Zobrazeno 1 - 6
of 6
pro vyhledávání: '"MESH: Thymidylate Synthase"'
Autor:
Hannu Myllykallio, Marten H. Vos, Sergey P. Laptenok, Ursula Liebl, Latifa Bouzhir-Sima, Jean-Christophe Lambry
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013, 110 (22), pp.8924-8929. ⟨10.1073/pnas.1218729110⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2013, 110 (22), pp.8924-8929. ⟨10.1073/pnas.1218729110⟩
In many bacteria the flavoenzyme thymidylate synthase ThyX produces the DNA nucleotide deoxythymidine monophosphate from dUMP, using methylenetetrahydrofolate as carbon donor and NADPH as hydride donor. Because all three substrates bind in close prox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d053cb02a63183bcee170f785db079
https://hal-polytechnique.archives-ouvertes.fr/hal-00942352
https://hal-polytechnique.archives-ouvertes.fr/hal-00942352
Autor:
Slah Ouerhani, Mohamed Cherif, Mohamed Sfaxi, Najla Stambouli, Amel Benammar Elgaaied, Mohamed Chebil, Mohamed Riadh Ben Slama, Kamel Rouissi, Raja Marrakchi
Publikováno v:
Bulletin du Cancer
Bulletin du Cancer, John Libbey Eurotext, 2011, 98 (2), pp.E1-10. ⟨10.1684/bdc.2011.1312⟩
Bulletin du Cancer, John Libbey Eurotext, 2011, 98 (2), pp.E1-10. ⟨10.1684/bdc.2011.1312⟩
International audience; Folates are the common sources of DNA synthesis and methylation. Cigarette smoking and genetic susceptibility of folate enzymes are two suspected factors most closely associated with bladder cancer development. This study soug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a6ee4f2669afd6379e884f882a4647
https://hal-riip.archives-ouvertes.fr/pasteur-00714007
https://hal-riip.archives-ouvertes.fr/pasteur-00714007
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2008, 105 (29), pp.9948-52. ⟨10.1073/pnas.0801356105⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2008, 105 (29), pp.9948-52. ⟨10.1073/pnas.0801356105⟩
International audience; We have investigated the hitherto unexplored possibility that differences in the catalytic efficiencies of thymidylate synthases ThyX and ThyA, enzymes that produce the essential DNA precursor dTMP, have influenced prokaryotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c208a8c072669b19a3e3cb94a17ab6c2
https://hal.archives-ouvertes.fr/hal-00353456
https://hal.archives-ouvertes.fr/hal-00353456
Publikováno v:
Molecular Microbiology
Molecular Microbiology, Wiley, 2006, 59, pp.317-25
Molecular Microbiology, Wiley, 2006, 59 (1), pp.317-25. ⟨10.1111/j.1365-2958.2005.04936.x⟩
Molecular Microbiology, Wiley, 2006, 59, pp.317-25
Molecular Microbiology, Wiley, 2006, 59 (1), pp.317-25. ⟨10.1111/j.1365-2958.2005.04936.x⟩
Analysis of the complete genome indicates that insertion sequences (ISs) are abundant in the radio-resistant bacterium Deinococcus radiodurans. By developing a forward mutagenesis assay to detect any inactivation events in D. radiodurans, we found th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a8573428b8aa08493f873d36ae48aa
https://hal.archives-ouvertes.fr/hal-00079728
https://hal.archives-ouvertes.fr/hal-00079728
Autor:
Nimol Khim, Socheat Doung, Odile Puijalon, Christiane Bouchier, Sandra Incardona, Ronan Jambou, Eric Legrand, Pharath Lim, Marie-Thérèse Ekala, Thierry Fandeur
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2005, 49 (8), pp.3147-3152
Antimicrobial Agents and Chemotherapy, 2005, 49 (8), pp.3147-52. ⟨10.1128/AAC.49.8.3147-3152.2005⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2005, 49 (8), pp.3147-52. ⟨10.1128/AAC.49.8.3147-3152.2005⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2005, 49 (8), pp.3147-3152
Antimicrobial Agents and Chemotherapy, 2005, 49 (8), pp.3147-52. ⟨10.1128/AAC.49.8.3147-3152.2005⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2005, 49 (8), pp.3147-52. ⟨10.1128/AAC.49.8.3147-3152.2005⟩
Cambodia is located in an area of resistance to multiple antimalarials and has been the first country to implement the systematic use of an artesunate-mefloquine combination as first-line treatment for Plasmodium falciparum malaria. Little is known,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6d5ba588bd00af7a87521dac044885
https://hal.inrae.fr/hal-02672125
https://hal.inrae.fr/hal-02672125
Publikováno v:
Nature
Nature, Nature Publishing Group, 1992, 357 (6378), pp.508-513. ⟨10.1038/357508a0⟩
Nature, Nature Publishing Group, 1992, 357 (6378), pp.508-513. ⟨10.1038/357508a0⟩
International audience; Most genes involved in DNA replication in the yeast Saccharomyces cerevisiae are transcribed transiently during late G1 as cells become committed to a new cell cycle at Start. Their promoters all contain one or more versions o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2a6a43af5dbf511ffcdde8551d4773
https://pubmed.ncbi.nlm.nih.gov/1608451
https://pubmed.ncbi.nlm.nih.gov/1608451
