Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia

Autor: Mirjam Lutz, Ekaterina Friebel, Roland S. Liblau, Antoine Roquilly, Guillaume Martin-Blondel, Manfred Claassen, Benjamin Gaborit, Manuel Kauffmann, Sepideh Babaei, Donatella De Feo, Nicolás Gonzalo Núñez, Nisar P. Malek, Chiara Alberti, Sally Al-Hajj, Susanne Unger, Siri Goepel, Ikram Ayoub, Helene A. Häberle, Jakob Nilsson, Nicole Puertas Jurado, Peter Rosenberger, Stefanie Kreutmair, Sinduya Krishnarajah, Burkhard Becher, Michael Bitzer, Florian Ingelfinger

Publikováno v: Immunity
Immunity, 2021, 54 (7), pp.1578-1593.e5. ⟨10.1016/j.immuni.2021.05.002⟩

Immune profiling of COVID-19 patients has identified numerous alterations in both innate and adaptive immunity. However, whether those changes are specific to SARS-CoV-2 or driven by a general inflammatory response shared across severely ill pneumoni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a70271704dd1c2b9bc69005e3664513
https://doi.org/10.1016/j.immuni.2021.05.002

Les rétrovirus endogènes : un rôle clé dans la programmation des lymphocytes T CD4

Autor: Véronique Adoue, Olivier Joffre

Publikováno v: médecine/sciences
médecine/sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩
médecine/sciences, EDP Sciences, 2020, 36 (3), pp.253-260. ⟨10.1051/medsci/2020022⟩

Upon priming by dendritic cells, naïve CD4 T lymphocytes are exposed to distinct molecular environments depending on the nature of the pathological stimulus. In response, they mobilize different gene networks that establish lineage-specific developm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d8bbf56b7f22d0ec282cc76e4db22f
https://doi.org/10.1051/medsci/2020022

In Untreated HIV-1–Infected Children, PBMC-Associated HIV DNA Levels and Cell-Free HIV RNA Levels Are Correlated to Distinct T-lymphocyte Populations

Autor: Céline Didier, Christine Rouzioux, Stéphane Blanche, Marianne Burgard, Daniel Scott-Algara, Yves Rivière, Florence Buseyne

Publikováno v: Journal of Acquired Immune Deficiency Syndromes
Journal of Acquired Immune Deficiency Syndromes, Lippincott, Williams & Wilkins, 2010, 53 (5), pp.553-563. ⟨10.1097/QAI.0b013e3181cf060f⟩
Journal of Acquired Immune Deficiency Syndromes, 2010, 53 (5), pp.553-63. <10.1097/QAI.0b013e3181cf060f>
Journal of Acquired Immune Deficiency Syndromes, Lippincott, Williams & Wilkins, 2010, 53 (5), pp.553-563. 〈10.1097/QAI.0b013e3181cf060f〉
Journal of Acquired Immune Deficiency Syndromes-JAIDS
Journal of Acquired Immune Deficiency Syndromes-JAIDS, 2010, 53 (5), pp.553-563. ⟨10.1097/QAI.0b013e3181cf060f⟩

International audience; Background: Clinical studies support biologically independent roles of cell-free HIV particles and HIV-infected cells in disease progression. The associations between the level of infected cells and immune markers have been po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac44837a51de96786cecad033b47989
https://doi.org/10.1097/qai.0b013e3181cf060f

Low DPP4 expression and activity in multiple sclerosis

Autor: Rocío Ramos-Medina, Bárbara Alonso, Armanda Casrouge, Janet Vega, Matthew L. Albert, Marta Tejera-Alhambra, Silvia Sánchez-Ramón, Clara de Andrés

Publikováno v: Clinical Immunology
Clinical Immunology, Elsevier, 2014, 150 (2), pp.170-183. ⟨10.1016/j.clim.2013.11.011⟩
Clinical Immunology, 2014, 150 (2), pp.170-183. ⟨10.1016/j.clim.2013.11.011⟩

International audience; Multiple sclerosis (MS) is a prototypic Th1/Th17 chronic autoimmune disease of the central nervous system. Dipeptidyl peptidase 4 (DPP4 or CD26) is a multifunctional molecule involved in autoimmune diseases' pathophysiology. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073eb035795c59681898d72ef93eb841

IL-23/IL-17A Axis Correlates with the Nitric Oxide Pathway in Inflammatory Bowel Disease: Immunomodulatory Effect of Retinoic Acid

Autor: Imene Soufli, Chafia Touil-Boukoffa, Hayet Rafa, Nadira Delhem, Ryma Toumi, Houria Saoula, Yvan de Launoit, M’hamed Nakmouche, Olivier Moralès, Oussama Medjeber, Mourad Belkhelfa

Publikováno v: Journal of Interferon and Cytokine Research
Journal of Interferon and Cytokine Research, Mary Ann Liebert, 2013, 33 (7), pp.355-368. ⟨10.1089/jir.2012.0063⟩

International audience; Inflammatory bowel diseases (IBDs) are chronic inflammatory diseases of the gastrointestinal tract, which are clinically present as 1 of the 2 disorders, Crohn's disease (CD) or ulcerative colitis (UC) (Rogler 2004). The immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a681e8219310a30fbf46f18c46e3e251
https://hal.archives-ouvertes.fr/hal-02395835