Výsledky vyhledávání - "MESH: Tight Junctions / metabolism"

The Actin-Based Motor Myosin Vb Is Crucial to Maintain Epidermal Barrier Integrity

Autor: Guy Serre, Marie Reynier, Alain Moga, Corinne Leprince, Sophie Allart, Dominique Goudounèche, Michel Simon

Publikováno v: Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2019, 139 (7), pp.1430-1438. ⟨10.1016/j.jid.2018.12.021⟩
Journal of Investigative Dermatology, 2019, 139 (7), pp.1430-1438. ⟨10.1016/j.jid.2018.12.021⟩

International audience; Myosin Vb (Myo5b) is an unconventional myosin involved in the actin-dependent transport and tethering of intracellular organelles. In the epidermis, granular keratinocytes accumulate cytoplasmic lamellar bodies (LBs), secretor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b23279e57f8e5cb9731c489548ae9e
https://doi.org/10.1016/j.jid.2018.12.021

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Toxoplasma Parasite Twisting Motion Mechanically Induces Host Cell Membrane Fission to Complete Invasion within a Protective Vacuole

Autor: Martial Balland, Bastien Touquet, Mateusz Biesaga, Georgios Pavlou, Isabelle Tardieux, Vanessa Lagal, Alexandre Dufour, Mohamed-Ali Hakimi

Publikováno v: Cell Host and Microbe
Cell Host and Microbe, 2018, 24 (1), pp.81-96.e5. ⟨10.1016/j.chom.2018.06.003⟩
Cell Host and Microbe, Elsevier, 2018, 24 (1), pp.81-96.e5. ⟨10.1016/j.chom.2018.06.003⟩

International audience; To invade cells, the parasite Toxoplasma gondii injects a multi-unit nanodevice into the target cell plasma membrane (PM). The core nanodevice, which is composed of the RhOptry Neck (RON) protein complex, connects Toxoplasma a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9a7422ea16110b1f986c6077d4407b
https://www.hal.inserm.fr/inserm-02440390

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Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry

Autor: Sandrine Belouzard, Jens Bukh, Lucie Fénéant, Priscille Brodin, Yves Rouillé, Jean Dubuisson, Laura Riva, Thomas F. Baumert, Alexandre Vandeputte, François Helle, Jannick Prentoe, Laurent L'homme, Laurence Cocquerel, Charles-Henry Gattolliat, Ok-Ryul Song, Tarik Asselah

Publikováno v: Journal of Virology
Journal of Virology, 2018, 92 (10), pp.e01982-17. ⟨10.1128/JVI.01982-17⟩
Journal of Virology, American Society for Microbiology, 2018, 92 (10), pp.e01982-17. ⟨10.1128/JVI.01982-17⟩

Hepatitis C virus (HCV) infection causes 500,000 deaths annually, in association with end-stage liver diseases. Investigations of the HCV life cycle have widened the knowledge of virology, and here we discovered that two piperazinylbenzenesulfonamide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eede9d22a44a24224a0d9eb270333e63
https://pubmed.ncbi.nlm.nih.gov/29491159

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Skin barrier in atopic dermatitis

Autor: Sanja Kezic, Ivone Jakasa, Michel Simon, M.A. Middelkamp‐Hup, Natalija Novak, Stephan Weidinger, Jackob M Jungersted, Johanna M Brandner

Publikováno v: Frontiers in Bioscience
Frontiers in Bioscience, Frontiers in Bioscience, 2014, 19 (3), pp.542-556. ⟨10.2741/4225⟩
FRONTIERS IN BIOSCIENCE-LANDMARK, 19, 542-556. Frontiers in Bioscience

International audience; The skin represents the largest organ of the body and provides a vital interface between the body and the environment. Hereditary and acquired alterations of structural proteins and lipids of the stratum corneum and epidermal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f68f9bf8c3863ac23cfbac226c5977
https://pubmed.ncbi.nlm.nih.gov/24389202

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