ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription

Autor: Richard Treisman, Stuart Horswell, Aengus Stewart, Gavin Kelly, Phil East, Francesco Gualdrini, Nik Matthews, Cyril Esnault

Publikováno v: Molecular Cell
Molecular Cell, Elsevier, 2017, 65 (6), pp.1081-1095.e5. ⟨10.1016/j.molcel.2017.02.005⟩

Summary We investigated the relationship among ERK signaling, histone modifications, and transcription factor activity, focusing on the ERK-regulated ternary complex factor family of SRF partner proteins. In MEFs, activation of ERK by TPA stimulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5fe23111a617313cae3aea01ae42c5
https://hal.archives-ouvertes.fr/hal-03022260

Phorbol ester-modulation of estrogenic genomic effects triggered by the environmental contaminant benzanthracene

Autor: Elise Kolasa, Noémie Houlbert, Olivier Fardel, Patrick Balaguer

Publikováno v: Toxicology in Vitro
Toxicology in Vitro, Elsevier, 2012, 26 (6), pp.807-16. ⟨10.1016/j.tiv.2012.05.006⟩
Toxicology in Vitro, 2012, 26 (6), pp.807-16. ⟨10.1016/j.tiv.2012.05.006⟩

International audience; Aryl hydrocarbon receptor-dependent genomic effects of environmental polycyclic aromatic hydrocarbons (PAHs) have been shown to be modulated by non-genomic protein kinase C (PKC)-related pathways. The present study was designe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc819d853384ee2f51fcba817ff01b4
https://doi.org/10.1016/j.tiv.2012.05.006

Phosphorylation of a Conserved Serine in the Deoxyribonucleic Acid Binding Domain of Nuclear Receptors Alters Intracellular Localization

Autor: Frances M. Sladek, Vladimir Parpura, Yann Brelivet, Vedrana Montana, Bryce M. Paschal, Kai Sun, Karthikeyani Chellappa, Yutaka Maeda, Dino Moras

Publikováno v: Molecular Endocrinology-Baltimore
Molecular Endocrinology-Baltimore-, Endocrine Society, 2007, 21 (6), pp.1297-311. ⟨10.1210/me.2006-0300⟩
Molecular Endocrinology-Baltimore-, 2007, 21 (6), pp.1297-311. ⟨10.1210/me.2006-0300⟩

Nuclear receptors (NRs) are a superfamily of transcription factors whose genomic functions are known to be activated by lipophilic ligands, but little is known about how to deactivate them or how to turn on their nongenomic functions. One obvious mec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8993b449b1987b40caae7e6ff332c39e
https://doi.org/10.1210/me.2006-0300

The neuroendocrine protein VGF is sorted into dense-core granules and is secreted apically by polarized rat thyroid epithelial cells

Autor: Roberta Possenti, Claudia Puri, Patrizia Rosa, Carlo Tacchetti, Andrea Levi, Lucio Nitsch, Flaviana Gentile, Annunziata Corteggio, Gaetano Calì, Chiara Zurzolo, Federico Calegari

Publikováno v: Experimental cell research (2004).
info:cnr-pdr/source/autori:Gentile, F; Cali, G; Zurzolo, C; Corteggio, A; Rosa, P; Calegari, F; Levi, A; Possenti, R; Puri, C; Tacchetti, C; Nitsch, L/titolo:The neuroendocrine protein VGF is sorted into dense-core granules and is secreted apically by polarized rat thyroid epithelial cells/doi:/rivista:Experimental cell research/anno:2004/pagina_da:/pagina_a:/intervallo_pagine:/volume
Experimental Cell Research
Experimental Cell Research, Elsevier, 2004, 295 (1), pp.269-80. ⟨10.1016/j.yexcr.2004.01.010⟩
Experimental Cell Research, 2004, 295 (1), pp.269-80. ⟨10.1016/j.yexcr.2004.01.010⟩
Experimental cell research 295 (2004): 269–280. doi:10.1016/j.yexcr.2004.01.010
info:cnr-pdr/source/autori:Gentile F, Calì G, Zurzolo C, Corteggio A, Rosa P, Calegari F, Levi A, Possenti R, Puri C, Tacchetti C, Nitsch L./titolo:The neuroendocrine protein VGF is sorted into dense-core granules and is secreted apically by polarized rat thyroid epithelial cells./doi:10.1016%2Fj.yexcr.2004.01.010/rivista:Experimental cell research/anno:2004/pagina_da:269/pagina_a:280/intervallo_pagine:269–280/volume:295

We have expressed the neuroendocrine VGF protein in FRT rat thyroid cells to study the molecular mechanisms of its sorting to the regulated and polarized pathways of secretion. By immunoelectron microscopy, we have demonstrated that VGF localizes in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b85bb694785e2d24a12c6a3aa9ae59e
https://doi.org/10.1016/j.yexcr.2004.01.010

Protectin DX, a double lipoxygenase product of DHA, inhibits both ROS production in human neutrophils and cyclooxygenase activities

Autor: Tarek Boussetta, Michel Guichardant, Michèle Fay, Fathi Driss, Jamel El-Benna, Michel Lagarde, Karama Makni-Maalej, Miao Liu

Publikováno v: Lipids
Lipids, Springer Verlag, 2014, 49 (1), pp.49-57. ⟨10.1007/s11745-013-3863-6⟩

International audience; Neutrophils play a major role in inflammation by releasing large amounts of reactive oxygen species (ROS) produced by NADPH oxidase (NOX) and myeloperoxidase (MPO). This ROS overproduction is mediated by phosphorylation of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b84d9032d6fe953b310bba129650b6d
https://pubmed.ncbi.nlm.nih.gov/24254970