Zobrazeno 1 - 10 of 53 pro vyhledávání: '"MESH: Th1 Cells"'
1
Immunization with synthetic SARS-CoV-2 S glycoprotein virus-like particles protects macaques from infection
Autor: Isabelle Bally, Judith A. Burger, Rogier W. Sanders, M. Buisson, Wesley Gros, Pascal Poignard, Axelle Amen, Roger Le Grand, Daphna Fenel, Francis Relouzat, Guy Schoehn, Camille Bouillier, Vanessa Contreras, Nicole M. Thielens, Julien Lemaitre, Franck Fieschi, Guidenn Sulbaran, Sylvie van der Werf, Anne-Sophie Gallouet, Nathalie Dereuddre-Bosquet, Winfried Weissenhorn, Romain Marlin, Michel Thépaut, Thibaut Naninck, Delphine Guilligay, Sebastian Dergan Dylon, Marit J. van Gils, Pauline Maisonnasse, Meliawati Poniman
Publikováno v: Cell Reports Medicine
Cell Reports Medicine, 2022, 3 (2), pp.100528. ⟨10.1016/j.xcrm.2022.100528⟩
Cell Reports Medicine, 3(2):100528. Cell Press
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused an ongoing global health crisis. Here, we present as a vaccine candidate synthetic SARS-CoV-2 spike (S) glycoprotein-coated lipid vesicles that resemble virus-like p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b4da894dec1ba3c940c33c50f57284
https://doi.org/10.1016/j.xcrm.2022.100528
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2
MicroRNAs Associated With a Good Prognosis of Acute Myeloid Leukemia and Their Effect on Macrophage Polarization
Autor: Alexandra Neaga, Cristina Bagacean, Adrian Tempescul, Laura Jimbu, Oana Mesaros, Cristina Blag, Ciprian Tomuleasa, Corina Bocsan, Mihaela Gaman, Mihnea Zdrenghea
Publikováno v: Frontiers in Immunology
Frontiers in Immunology, 2021, 11, pp.582915. ⟨10.3389/fimmu.2020.582915⟩
Frontiers in Immunology, Vol 11 (2021)
International audience; Acute myeloid leukemia (AML) is an aggressive myeloid malignancy with poor outcomes despite very intensive therapeutic approaches. For the majority of patients which are unfit and treated less intensively, the prognosis is eve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05d116c053505ae2ddbef303a40fb51
https://doi.org/10.3389/fimmu.2020.582915
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3
Increased CXCR3+ T Cells Impairs Recruitment of T-Helper Type 17 Cells via Interferon γ and Interleukin 18 in the Small Intestine Mucosa During Treated HIV-1 Infection
Autor: Nicolas Carrere, Jacques Izopet, Bertrand Suc, Claire Loiseau, Michelle Cazabat, Pierre Delobel, Mary Requena, Manon Nayrac, Laurent Alric, M Mavigner, A L Iscache
Publikováno v: Journal of Infectious Diseases
Journal of Infectious Diseases, 2019, 220 (5), pp.830-840. ⟨10.1093/infdis/jiz123⟩
Journal of Infectious Diseases, Oxford University Press (OUP), 2019, 220 (5), pp.830-840. ⟨10.1093/infdis/jiz123⟩
The restoration of CD4+ T cells, especially T-helper type 17 (Th17) cells, remains incomplete in the gut mucosa of most human immunodeficiency virus type 1 (HIV-1)–infected individuals despite sustained antiretroviral therapy (ART). Herein, we repo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf1141fb4f0f9aada7cab65629d072a
https://ut3-toulouseinp.hal.science/hal-03355691
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4
HIV Controllers Have Low Inflammation Associated with a Strong HIV-Specific Immune Response in Blood
Autor: Christine Lacabaratz, Jean-Daniel Lelièvre, Pierre Versmisse, Yves Levy, Hakim Hocini, Emile Foucat, Pascaline Tisserand, Rodolphe Thiébaut, Asier Sáez-Cirión, Henri Bonnabau, Olivier Lambotte, Cécile Lefebvre
Publikováno v: Journal of Virology
Journal of Virology, 2019, 93 (10), pp.e01690-18. ⟨10.1128/JVI.01690-18⟩
Journal of Virology, American Society for Microbiology, 2019, 93 (10), pp.e01690-18. ⟨10.1128/JVI.01690-18⟩
International audience; HIV controllers (HIC) maintain control of HIV replication without combined antiretroviral treatment (cART). The mechanisms leading to virus control are not fully known. We used gene expression and cellular analyses to compare
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7de45cc74ccdd814a61a22dc5750227
https://hal-pasteur.archives-ouvertes.fr/pasteur-02549956/file/181654_2_merged_1549975810.pdf
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5
Treatment with synthetic lipophilic tyrosyl ester controls Leishmania major infection by reducing parasite load in BALB/c mice
Autor: Fatma Z. Guerfali, Hanène Attia, Youssef Gargouri, Pablo A. Leon Martinez, Ghada Mkannez, Aymen Bali, Dhafer Laouini, Imen Aissa, Rabiaa M. Sghaier
Publikováno v: Parasitology
Parasitology, Cambridge University Press (CUP), 2016, 143 (12), pp.1615-1620. ⟨10.1017/S0031182016001086⟩
SUMMARYSynthesized lipophilic tyrosyl ester derivatives with increasing lipophilicity were effective against Leishmania (L.) major and Leishmania infantum species in vitro. These findings prompted us to test in vivo leishmanicidal properties of these
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bc2abccdcddddc96eac44eca020091
https://doi.org/10.1017/s0031182016001086
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6
The role of Eomes in human CD4 T cell differentiation: A question of context
Autor: Thierry Walzer, Anne Dejean, Emeline Joulia
Publikováno v: European Journal of Immunology
European Journal of Immunology, 2019, 49 (1), pp.38-41. ⟨10.1002/eji.201848000⟩
International audience; Eomesodermin (Eomes) is a transcription factor (TF) of the T-box family closely related to T-bet known for its role in CD8 T cell and natural killer cell differentiation. However, the role of Eomes in CD4 T-cell differentiatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567740c5f677dc064169d2d12625b057
https://pubmed.ncbi.nlm.nih.gov/30431161
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7
The Histone Methyltransferase SETDB1 Controls T Helper Cell Lineage Integrity by Repressing Endogenous Retroviruses
Autor: Sebastian Amigorena, Paola Romagnoli, Agathe Malbec, Véronique Adoue, Joost P.M. van Meerwijk, Olivier Joffre, Joanna Fourquet, Bénédicte Binet
Publikováno v: Immunity
Immunity, 2019, 50 (3), pp.629-644.e8. ⟨10.1016/j.immuni.2019.01.003⟩
Immunity, Elsevier, 2019, 50 (3), pp.629-644.e8. ⟨10.1016/j.immuni.2019.01.003⟩
International audience; Upon activation, naive CD4+ T cells differentiate into distinct T cell subsets via processes reliant on epigenetically regulated, lineage-specific developmental programs. Here, we examined the function of the histone methyltra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a10471dc12184df5235014b4cd16d9
https://pubmed.ncbi.nlm.nih.gov/30893582
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8
Long-Lasting Effects of BCG Vaccination on Both Heterologous Th1/Th17 Responses and Innate Trained Immunity
Autor: Mihai G. Netea, Peter Aaby, Jessica Quintin, Joke van Loenhout, Johanneke Kleinnijenhuis, Jos W. M. van der Meer, Leo A. B. Joosten, Christine Stabell Benn, Frank Preijers, Reinout van Crevel, Cor Jacobs, Ramnik J. Xavier
Publikováno v: Kleinnijenhuis, J, Quintin, J, Preijers, F, Benn, C S, Joosten, L A B, Jacobs, C, van Loenhout, J, Xavier, R J, Aaby, P, van der Meer, J W M, van Crevel, R & Netea, M G 2013, ' Long-Lasting Effects of BCG Vaccination on Both Heterologous Th1/Th17 Responses and Innate Trained Immunity ', Journal of Innate Immunity, vol. 37, no. 9, pp. 1041–1045 . https://doi.org/10.1159/000355628
Journal of Innate Immunity
Journal of Innate Immunity, Karger, 2014, 6 (2), pp.152-158. ⟨10.1159/000355628⟩
Journal of Innate Immunity, 6, 2, pp. 152-8
Journal of Innate Immunity, 6, 152-8
Contains fulltext : 138552.pdf (Publisher’s version ) (Open Access) We have recently shown that BCG (Bacillus Calmette-Guerin) vaccination in healthy volunteers induces epigenetic reprogramming of monocytes, leading to increased cytokine production
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11106bbbab3561efbf3a4d42ce73ddb5
https://hdl.handle.net/2066/138552
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9
Influence of heat stress on human monocyte-derived dendritic cell functions with immunotherapeutic potential for antitumor vaccines
Autor: Pierre Formstecher, Thierry Velu, Audrey Lasek, Anne Sophie Hatzfeld-Charbonnier, Laurent Mortier, Laurent Castera, Philippe Gosset, Philippe Marchetti
Publikováno v: Journal of Leukocyte Biology
Journal of Leukocyte Biology, Society for Leukocyte Biology, 2007, 81 (5), pp.1179-1187. ⟨10.1189/jlb.0506347⟩
Journal of Leukocyte Biology, 2007, 81 (5), pp.1179-1187. ⟨10.1189/jlb.0506347⟩
Mild heat stress can modulate the activities of immune cells, including dendritic cells (DC) and theoretically, would constitute an innovative approach capable of enhancing the antitumor functions of DC. Therefore, we tested the effects of mild heat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801e0ec17255c9aa9e798911417a2ecf
https://doi.org/10.1189/jlb.0506347
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10
A comparative study on intra-articular versus systemic gene electrotransfer in experimental arthritis
Autor: Christian Jorgensen, Florence Apparailly, Daniel Scherman, Pascal Bigey, H. Rhinn, Danièle Noël, Pascale Louis-Plence, Maroun Khoury
Publikováno v: The Journal of Gene Medicine
The Journal of Gene Medicine, Wiley, 2006, 8 (8), pp.1027-36. ⟨10.1002/jgm.922⟩
The Journal of Gene Medicine, 2006, 8 (8), pp.1027-36. ⟨10.1002/jgm.922⟩
The Journal of Gene Medicine, Wiley, 2006, 8 (8), pp.1027-36. 〈10.1002/jgm.922〉
Background Electric pulse mediated gene transfer has been applied successfully in vivo for increasing naked DNA administration in various tissues. To achieve non-viral gene transfer into arthritic joint tissue, we investigated the use of electrotrans
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fb8cb45b5b35d19e1cfd80a89b474d
https://doi.org/10.1002/jgm.922
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