Survival response-linked Pyk2 activation during potassium depletion-induced apoptosis of cerebellar granule neurons

Autor: Béatrice Blot, Flavie Strappazzon, Rémy Sadoul, Sakina Torch, Yaël Trioulier, Jean Marc Verna

Publikováno v: Molecular and Cellular Neuroscience
Molecular and Cellular Neuroscience, Elsevier, 2007, 34 (3), pp.355-65. ⟨10.1016/j.mcn.2006.11.012⟩
Molecular and Cellular Neuroscience, 2007, 34 (3), pp.355-65. ⟨10.1016/j.mcn.2006.11.012⟩

International audience; Numerous extracellular stimuli trigger trans-autophosphorylation at Tyr402 of Pyk2, inducing its activation. Pyk2 is a key mediator of several signaling pathways and has been implicated in apoptosis induced by specific stress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30abbd5bcecc51395f16569df96163c5
https://doi.org/10.1016/j.mcn.2006.11.012

1-methyl-4-phenylpyridinium neurotoxicity is attenuated by adenoviral gene transfer of human Cu/Zn superoxide dismutase

Autor: Philippe Horellou, Jacques Mallet, Martine Barkats, Stéphanie Millecamps, Philippe Colin, Nicole Faucon-Biguet

Publikováno v: Journal of Neuroscience Research
Journal of Neuroscience Research, 2006, 83 (2), pp.233-42. ⟨10.1002/jnr.20696⟩
Journal of Neuroscience Research, Wiley, 2006, 83 (2), pp.233-42. ⟨10.1002/jnr.20696⟩

Oxidative stress has been suggested to be an important mediator of dopaminergic cell death in Parkinson's disease (PD). We investigated the neuroprotective potential of Cu/Zn superoxide dismutase (SOD1) overexpression in the rat substantia nigra (SN)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6140ba666f5867b16e153b38198949
https://doi.org/10.1002/jnr.20696

D-Maurocalcine, a pharmacologically inert efficient cell-penetrating peptide analogue

Autor: Poillot, Cathy, Dridi, Kaouthar, Bichraoui, Hicham, Pêcher, Julien, Alphonse, Sébastien, Douzi, Badreddine, Ronjat, Michel, Darbon, Hervé, De Waard, Michel

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2010, 285 (44), pp.34168-80. ⟨10.1074/jbc.M110.104919⟩

International audience; Maurocalcine has been the first demonstrated animal toxin acting as a cell-penetrating peptide. Although it possesses competitive advantages, its use as a cell-penetrating peptide (CPP) requires that analogues be developed tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d1993a207aec82df415748d3ac91b9bb
https://www.hal.inserm.fr/inserm-00587800/file/inserm-00587800_edited.pdf

Cationic solid lipid nanoparticles loaded by cysteine proteinase genes as a novel anti-leishmaniasis DNA vaccine delivery system: characterization and in vitro evaluations

Autor: Alireza Vatanara, Abdolhossein Rouholamini Najafabadi, Elham Gholami, Sima Rafati, Delaram Doroud, Rouhollah Vahabpour, Farnaz Zahedifard

Publikováno v: Journal of Pharmacy and Pharmaceutical Sciences
Journal of Pharmacy and Pharmaceutical Sciences, Canadian Society for Pharmaceutical Sciences, 2010, 13 (3), pp.320-335. ⟨10.18433/J3R30T⟩
Journal of Controlled Release
Journal of Controlled Release, Elsevier, 2010, 148 (1), pp.e105-106. ⟨10.1016/j.jconrel.2010.07.079⟩
Scopus-Elsevier
Journal of Pharmacy & Pharmaceutical Sciences, Vol 13, Iss 3 (2010)

Purpose: Leishmaniasis is a major health problem in many tropical and sub-tropical countries and development of a safe and easily-available vaccine has high priority. Although several antigens potentially capable of inducing protective immunity have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4142d8acea44dc441c11d2988ab08b4
https://hal-riip.archives-ouvertes.fr/pasteur-00786994

Biochemical, genetic and molecular characterization of new respiratory-deficient mutants inChlamydomonas reinhardtii

Autor: Colleaux, Laurence, Dorthu, M, Remy, R, Michel-Wolwertz, R, Colleaux, C, Breyer, D, Beckers, C, Englebert, S, Duyckaerts, C, Sluse, F, Matagne, R

Publikováno v: Plant Molecular Biology
Plant Molecular Biology, Springer Verlag (Germany), 1992, 18 (4), pp.759-72

International audience; Eight respiratory-deficient mutants of Chlamydomonas reinhardtii have been isolated after mutagenic treatment with acriflavine or ethidium bromide. They are characterized by their inability to grow or their very reduced growth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51678f736388e2285ef4d20c9cb057a
https://doi.org/10.1007/bf00020017