0907444905019591