Adaptive landscape flattening in amino acid sequence space for the computational design of protein:peptide binding

Autor: Thomas Simonson, Francesco Villa, Nicolas Panel, Xingyu Chen

Publikováno v: Journal of Chemical Physics
Journal of Chemical Physics, American Institute of Physics, 2018, 149 (7), pp.072302. ⟨10.1063/1.5022249⟩

International audience; For the high throughput design of protein:peptide binding, one must explore a vast space of amino acid sequences in search of low binding free energies. This complex problem is usually addressed with either simple heuristic sc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bacfcd013a2ab009841d86812aef832
https://pubmed.ncbi.nlm.nih.gov/30134674